Genetic control of lithium sensitivity and regulation of inositol biosynthetic genes.

Lithium (Li(+)) is a common treatment for bipolar mood disorder, a major psychiatric illness with a lifetime prevalence of more than 1%. Risk of bipolar disorder is heavily influenced by genetic predisposition, but is a complex genetic trait and, to date, genetic studies have provided little insight...

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Bibliographic Details
Main Authors: Jason King, Melanie Keim, Regina Teo, Karin E Weening, Mridu Kapur, Karina McQuillan, Jonathan Ryves, Ben Rogers, Emma Dalton, Robin S B Williams, Adrian J Harwood
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2887444?pdf=render