Case-control study on relationship between diet quality and thyroid nodules
BackgroundBoth domestic and foreign studies on the diet quality of patients with thyroid nodules are rare at present, and the relationship between thyroid nodules and diet quality is still unclear.ObjectiveThis study aims to evaluate the diet quality of thyroid nodules with the China Healthy Diet In...
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| Format: | Article |
| Language: | English |
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Editorial Committee of Journal of Environmental and Occupational Medicine
2021-11-01
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| Series: | 环境与职业医学 |
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| Online Access: | http://www.jeom.org/article/cn/10.13213/j.cnki.jeom.2021.20603 |
| _version_ | 1819320231716192256 |
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| author | Wei ZHOU Zhengyuan WANG Qian XIA Xiaodong JIA Jiajie ZANG Xueying CUI Xiangting LI Changyi GUO fan WU |
| author_facet | Wei ZHOU Zhengyuan WANG Qian XIA Xiaodong JIA Jiajie ZANG Xueying CUI Xiangting LI Changyi GUO fan WU |
| author_sort | Wei ZHOU |
| collection | DOAJ |
| description | BackgroundBoth domestic and foreign studies on the diet quality of patients with thyroid nodules are rare at present, and the relationship between thyroid nodules and diet quality is still unclear.ObjectiveThis study aims to evaluate the diet quality of thyroid nodules with the China Healthy Diet Index (CHDI) and to explore the relationship between diet quality and thyroid nodules.MethodsWe conducted a hospital-based case-control study in which 387 patients with thyroid nodules were matched individually (1∶1) by gender and age (±3 years) to the controls who ordered a routine physical examine and with negative thyroid nodules reported by B-ultrasound in the same hospital. A structured questionnaire was applied to collect data on general characteristics and diet. CHDI was employed to evaluate the diet quality of the two groups. CHDI is based on the Dietary Guidelines for Chinese Residents and the recommended food intake in the balanced diet pagoda, combined with the dietary nutritional status of Chinese population. The index contains 13 scoring components, and the highest total score is 100, with a higher score representing better dietary quality. CHDI scores < 60, 60-<80, and ≥80 are recognized as unqualified, qualified, and good diet quality, respectively.ResultsThe scores of the thyroid nodule cases were lower than the scores of the controls in total vegetables, dark vegetables, fruits, and fish/shrimps (all Ps<0.05). The nonparametric test results found that there were significant differences in the distributions of scores in total vegetables, dark vegetables, fruits, soybeans, and fish/shrimps between the case and the control groups (all Ps<0.05). The percentages reaching the full scores in food variety, meat and eggs, and empty calories in both groups exceeded 60%, while the percentages reaching the full scores in whole grains/beans/tubers, dairy, soybeans, and sodium were lower than 30% in the two groups. The median CHDI scores of the thyroid nodule cases and the controls were 69.1 and 72.9, respectively; the cases' CHDI score was lower than the controls' (P<0.05). The proportions of unqualified diet in the case and the control groups accounted for 23.0% and 13.7% respectively (P=0.001). After being adjusted for education level, marital status, occupation, monthly household income per capita, body mass index, hypertension/diabetes, energy, and iodine intake, the results of logistic regression analysis showed that the risk for thyroid nodules was negatively associated with CHDI score (CHDI qualified group vs. CHDI unqualified group, OR=0.484, 95%CI: 0.291-0.804; CHDI good dietary quality group vs. CHDI unqualified group, OR=0.414, 95%CI: 0.230−0.746).ConclusionThe diet quality of patients with thyroid nodules is lower than that of the control group, as the former reported lower consumptions of total vegetables, dark vegetables, fruits, and fish/shrimps. Those who have good or qualified diet quality show a reduced risk of thyroid nodules than those with unqualified dietary quality. |
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| id | doaj.art-49c62db8deba4693ad5f2739d9e5660c |
| institution | Directory Open Access Journal |
| issn | 2095-9982 |
| language | English |
| last_indexed | 2024-12-24T11:16:18Z |
| publishDate | 2021-11-01 |
| publisher | Editorial Committee of Journal of Environmental and Occupational Medicine |
| record_format | Article |
| series | 环境与职业医学 |
