On the TRAIL of Better Therapies: Understanding TNFRSF Structure-Function

On the TRAIL of Better Therapies: Understanding TNFRSF Structure-Function

Tumor necrosis factor (TNF) superfamily ligands show diverse biological functions, such as the induction of apoptotic cell death or cell survival and proliferation, making them excellent therapeutic targets for cancer and autoimmunity. We review the latest literature on TNF receptor superfamily sign...

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Bibliographic Details
Main Authors: Éva S. Vanamee, Denise L. Faustman
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cells
Subjects:
trail
trail receptors
apoptosis
tnfsf signaling
receptor clustering
antiparallel dimer
hexagonal lattice
cancer
Online Access:https://www.mdpi.com/2073-4409/9/3/764

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https://www.mdpi.com/2073-4409/9/3/764

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