Actively separated microneedle patch for sustained-release of growth hormone to treat growth hormone deficiency

Actively separated microneedle patch for sustained-release of growth hormone to treat growth hormone deficiency

Growth hormone deficiency (GHD) has become a serious healthcare burden, and presents a huge impact on the physical and mental health of patients. Here, we developed an actively separated microneedle patch (PAA/NaHCO3-Silk MN) based on silk protein for sustained release of recombinant human growth ho...

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Bibliographic Details
Main Authors: Li Yang, Qingyun Liu, Xinhui Wang, Nansha Gao, Xiuzhen Li, Hongzhong Chen, Lin Mei, Xiaowei Zeng
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Microneedle
Silk protein
Self-administration
Sustained-release
Actively separated
Growth hormone deficiency
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383522002039

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