Effect of electron beam irradiation sterilization on the Tibetan medicine Bawei Chenxiang powder

To evaluate the sterilization effect of electron beam irradiation on Tibetan medicine Bawei Chenxiang powder and the influence on the active ingredients, medicine samples were irradiated with electron beam at doses of 0 kGy, 5 kGy, 7 kGy, 10 kGy, and 60Co γ at 7 kGy. The microbial and active substan...

Full description

Bibliographic Details
Main Authors: DE Jizhuoga, WANG Wei, DE Jicuomu, TIAN Lei, LAN Liqiong, CHEN Hao, SUN Qun, GAO Peng
Format: Article
Language:zho
Published: Science Press 2022-10-01
Series:Fushe yanjiu yu fushe gongyi xuebao
Subjects:
Online Access:http://www.fs.sinap.ac.cn/thesisDetails#10.11889/j.1000-3436.2022-0030&lang=zh
_version_ 1811170328571805696
author DE Jizhuoga
WANG Wei
DE Jicuomu
TIAN Lei
LAN Liqiong
CHEN Hao
SUN Qun
GAO Peng
author_facet DE Jizhuoga
WANG Wei
DE Jicuomu
TIAN Lei
LAN Liqiong
CHEN Hao
SUN Qun
GAO Peng
author_sort DE Jizhuoga
collection DOAJ
description To evaluate the sterilization effect of electron beam irradiation on Tibetan medicine Bawei Chenxiang powder and the influence on the active ingredients, medicine samples were irradiated with electron beam at doses of 0 kGy, 5 kGy, 7 kGy, 10 kGy, and 60Co γ at 7 kGy. The microbial and active substance costunolide levels were measured within 7 d after irradiation and after accelerated storage at 49 ℃ for 3 months, respectively. The results showed that electron beam and 60Co γ irradiation significantly reduced the total number of microorganisms in Bawei Chenxiang powder. Irradiation by electron beams at 5 kGy and 10 kGy reduced the total number of microorganisms in Bawei Chenxiang powder to the maximum requirement suggested by the Chinese Pharmacopoeia without significantly decreasing the amount of active ingredient. In conclusion, electron beam irradiation can effectively improve the microbial index of Bawei Chenxing powder, and 5 kGy is the optimal processing dose for this purpose.
first_indexed 2024-04-10T16:55:09Z
format Article
id doaj.art-49c1b3cede564cb089721807ead036cc
institution Directory Open Access Journal
issn 1000-3436
language zho
last_indexed 2024-04-10T16:55:09Z
publishDate 2022-10-01
publisher Science Press
record_format Article
series Fushe yanjiu yu fushe gongyi xuebao
spelling doaj.art-49c1b3cede564cb089721807ead036cc2023-02-07T07:41:58ZzhoScience PressFushe yanjiu yu fushe gongyi xuebao1000-34362022-10-01405637010.11889/j.1000-3436.2022-00301000-3436(2022)05-0063-08Effect of electron beam irradiation sterilization on the Tibetan medicine Bawei Chenxiang powderDE Jizhuoga0WANG Wei1DE Jicuomu2TIAN Lei3LAN Liqiong4CHEN Hao5SUN Qun6GAO Peng7Tibet Institute for Food and Drug Control, Lhasa 850000, ChinaTibet Institute for Food and Drug Control, Lhasa 850000, ChinaTibet Institute for Food and Drug Control, Lhasa 850000, ChinaSichuan University, Chengdu 610000, ChinaSichuan University, Chengdu 610000, ChinaSichuan Institute of Atomic Energy, Chengdu 610101, ChinaSichuan University, Chengdu 610000, ChinaSichuan Institute of Atomic Energy, Chengdu 610101, ChinaTo evaluate the sterilization effect of electron beam irradiation on Tibetan medicine Bawei Chenxiang powder and the influence on the active ingredients, medicine samples were irradiated with electron beam at doses of 0 kGy, 5 kGy, 7 kGy, 10 kGy, and 60Co γ at 7 kGy. The microbial and active substance costunolide levels were measured within 7 d after irradiation and after accelerated storage at 49 ℃ for 3 months, respectively. The results showed that electron beam and 60Co γ irradiation significantly reduced the total number of microorganisms in Bawei Chenxiang powder. Irradiation by electron beams at 5 kGy and 10 kGy reduced the total number of microorganisms in Bawei Chenxiang powder to the maximum requirement suggested by the Chinese Pharmacopoeia without significantly decreasing the amount of active ingredient. In conclusion, electron beam irradiation can effectively improve the microbial index of Bawei Chenxing powder, and 5 kGy is the optimal processing dose for this purpose.http://www.fs.sinap.ac.cn/thesisDetails#10.11889/j.1000-3436.2022-0030&lang=zhelectron beamirradiation sterilizationbawei chenxiang powdertotal number of microorganismsactive ingredients
spellingShingle DE Jizhuoga
WANG Wei
DE Jicuomu
TIAN Lei
LAN Liqiong
CHEN Hao
SUN Qun
GAO Peng
Effect of electron beam irradiation sterilization on the Tibetan medicine Bawei Chenxiang powder
Fushe yanjiu yu fushe gongyi xuebao
electron beam
irradiation sterilization
bawei chenxiang powder
total number of microorganisms
active ingredients
title Effect of electron beam irradiation sterilization on the Tibetan medicine Bawei Chenxiang powder
title_full Effect of electron beam irradiation sterilization on the Tibetan medicine Bawei Chenxiang powder
title_fullStr Effect of electron beam irradiation sterilization on the Tibetan medicine Bawei Chenxiang powder
title_full_unstemmed Effect of electron beam irradiation sterilization on the Tibetan medicine Bawei Chenxiang powder
title_short Effect of electron beam irradiation sterilization on the Tibetan medicine Bawei Chenxiang powder
title_sort effect of electron beam irradiation sterilization on the tibetan medicine bawei chenxiang powder
topic electron beam
irradiation sterilization
bawei chenxiang powder
total number of microorganisms
active ingredients
url http://www.fs.sinap.ac.cn/thesisDetails#10.11889/j.1000-3436.2022-0030&lang=zh
work_keys_str_mv AT dejizhuoga effectofelectronbeamirradiationsterilizationonthetibetanmedicinebaweichenxiangpowder
AT wangwei effectofelectronbeamirradiationsterilizationonthetibetanmedicinebaweichenxiangpowder
AT dejicuomu effectofelectronbeamirradiationsterilizationonthetibetanmedicinebaweichenxiangpowder
AT tianlei effectofelectronbeamirradiationsterilizationonthetibetanmedicinebaweichenxiangpowder
AT lanliqiong effectofelectronbeamirradiationsterilizationonthetibetanmedicinebaweichenxiangpowder
AT chenhao effectofelectronbeamirradiationsterilizationonthetibetanmedicinebaweichenxiangpowder
AT sunqun effectofelectronbeamirradiationsterilizationonthetibetanmedicinebaweichenxiangpowder
AT gaopeng effectofelectronbeamirradiationsterilizationonthetibetanmedicinebaweichenxiangpowder