Rhupus Syndrome: An Overlap with Renal Complications

Rhupus syndrome is a rare condition of overlap of Rheumatoid Arthritis (RA) and Systemic Lupus Erythematosus (SLE) presenting with erosive polyarthritis and symptoms of SLE. It occasionally has renal involvement as its complication makes the diagnosis more difficult. Here the authors present a case...

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Main Authors: Priyabhasini Chinmoyee Roy, Subal Kumar Pradhan
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2020-02-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/13480/42826_CE[Ra1]_F(SL)_PF1(AG_KM)_PFA(KM)_PB(AG_KM)_PN(SL).pdf
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author Priyabhasini Chinmoyee Roy
Subal Kumar Pradhan
author_facet Priyabhasini Chinmoyee Roy
Subal Kumar Pradhan
author_sort Priyabhasini Chinmoyee Roy
collection DOAJ
description Rhupus syndrome is a rare condition of overlap of Rheumatoid Arthritis (RA) and Systemic Lupus Erythematosus (SLE) presenting with erosive polyarthritis and symptoms of SLE. It occasionally has renal involvement as its complication makes the diagnosis more difficult. Here the authors present a case of a 13-year-old female with severe arthritis, which gradually progressed into lupus nephritis with the presence of specific autoantibodies confirming the diagnosis of Rhupus. The child was managed with disease modifying anti-rheumatic drug (hydroxychloroquine), immunosuppressants (mycophenolate mofetil), steroid (prednisolone) and calcium channel blocker (amlodipine). Accurate diagnosis is the key for early detection since Rhupus is a very rare disorder with very limited reported cases.
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spelling doaj.art-49c00a8132264578b2e4d6e9661a5b532022-12-22T01:31:26ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2020-02-01142SD01SD0210.7860/JCDR/2020/42826.13480Rhupus Syndrome: An Overlap with Renal ComplicationsPriyabhasini Chinmoyee Roy0Subal Kumar Pradhan1Senior Resident, Department of Paediatrics Nephrology, SVP Post Graduate Institute of Paediatrics and SCB Medical College, Cuttack, Odisha, India.Paediatric Nephrologist, Associate Professor, Department of Paediatrics Nephrology, SVP Post Graduate Institute of Paediatrics and SCB Medical College, Cuttack, Odisha, India.Rhupus syndrome is a rare condition of overlap of Rheumatoid Arthritis (RA) and Systemic Lupus Erythematosus (SLE) presenting with erosive polyarthritis and symptoms of SLE. It occasionally has renal involvement as its complication makes the diagnosis more difficult. Here the authors present a case of a 13-year-old female with severe arthritis, which gradually progressed into lupus nephritis with the presence of specific autoantibodies confirming the diagnosis of Rhupus. The child was managed with disease modifying anti-rheumatic drug (hydroxychloroquine), immunosuppressants (mycophenolate mofetil), steroid (prednisolone) and calcium channel blocker (amlodipine). Accurate diagnosis is the key for early detection since Rhupus is a very rare disorder with very limited reported cases.https://jcdr.net/articles/PDF/13480/42826_CE[Ra1]_F(SL)_PF1(AG_KM)_PFA(KM)_PB(AG_KM)_PN(SL).pdfdiagnosisrheumatoid arthritissystemic lupus erythematosus
spellingShingle Priyabhasini Chinmoyee Roy
Subal Kumar Pradhan
Rhupus Syndrome: An Overlap with Renal Complications
Journal of Clinical and Diagnostic Research
diagnosis
rheumatoid arthritis
systemic lupus erythematosus
title Rhupus Syndrome: An Overlap with Renal Complications
title_full Rhupus Syndrome: An Overlap with Renal Complications
title_fullStr Rhupus Syndrome: An Overlap with Renal Complications
title_full_unstemmed Rhupus Syndrome: An Overlap with Renal Complications
title_short Rhupus Syndrome: An Overlap with Renal Complications
title_sort rhupus syndrome an overlap with renal complications
topic diagnosis
rheumatoid arthritis
systemic lupus erythematosus
url https://jcdr.net/articles/PDF/13480/42826_CE[Ra1]_F(SL)_PF1(AG_KM)_PFA(KM)_PB(AG_KM)_PN(SL).pdf
work_keys_str_mv AT priyabhasinichinmoyeeroy rhupussyndromeanoverlapwithrenalcomplications
AT subalkumarpradhan rhupussyndromeanoverlapwithrenalcomplications