Cingulate cortex morphology impacts on neurofunctional activity and behavioral performance in interference tasks
Abstract Inhibitory control is the capacity to withhold or suppress a thought or action intentionally. The anterior Midcingulate Cortex (aMCC) participates in response inhibition, a proxy measure of inhibitory control. Recent research suggests that response inhibition is modulated by individual vari...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-08-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-17557-6 |
| _version_ | 1798042517245001728 |
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| author | Davide Fedeli Nicola Del Maschio Gianpaolo Del Mauro Federica Defendenti Simone Sulpizio Jubin Abutalebi |
| author_facet | Davide Fedeli Nicola Del Maschio Gianpaolo Del Mauro Federica Defendenti Simone Sulpizio Jubin Abutalebi |
| author_sort | Davide Fedeli |
| collection | DOAJ |
| description | Abstract Inhibitory control is the capacity to withhold or suppress a thought or action intentionally. The anterior Midcingulate Cortex (aMCC) participates in response inhibition, a proxy measure of inhibitory control. Recent research suggests that response inhibition is modulated by individual variability in the aMCC sulcal morphology. However, no study has investigated if this phenomenon is associated with neurofunctional differences during a task. In this study, 42 participants performed an Attention Network Task and a Numerical Stroop task in an MRI scanner. We investigated differences in brain activity and response inhibition efficiency between individuals with symmetric and asymmetric aMCC sulcal patterns. The results showed that aMCC morphological variability is partly associated with inhibitory control, and revealed greater activation in individuals with symmetric patterns during the Stroop task. Our findings provide novel insights into the functional correlates of the relationship between aMCC morphology and executive abilities. |
| first_indexed | 2024-04-11T22:36:34Z |
| format | Article |
| id | doaj.art-49bd3975eaa14dc0997449edb6f45ad4 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-11T22:36:34Z |
| publishDate | 2022-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-49bd3975eaa14dc0997449edb6f45ad42022-12-22T03:59:11ZengNature PortfolioScientific Reports2045-23222022-08-0112111410.1038/s41598-022-17557-6Cingulate cortex morphology impacts on neurofunctional activity and behavioral performance in interference tasksDavide Fedeli0Nicola Del Maschio1Gianpaolo Del Mauro2Federica Defendenti3Simone Sulpizio4Jubin Abutalebi5Neuroradiology Department, Fondazione IRCCS Istituto Neurologico Carlo BestaCentre for Neurolinguistics and Psycholinguistics (CNPL), Università Vita-Salute San RaffaeleCentre for Neurolinguistics and Psycholinguistics (CNPL), Università Vita-Salute San RaffaeleCentre for Neurolinguistics and Psycholinguistics (CNPL), Università Vita-Salute San RaffaeleDepartment of Psychology, University of Milano-BicoccaThe Arctic University of NorwayAbstract Inhibitory control is the capacity to withhold or suppress a thought or action intentionally. The anterior Midcingulate Cortex (aMCC) participates in response inhibition, a proxy measure of inhibitory control. Recent research suggests that response inhibition is modulated by individual variability in the aMCC sulcal morphology. However, no study has investigated if this phenomenon is associated with neurofunctional differences during a task. In this study, 42 participants performed an Attention Network Task and a Numerical Stroop task in an MRI scanner. We investigated differences in brain activity and response inhibition efficiency between individuals with symmetric and asymmetric aMCC sulcal patterns. The results showed that aMCC morphological variability is partly associated with inhibitory control, and revealed greater activation in individuals with symmetric patterns during the Stroop task. Our findings provide novel insights into the functional correlates of the relationship between aMCC morphology and executive abilities.https://doi.org/10.1038/s41598-022-17557-6 |
| spellingShingle | Davide Fedeli Nicola Del Maschio Gianpaolo Del Mauro Federica Defendenti Simone Sulpizio Jubin Abutalebi Cingulate cortex morphology impacts on neurofunctional activity and behavioral performance in interference tasks Scientific Reports |
| title | Cingulate cortex morphology impacts on neurofunctional activity and behavioral performance in interference tasks |
| title_full | Cingulate cortex morphology impacts on neurofunctional activity and behavioral performance in interference tasks |
| title_fullStr | Cingulate cortex morphology impacts on neurofunctional activity and behavioral performance in interference tasks |
| title_full_unstemmed | Cingulate cortex morphology impacts on neurofunctional activity and behavioral performance in interference tasks |
| title_short | Cingulate cortex morphology impacts on neurofunctional activity and behavioral performance in interference tasks |
| title_sort | cingulate cortex morphology impacts on neurofunctional activity and behavioral performance in interference tasks |
| url | https://doi.org/10.1038/s41598-022-17557-6 |
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