Kleine-levin syndrome: A rare case and review
Kleine–Levin syndrome (KLS), also known as sleeping beauty syndrome, is a rare disorder with unknown etiology. The syndrome is characterized by hypersomnolence and may be associated with hypersexuality, hyperphagia and cognitive or mood changes. Fever, head trauma and stress may be the precipitating...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2019-01-01
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| Series: | Annals of Indian Psychiatry |
| Subjects: | |
| Online Access: | http://www.anip.co.in/article.asp?issn=2588-8358;year=2019;volume=3;issue=1;spage=58;epage=59;aulast=Patel |
| _version_ | 1818530302391222272 |
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| author | Falguni B Patel Parlin M Dadhaniya Manasvi V Jariwala Bhaveshkumar M Lakdawala |
| author_facet | Falguni B Patel Parlin M Dadhaniya Manasvi V Jariwala Bhaveshkumar M Lakdawala |
| author_sort | Falguni B Patel |
| collection | DOAJ |
| description | Kleine–Levin syndrome (KLS), also known as sleeping beauty syndrome, is a rare disorder with unknown etiology. The syndrome is characterized by hypersomnolence and may be associated with hypersexuality, hyperphagia and cognitive or mood changes. Fever, head trauma and stress may be the precipitating factors. The case here is a 15-year-old male patient who presented with excessive sleepiness, hypersexual behavior, excessive food intake and mood changes. These symptoms started after becoming afebrile from high-grade fever. Multiple investigations done were within normal limits. He did not respond to valproate, olanzapine and lorazepam. Spontaneous remission and reemergence of symptoms after 2 weeks were noted. By clinical history, normal investigations and exclusion of other mental and medical disorders, he was diagnosed to have KLS. Reviewing literature, lithium therapy was found to be beneficial in KLS. Hence, lithium was given in this patient to which he responded well. |
| first_indexed | 2024-12-11T17:17:59Z |
| format | Article |
| id | doaj.art-49c328e4fd1946bdaed8e346f3e134a8 |
| institution | Directory Open Access Journal |
| issn | 2588-8358 2588-8366 |
| language | English |
| last_indexed | 2024-12-11T17:17:59Z |
| publishDate | 2019-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Annals of Indian Psychiatry |
| spelling | doaj.art-49c328e4fd1946bdaed8e346f3e134a82022-12-22T00:57:16ZengWolters Kluwer Medknow PublicationsAnnals of Indian Psychiatry2588-83582588-83662019-01-0131585910.4103/aip.aip_48_18Kleine-levin syndrome: A rare case and reviewFalguni B PatelParlin M DadhaniyaManasvi V JariwalaBhaveshkumar M LakdawalaKleine–Levin syndrome (KLS), also known as sleeping beauty syndrome, is a rare disorder with unknown etiology. The syndrome is characterized by hypersomnolence and may be associated with hypersexuality, hyperphagia and cognitive or mood changes. Fever, head trauma and stress may be the precipitating factors. The case here is a 15-year-old male patient who presented with excessive sleepiness, hypersexual behavior, excessive food intake and mood changes. These symptoms started after becoming afebrile from high-grade fever. Multiple investigations done were within normal limits. He did not respond to valproate, olanzapine and lorazepam. Spontaneous remission and reemergence of symptoms after 2 weeks were noted. By clinical history, normal investigations and exclusion of other mental and medical disorders, he was diagnosed to have KLS. Reviewing literature, lithium therapy was found to be beneficial in KLS. Hence, lithium was given in this patient to which he responded well.http://www.anip.co.in/article.asp?issn=2588-8358;year=2019;volume=3;issue=1;spage=58;epage=59;aulast=PatelHypersomnolenceKleine–Levin syndromelithiummood disturbance |
| spellingShingle | Falguni B Patel Parlin M Dadhaniya Manasvi V Jariwala Bhaveshkumar M Lakdawala Kleine-levin syndrome: A rare case and review Annals of Indian Psychiatry Hypersomnolence Kleine–Levin syndrome lithium mood disturbance |
| title | Kleine-levin syndrome: A rare case and review |
| title_full | Kleine-levin syndrome: A rare case and review |
| title_fullStr | Kleine-levin syndrome: A rare case and review |
| title_full_unstemmed | Kleine-levin syndrome: A rare case and review |
| title_short | Kleine-levin syndrome: A rare case and review |
| title_sort | kleine levin syndrome a rare case and review |
| topic | Hypersomnolence Kleine–Levin syndrome lithium mood disturbance |
| url | http://www.anip.co.in/article.asp?issn=2588-8358;year=2019;volume=3;issue=1;spage=58;epage=59;aulast=Patel |
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