Hypericin Inhibit Alpha-Coronavirus Replication by Targeting 3CL Protease

Hypericin Inhibit Alpha-Coronavirus Replication by Targeting 3CL Protease

The porcine epidemic diarrhea virus (PEDV) is an <i>Alphacoronavirus</i> (α-CoV) that causes high mortality in infected piglets, resulting in serious economic losses in the farming industry. Hypericin is a dianthrone compound that has been shown as an antiviral activity on several viruse...

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Bibliographic Details
Main Authors: Yue Zhang, Huijie Chen, Mengmeng Zou, Rick Oerlemans, Changhao Shao, Yudong Ren, Ruili Zhang, Xiaodan Huang, Guangxing Li, Yingying Cong
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Viruses
Subjects:
α-CoV
PEDV
hypericin
3CL protease
TGEV
Online Access:https://www.mdpi.com/1999-4915/13/9/1825

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