Risk factors for the first episode of peritonitis in Southern Chinese continuous ambulatory peritoneal dialysis patients.
The first episode of peritonitis affects survival of the peritoneal membrane as a medium for dialysis as well as survival of patients. The aim of this study is to investigate risk factors associated with the first episode of peritonitis in Southern Chinese continuous ambulatory peritoneal dialysis (...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4164648?pdf=render |
| _version_ | 1818318772109312000 |
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| author | Xiaoguang Fan Rong Huang Juan Wang Hongjian Ye Qunying Guo Chunyan Yi Jianxiong Lin Qian Zhou Fengmin Shao Xueqing Yu Xiao Yang |
| author_facet | Xiaoguang Fan Rong Huang Juan Wang Hongjian Ye Qunying Guo Chunyan Yi Jianxiong Lin Qian Zhou Fengmin Shao Xueqing Yu Xiao Yang |
| author_sort | Xiaoguang Fan |
| collection | DOAJ |
| description | The first episode of peritonitis affects survival of the peritoneal membrane as a medium for dialysis as well as survival of patients. The aim of this study is to investigate risk factors associated with the first episode of peritonitis in Southern Chinese continuous ambulatory peritoneal dialysis (CAPD) patients.This is a single-center, retrospective, cohort study. All incident CAPD patients from 1 January 2006 to 31 December 2010 were recruited, and followed up until their first episode of peritonitis or 31 December, 2012. Baseline demographic, socioeconomic, clinical and laboratory data were collected. Cox proportional model was used to determine the factors associated with the first episode of peritonitis.In a cumulative 30756.5 patient-months follow-up (the median vintage 26.1 months) of 1117 CAPD patients, 309(27.7%) patients presented the first episodes of peritonitis. The cumulative peritonitis-free survival was 86.2%, 78.1%, 71.4% and 57.8% at 1, 2, 3 and 5 year, respectively. The multivariate analysis showed that factors associated with risk for the first episode of peritonitis were elderly patients (>65 years) [hazard ratio (HR) = 1.427, 95% confidence interval (CI) = 1.051 to 1.938, P = 0.023], male(HR = 1.315, 95% CI = 1.028 to 1.684, P = 0.030), lower education level (HR = 1.446, 95% CI: 1.127 to 1.855, P = 0.004) and albumin <38g/L (HR = 1.425, 95% CI: 1.112 to 1.825, P = 0.005).Older age, male, lower educational level and hypoalbuminemia at the commencement of PD were the risk factors associated with the first episode of peritonitis in Southern Chinese CAPD patients. |
| first_indexed | 2024-12-13T09:58:31Z |
| format | Article |
| id | doaj.art-49c10a9d857d416e9db1ab4be6cd6e22 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-13T09:58:31Z |
| publishDate | 2014-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-49c10a9d857d416e9db1ab4be6cd6e222022-12-21T23:51:43ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0199e10748510.1371/journal.pone.0107485Risk factors for the first episode of peritonitis in Southern Chinese continuous ambulatory peritoneal dialysis patients.Xiaoguang FanRong HuangJuan WangHongjian YeQunying GuoChunyan YiJianxiong LinQian ZhouFengmin ShaoXueqing YuXiao YangThe first episode of peritonitis affects survival of the peritoneal membrane as a medium for dialysis as well as survival of patients. The aim of this study is to investigate risk factors associated with the first episode of peritonitis in Southern Chinese continuous ambulatory peritoneal dialysis (CAPD) patients.This is a single-center, retrospective, cohort study. All incident CAPD patients from 1 January 2006 to 31 December 2010 were recruited, and followed up until their first episode of peritonitis or 31 December, 2012. Baseline demographic, socioeconomic, clinical and laboratory data were collected. Cox proportional model was used to determine the factors associated with the first episode of peritonitis.In a cumulative 30756.5 patient-months follow-up (the median vintage 26.1 months) of 1117 CAPD patients, 309(27.7%) patients presented the first episodes of peritonitis. The cumulative peritonitis-free survival was 86.2%, 78.1%, 71.4% and 57.8% at 1, 2, 3 and 5 year, respectively. The multivariate analysis showed that factors associated with risk for the first episode of peritonitis were elderly patients (>65 years) [hazard ratio (HR) = 1.427, 95% confidence interval (CI) = 1.051 to 1.938, P = 0.023], male(HR = 1.315, 95% CI = 1.028 to 1.684, P = 0.030), lower education level (HR = 1.446, 95% CI: 1.127 to 1.855, P = 0.004) and albumin <38g/L (HR = 1.425, 95% CI: 1.112 to 1.825, P = 0.005).Older age, male, lower educational level and hypoalbuminemia at the commencement of PD were the risk factors associated with the first episode of peritonitis in Southern Chinese CAPD patients.http://europepmc.org/articles/PMC4164648?pdf=render |
| spellingShingle | Xiaoguang Fan Rong Huang Juan Wang Hongjian Ye Qunying Guo Chunyan Yi Jianxiong Lin Qian Zhou Fengmin Shao Xueqing Yu Xiao Yang Risk factors for the first episode of peritonitis in Southern Chinese continuous ambulatory peritoneal dialysis patients. PLoS ONE |
| title | Risk factors for the first episode of peritonitis in Southern Chinese continuous ambulatory peritoneal dialysis patients. |
| title_full | Risk factors for the first episode of peritonitis in Southern Chinese continuous ambulatory peritoneal dialysis patients. |
| title_fullStr | Risk factors for the first episode of peritonitis in Southern Chinese continuous ambulatory peritoneal dialysis patients. |
| title_full_unstemmed | Risk factors for the first episode of peritonitis in Southern Chinese continuous ambulatory peritoneal dialysis patients. |
| title_short | Risk factors for the first episode of peritonitis in Southern Chinese continuous ambulatory peritoneal dialysis patients. |
| title_sort | risk factors for the first episode of peritonitis in southern chinese continuous ambulatory peritoneal dialysis patients |
| url | http://europepmc.org/articles/PMC4164648?pdf=render |
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