?-Fluoro-Benzylphosphonates as Reagents for the Preparation of 1-Fluoro-1-Aryl Alkenes and ?-Fluorostilbenes
The preparation of several fluoro-benzylphosphonates Ar-CHF-PO(OEt)2 and their Wadsworth-Emmons type olefination with aldehydes and ketones are described affording fluorostyrenes and fluorostilbenes. Some of these compounds are incorporated into target molecules tested as drug candidates....
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | deu |
| Published: |
Swiss Chemical Society
2004-03-01
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| Series: | CHIMIA |
| Subjects: | |
| Online Access: | https://chimia.ch/chimia/article/view/3818 |
| _version_ | 1828125056317784064 |
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| author | Thomas Allmendinger Roger Fujimoto Fabrizio Gasparini Walter Schilling Yoshi Satoh |
| author_facet | Thomas Allmendinger Roger Fujimoto Fabrizio Gasparini Walter Schilling Yoshi Satoh |
| author_sort | Thomas Allmendinger |
| collection | DOAJ |
| description |
The preparation of several fluoro-benzylphosphonates Ar-CHF-PO(OEt)2 and their Wadsworth-Emmons type olefination with aldehydes and ketones are described affording fluorostyrenes and fluorostilbenes. Some of these compounds are incorporated into target molecules tested as
drug candidates.
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| first_indexed | 2024-04-11T15:14:47Z |
| format | Article |
| id | doaj.art-49c1bcbdadf747268c5edca61d30f79f |
| institution | Directory Open Access Journal |
| issn | 0009-4293 2673-2424 |
| language | deu |
| last_indexed | 2024-04-11T15:14:47Z |
| publishDate | 2004-03-01 |
| publisher | Swiss Chemical Society |
| record_format | Article |
| series | CHIMIA |
| spelling | doaj.art-49c1bcbdadf747268c5edca61d30f79f2022-12-22T04:16:31ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24242004-03-0158310.2533/000942904777678217?-Fluoro-Benzylphosphonates as Reagents for the Preparation of 1-Fluoro-1-Aryl Alkenes and ?-FluorostilbenesThomas AllmendingerRoger FujimotoFabrizio GaspariniWalter SchillingYoshi Satoh The preparation of several fluoro-benzylphosphonates Ar-CHF-PO(OEt)2 and their Wadsworth-Emmons type olefination with aldehydes and ketones are described affording fluorostyrenes and fluorostilbenes. Some of these compounds are incorporated into target molecules tested as drug candidates. https://chimia.ch/chimia/article/view/3818Fluoro-benzylphosphonatesFluoroolefinsHorner-wadsworth-emmons olefination |
| spellingShingle | Thomas Allmendinger Roger Fujimoto Fabrizio Gasparini Walter Schilling Yoshi Satoh ?-Fluoro-Benzylphosphonates as Reagents for the Preparation of 1-Fluoro-1-Aryl Alkenes and ?-Fluorostilbenes CHIMIA Fluoro-benzylphosphonates Fluoroolefins Horner-wadsworth-emmons olefination |
| title | ?-Fluoro-Benzylphosphonates as Reagents for the Preparation of 1-Fluoro-1-Aryl Alkenes and ?-Fluorostilbenes |
| title_full | ?-Fluoro-Benzylphosphonates as Reagents for the Preparation of 1-Fluoro-1-Aryl Alkenes and ?-Fluorostilbenes |
| title_fullStr | ?-Fluoro-Benzylphosphonates as Reagents for the Preparation of 1-Fluoro-1-Aryl Alkenes and ?-Fluorostilbenes |
| title_full_unstemmed | ?-Fluoro-Benzylphosphonates as Reagents for the Preparation of 1-Fluoro-1-Aryl Alkenes and ?-Fluorostilbenes |
| title_short | ?-Fluoro-Benzylphosphonates as Reagents for the Preparation of 1-Fluoro-1-Aryl Alkenes and ?-Fluorostilbenes |
| title_sort | fluoro benzylphosphonates as reagents for the preparation of 1 fluoro 1 aryl alkenes and fluorostilbenes |
| topic | Fluoro-benzylphosphonates Fluoroolefins Horner-wadsworth-emmons olefination |
| url | https://chimia.ch/chimia/article/view/3818 |
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