Effects of Positive End-Expiratory Pressure on Intraocular Pressure during One-Lung Ventilation in the Lateral Decubitus Position—A Prospective Randomized Trial
<i>Background and Objectives</i>: The effect of positive end-expiratory pressure (PEEP) on intraocular pressure (IOP) is debatable. There have been no studies investigating the effects of PEEP on IOP during one-lung ventilation (OLV). We aimed to investigate the effects of PEEP on IOP in...
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| Format: | Article |
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MDPI AG
2022-07-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/58/7/940 |
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| author | Yong Shin Kim Kwon Hui Seo Yeon Soo Jeon Jang Hyeok In Hong Soo Jung Yoo Jung Park Eun Hwa Jun Eunju Yu |
| author_facet | Yong Shin Kim Kwon Hui Seo Yeon Soo Jeon Jang Hyeok In Hong Soo Jung Yoo Jung Park Eun Hwa Jun Eunju Yu |
| author_sort | Yong Shin Kim |
| collection | DOAJ |
| description | <i>Background and Objectives</i>: The effect of positive end-expiratory pressure (PEEP) on intraocular pressure (IOP) is debatable. There have been no studies investigating the effects of PEEP on IOP during one-lung ventilation (OLV). We aimed to investigate the effects of PEEP on IOP in patients undergoing OLV for video-assisted thoracoscopic surgery (VATs). <i>Materials and Methods</i>: Fifty-two patients undergoing VATs were divided into a zero-PEEP (ZEEP) and a 6 cmH<sub>2</sub>O of PEEP (PEEP) groups. IOP, ocular perfusion pressure (OPP), and respiratory and hemodynamic parameters were measured before induction (T1), immediately following endotracheal intubation (T2), 30 min (T3) and 60 min (T4) after a position change to the lateral decubitus position (LDP) and OLV, and 10 min following two-lung ventilation near the end of the surgery (T5). <i>Results</i>: There was no significant difference in IOP and OPP between the two groups. The IOP of the dependent eye was significantly higher than that of the non-dependent eye during LDP in both groups. Peak inspiratory pressure was significantly higher in the PEEP group than in the ZEEP group at T3–T5. Dynamic compliance was significantly higher in the PEEP group than in the ZEEP group at T2–T5. The ratio of arterial oxygen partial pressure to fractional inspired oxygen was significantly higher in the PEEP group than in the ZEEP group at T4. <i>Conclusions</i>: Applying 6 cmH<sub>2</sub>O of PEEP did not increase IOP but enhanced dynamic compliance and oxygenation during OLV. These results suggest that 6 cmH<sub>2</sub>O of PEEP can be safely applied during OLV in LDP. |
| first_indexed | 2024-03-09T06:14:34Z |
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| id | doaj.art-49b8073b1b144baf8b3dab7bfe896942 |
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| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-09T06:14:34Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-49b8073b1b144baf8b3dab7bfe8969422023-12-03T11:54:55ZengMDPI AGMedicina1010-660X1648-91442022-07-0158794010.3390/medicina58070940Effects of Positive End-Expiratory Pressure on Intraocular Pressure during One-Lung Ventilation in the Lateral Decubitus Position—A Prospective Randomized TrialYong Shin Kim0Kwon Hui Seo1Yeon Soo Jeon2Jang Hyeok In3Hong Soo Jung4Yoo Jung Park5Eun Hwa Jun6Eunju Yu7Department of Anesthesiology and Pain Medicine, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Suwon 16247, KoreaDepartment of Anesthesiology and Pain Medicine, Hallym University Sacred Heart Hospital, Hallym University School of Medicine, Anyang 14068, KoreaDepartment of Anesthesiology and Pain Medicine, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Suwon 16247, KoreaDepartment of Anesthesiology and Pain Medicine, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Suwon 16247, KoreaDepartment of Anesthesiology and Pain Medicine, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Suwon 