| spelling | doaj.art-49c62db8deba4693ad5f2739d9e5660c2022-12-21T16:58:21ZengEditorial Committee of Journal of Environmental and Occupational Medicine环境与职业医学2095-99822021-11-0138111192119810.13213/j.cnki.jeom.2021.2060320603Case-control study on relationship between diet quality and thyroid nodulesWei ZHOU0Zhengyuan WANG1Qian XIA2Xiaodong JIA3Jiajie ZANG4Xueying CUI5Xiangting LI6Changyi GUO7fan WU8Department of School and Nutrition, Shanghai Yangpu District Center for Disease Control and Prevention, Shanghai 200090, ChinaShanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, ChinaDepartment of School and Nutrition, Shanghai Yangpu District Center for Disease Control and Prevention, Shanghai 200090, ChinaShanghai Chemical Industry Park Medical Center, Shanghai 201507, ChinaShanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, ChinaShanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, ChinaDepartment of School and Nutrition, Shanghai Yangpu District Center for Disease Control and Prevention, Shanghai 200090, ChinaShanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, ChinaShanghai Medical College of Fudan University, Shanghai 200032, ChinaBackgroundBoth domestic and foreign studies on the diet quality of patients with thyroid nodules are rare at present, and the relationship between thyroid nodules and diet quality is still unclear.ObjectiveThis study aims to evaluate the diet quality of thyroid nodules with the China Healthy Diet Index (CHDI) and to explore the relationship between diet quality and thyroid nodules.MethodsWe conducted a hospital-based case-control study in which 387 patients with thyroid nodules were matched individually (1∶1) by gender and age (±3 years) to the controls who ordered a routine physical examine and with negative thyroid nodules reported by B-ultrasound in the same hospital. A structured questionnaire was applied to collect data on general characteristics and diet. CHDI was employed to evaluate the diet quality of the two groups. CHDI is based on the Dietary Guidelines for Chinese Residents and the recommended food intake in the balanced diet pagoda, combined with the dietary nutritional status of Chinese population. The index contains 13 scoring components, and the highest total score is 100, with a higher score representing better dietary quality. CHDI scores < 60, 60-<80, and ≥80 are recognized as unqualified, qualified, and good diet quality, respectively.ResultsThe scores of the thyroid nodule cases were lower than the scores of the controls in total vegetables, dark vegetables, fruits, and fish/shrimps (all Ps<0.05). The nonparametric test results found that there were significant differences in the distributions of scores in total vegetables, dark vegetables, fruits, soybeans, and fish/shrimps between the case and the control groups (all Ps<0.05). The percentages reaching the full scores in food variety, meat and eggs, and empty calories in both groups exceeded 60%, while the percentages reaching the full scores in whole grains/beans/tubers, dairy, soybeans, and sodium were lower than 30% in the two groups. The median CHDI scores of the thyroid nodule cases and the controls were 69.1 and 72.9, respectively; the cases' CHDI score was lower than the controls' (P<0.05). The proportions of unqualified diet in the case and the control groups accounted for 23.0% and 13.7% respectively (P=0.001). After being adjusted for education level, marital status, occupation, monthly household income per capita, body mass index, hypertension/diabetes, energy, and iodine intake, the results of logistic regression analysis showed that the risk for thyroid nodules was negatively associated with CHDI score (CHDI qualified group vs. CHDI unqualified group, OR=0.484, 95%CI: 0.291-0.804; CHDI good dietary quality group vs. CHDI unqualified group, OR=0.414, 95%CI: 0.230−0.746).ConclusionThe diet quality of patients with thyroid nodules is lower than that of the control group, as the former reported lower consumptions of total vegetables, dark vegetables, fruits, and fish/shrimps. Those who have good or qualified diet quality show a reduced risk of thyroid nodules than those with unqualified dietary quality.http://www.jeom.org/article/cn/10.13213/j.cnki.jeom.2021.20603china healthy diet indexthyroid nodulescase-control studydiet quality |
| spellingShingle | Wei ZHOU Zhengyuan WANG Qian XIA Xiaodong JIA Jiajie ZANG Xueying CUI Xiangting LI Changyi GUO fan WU Case-control study on relationship between diet quality and thyroid nodules 环境与职业医学 china healthy diet index thyroid nodules case-control study diet quality |
| title | Case-control study on relationship between diet quality and thyroid nodules |
| title_full | Case-control study on relationship between diet quality and thyroid nodules |
| title_fullStr | Case-control study on relationship between diet quality and thyroid nodules |
| title_full_unstemmed | Case-control study on relationship between diet quality and thyroid nodules |
| title_short | Case-control study on relationship between diet quality and thyroid nodules |
| title_sort | case control study on relationship between diet quality and thyroid nodules |
| topic | china healthy diet index thyroid nodules case-control study diet quality |
| url | http://www.jeom.org/article/cn/10.13213/j.cnki.jeom.2021.20603 |
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