Modulation of the Lipid Profile of Reconstructed Skin Substitutes after Essential Fatty Acid Supplementation Affects Testosterone Permeability

Modulation of the Lipid Profile of Reconstructed Skin Substitutes after Essential Fatty Acid Supplementation Affects Testosterone Permeability

Skin models with efficient skin barrier function are required for percutaneous absorption studies. The contribution of media supplementation with n-3 and n-6 polyunsaturated fatty acids (PUFAs) to the development of the skin barrier function of in vitro skin models remains incompletely understood. T...

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Bibliographic Details
Main Authors: Mélissa Simard, Pierre Julien, Julie Fradette, Roxane Pouliot
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cells
Subjects:
skin substitutes
skin barrier function
polyunsaturated fatty acids
tissue engineering
lipidomics
Online Access:https://www.mdpi.com/2073-4409/8/10/1142

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