16247, KoreaDepartment of Anesthesiology and Pain Medicine, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Suwon 16247, KoreaDepartment of Anesthesiology and Pain Medicine, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Suwon 16247, KoreaDepartment of Anesthesiology and Pain Medicine, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Suwon 16247, Korea<i>Background and Objectives</i>: The effect of positive end-expiratory pressure (PEEP) on intraocular pressure (IOP) is debatable. There have been no studies investigating the effects of PEEP on IOP during one-lung ventilation (OLV). We aimed to investigate the effects of PEEP on IOP in patients undergoing OLV for video-assisted thoracoscopic surgery (VATs). <i>Materials and Methods</i>: Fifty-two patients undergoing VATs were divided into a zero-PEEP (ZEEP) and a 6 cmH<sub>2</sub>O of PEEP (PEEP) groups. IOP, ocular perfusion pressure (OPP), and respiratory and hemodynamic parameters were measured before induction (T1), immediately following endotracheal intubation (T2), 30 min (T3) and 60 min (T4) after a position change to the lateral decubitus position (LDP) and OLV, and 10 min following two-lung ventilation near the end of the surgery (T5). <i>Results</i>: There was no significant difference in IOP and OPP between the two groups. The IOP of the dependent eye was significantly higher than that of the non-dependent eye during LDP in both groups. Peak inspiratory pressure was significantly higher in the PEEP group than in the ZEEP group at T3–T5. Dynamic compliance was significantly higher in the PEEP group than in the ZEEP group at T2–T5. The ratio of arterial oxygen partial pressure to fractional inspired oxygen was significantly higher in the PEEP group than in the ZEEP group at T4. <i>Conclusions</i>: Applying 6 cmH<sub>2</sub>O of PEEP did not increase IOP but enhanced dynamic compliance and oxygenation during OLV. These results suggest that 6 cmH<sub>2</sub>O of PEEP can be safely applied during OLV in LDP.https://www.mdpi.com/1648-9144/58/7/940intraocular pressurelateral decubitus positionocular perfusion pressureone-lung ventilationpositive end expiratory pressurethoracoscopy |
| spellingShingle | Yong Shin Kim Kwon Hui Seo Yeon Soo Jeon Jang Hyeok In Hong Soo Jung Yoo Jung Park Eun Hwa Jun Eunju Yu Effects of Positive End-Expiratory Pressure on Intraocular Pressure during One-Lung Ventilation in the Lateral Decubitus Position—A Prospective Randomized Trial Medicina intraocular pressure lateral decubitus position ocular perfusion pressure one-lung ventilation positive end expiratory pressure thoracoscopy |
| title | Effects of Positive End-Expiratory Pressure on Intraocular Pressure during One-Lung Ventilation in the Lateral Decubitus Position—A Prospective Randomized Trial |
| title_full | Effects of Positive End-Expiratory Pressure on Intraocular Pressure during One-Lung Ventilation in the Lateral Decubitus Position—A Prospective Randomized Trial |
| title_fullStr | Effects of Positive End-Expiratory Pressure on Intraocular Pressure during One-Lung Ventilation in the Lateral Decubitus Position—A Prospective Randomized Trial |
| title_full_unstemmed | Effects of Positive End-Expiratory Pressure on Intraocular Pressure during One-Lung Ventilation in the Lateral Decubitus Position—A Prospective Randomized Trial |
| title_short | Effects of Positive End-Expiratory Pressure on Intraocular Pressure during One-Lung Ventilation in the Lateral Decubitus Position—A Prospective Randomized Trial |
| title_sort | effects of positive end expiratory pressure on intraocular pressure during one lung ventilation in the lateral decubitus position a prospective randomized trial |
| topic | intraocular pressure lateral decubitus position ocular perfusion pressure one-lung ventilation positive end expiratory pressure thoracoscopy |
| url | https://www.mdpi.com/1648-9144/58/7/940 |
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