Can Anhedonia Be Considered a Suicide Risk Factor? A Review of the Literature

<i>Background and Objectives</i>: At present, data collected from the literature about suicide and anhedonia are controversial. Some studies have shown that low levels of anhedonia are associated with serious suicide attempts and death by suicide, while other studies have shown that high...

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Main Authors: Luca Bonanni, Flavia Gualtieri, David Lester, Giulia Falcone, Adele Nardella, Andrea Fiorillo, Maurizio Pompili
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1010-660X/55/8/458
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author Luca Bonanni
Flavia Gualtieri
David Lester
Giulia Falcone
Adele Nardella
Andrea Fiorillo
Maurizio Pompili
author_facet Luca Bonanni
Flavia Gualtieri
David Lester
Giulia Falcone
Adele Nardella
Andrea Fiorillo
Maurizio Pompili
author_sort Luca Bonanni
collection DOAJ
description <i>Background and Objectives</i>: At present, data collected from the literature about suicide and anhedonia are controversial. Some studies have shown that low levels of anhedonia are associated with serious suicide attempts and death by suicide, while other studies have shown that high levels of anhedonia are associated with suicide. <i>Materials and Methods</i>: For this review, we searched PubMed, Medline, and ScienceDirect for clinical studies published from 1 January 1990 to 31 December 2018 with the following search terms used in the title or in the abstract: &#8220;anhedonia AND suicid*.&#8221; We obtained a total of 155 articles; 133 items were excluded using specific exclusion criteria, the remaining 22 articles included were divided into six groups based on the psychiatric diagnosis: mood disorders, schizophrenia spectrum disorders, post-traumatic stress disorder (PTSD), other diagnoses, attempted suicides, and others (healthy subjects). <i>Results</i>: The results of this review reveal inconsistencies. Some studies reported that high anhedonia scores were associated with suicidal behavior (regardless of the diagnosis), while other studies found that low anhedonia scores were associated with suicidal behavior, and a few studies reported no association. The most consistent association between anhedonia and suicidal behavior was found for affective disorders (7 of 7 studies reported a significant positive association) and for PTSD (3 of 3 studies reported a positive association). In the two studies of patients with schizophrenia, one found no association, and one found a negative association. For patients who attempted suicide (undiagnosed), one study found a positive association, one a positive association only for depressed attempters, and one a negative association. <i>Conclusions</i>: We found the most consistent positive association for patients with affective disorders and PTSD, indicating that the assessment of anhedonia may be useful in the evaluation of suicidal risk.
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spelling doaj.art-49caeec879ff4317929b11fee1c0120f2023-09-03T05:01:48ZengMDPI AGMedicina1010-660X2019-08-0155845810.3390/medicina55080458medicina55080458Can Anhedonia Be Considered a Suicide Risk Factor? A Review of the LiteratureLuca Bonanni0Flavia Gualtieri1David Lester2Giulia Falcone3Adele Nardella4Andrea Fiorillo5Maurizio Pompili6Psychiatry Residency Training Program, Faculty of Medicine and Psychology, Sapienza University of Rome, 00189 Rome, ItalyPsychiatry Residency Training Program, Faculty of Medicine and Psychology, Sapienza University of Rome, 00189 Rome, ItalyPsychology Program, Stockton University, Galloway, NJ 08205, USAPsychiatry Residency Training Program, Faculty of Medicine and Psychology, Sapienza University of Rome, 00189 Rome, ItalyPsychiatry Residency Training Program, Faculty of Medicine and Psychology, Sapienza University of Rome, 00189 Rome, ItalyDepartment of Psychiatry, University of Campania Luigi Vanvitelli, 80138 Naples, ItalyDepartment of Neurosciences, Mental Health and Sensory Organs, Suicide Prevention Center, Sant’Andrea Hospital, Sapienza University of Rome, 00189 Rome, Italy<i>Background and Objectives</i>: At present, data collected from the literature about suicide and anhedonia are controversial. Some studies have shown that low levels of anhedonia are associated with serious suicide attempts and death by suicide, while other studies have shown that high levels of anhedonia are associated with suicide. <i>Materials and Methods</i>: For this review, we searched PubMed, Medline, and ScienceDirect for clinical studies published from 1 January 1990 to 31 December 2018 with the following search terms used in the title or in the abstract: &#8220;anhedonia AND suicid*.&#8221; We obtained a total of 155 articles; 133 items were excluded using specific exclusion criteria, the remaining 22 articles included were divided into six groups based on the psychiatric diagnosis: mood disorders, schizophrenia spectrum disorders, post-traumatic stress disorder (PTSD), other diagnoses, attempted suicides, and others (healthy subjects). <i>Results</i>: The results of this review reveal inconsistencies. Some studies reported that high anhedonia scores were associated with suicidal behavior (regardless of the diagnosis), while other studies found that low anhedonia scores were associated with suicidal behavior, and a few studies reported no association. The most consistent association between anhedonia and suicidal behavior was found for affective disorders (7 of 7 studies reported a significant positive association) and for PTSD (3 of 3 studies reported a positive association). In the two studies of patients with schizophrenia, one found no association, and one found a negative association. For patients who attempted suicide (undiagnosed), one study found a positive association, one a positive association only for depressed attempters, and one a negative association. <i>Conclusions</i>: We found the most consistent positive association for patients with affective disorders and PTSD, indicating that the assessment of anhedonia may be useful in the evaluation of suicidal risk.https://www.mdpi.com/1010-660X/55/8/458anhedoniaPTSDsuicidesuicide risksuicidal behavior
spellingShingle Luca Bonanni
Flavia Gualtieri
David Lester
Giulia Falcone
Adele Nardella
Andrea Fiorillo
Maurizio Pompili
Can Anhedonia Be Considered a Suicide Risk Factor? A Review of the Literature
Medicina
anhedonia
PTSD
suicide
suicide risk
suicidal behavior
title Can Anhedonia Be Considered a Suicide Risk Factor? A Review of the Literature
title_full Can Anhedonia Be Considered a Suicide Risk Factor? A Review of the Literature
title_fullStr Can Anhedonia Be Considered a Suicide Risk Factor? A Review of the Literature
title_full_unstemmed Can Anhedonia Be Considered a Suicide Risk Factor? A Review of the Literature
title_short Can Anhedonia Be Considered a Suicide Risk Factor? A Review of the Literature
title_sort can anhedonia be considered a suicide risk factor a review of the literature
topic anhedonia
PTSD
suicide
suicide risk
suicidal behavior
url https://www.mdpi.com/1010-660X/55/8/458
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