Рroblems of PCR diagnostics OF COVID-19
To date, an adequate and timely assessment of the number of cases is the basis of effective measures aimed at preventing the spread of COVID-19 infection. Real-time reverse transcription polymerase chain reaction (RT-PCR) remains the gold standard for confirming COVID-19.The purpose of the work: to...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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Journal Infectology
2022-10-01
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| Series: | Журнал инфектологии |
| Subjects: | |
| Online Access: | https://journal.niidi.ru/jofin/article/view/1398 |
| _version_ | 1826557765751930880 |
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| author | T. D. Grigorieva M. А. Belopolskaya |
| author_facet | T. D. Grigorieva M. А. Belopolskaya |
| author_sort | T. D. Grigorieva |
| collection | DOAJ |
| description | To date, an adequate and timely assessment of the number of cases is the basis of effective measures aimed at preventing the spread of COVID-19 infection. Real-time reverse transcription polymerase chain reaction (RT-PCR) remains the gold standard for confirming COVID-19.The purpose of the work: to analyze the experience of the city virological center of the S.P. Botkin Clinical Infectious Diseases Hospital (Botkin Hospital) for the examination for the presence of SARS-CoV-2 coronavirus by PCR in the period from 2020 to 2022.Materials and methods. The systematization of PCR studies on COVID-19 for the period 2020-2022 was carried out. A total of 221,901 people were examined, positive results were obtained in 55,372 (24.95%). Among the contingents of the examined patients, patients who underwent inpatient treatment at the Botkin Hospital.Conclusions. This study analyzed the possible causes of false-positive and false-negative PCR results. The correlation of the number of positive results with the dynamics of detection of new cases of COVID-19 in St. Petersburg during the 2020-2022 pandemic is shown. It has been established that the proportion of patients examined more than 3 times during the period of hospitalization remains significant. This fact requires the closest attention, given the high cost and laboriousness of PCR studies. |
| first_indexed | 2024-03-12T03:07:58Z |
| format | Article |
| id | doaj.art-49cddd284b654e5c9c161f1e5d3c9473 |
| institution | Directory Open Access Journal |
| issn | 2072-6732 |
| language | Russian |
| last_indexed | 2025-03-14T08:33:48Z |
| publishDate | 2022-10-01 |
| publisher | Journal Infectology |
| record_format | Article |
| series | Журнал инфектологии |
| spelling | doaj.art-49cddd284b654e5c9c161f1e5d3c94732025-03-02T13:00:35ZrusJournal InfectologyЖурнал инфектологии2072-67322022-10-01143556010.22625/2072-6732-2022-14-3-55-601026Рroblems of PCR diagnostics OF COVID-19T. D. Grigorieva0M. А. Belopolskaya1Clinical Infectious Diseases Hospital named after S.P. BotkinClinical Infectious Diseases Hospital named after S.P. Botkin; Institute of Experimental MedicineTo date, an adequate and timely assessment of the number of cases is the basis of effective measures aimed at preventing the spread of COVID-19 infection. Real-time reverse transcription polymerase chain reaction (RT-PCR) remains the gold standard for confirming COVID-19.The purpose of the work: to analyze the experience of the city virological center of the S.P. Botkin Clinical Infectious Diseases Hospital (Botkin Hospital) for the examination for the presence of SARS-CoV-2 coronavirus by PCR in the period from 2020 to 2022.Materials and methods. The systematization of PCR studies on COVID-19 for the period 2020-2022 was carried out. A total of 221,901 people were examined, positive results were obtained in 55,372 (24.95%). Among the contingents of the examined patients, patients who underwent inpatient treatment at the Botkin Hospital.Conclusions. This study analyzed the possible causes of false-positive and false-negative PCR results. The correlation of the number of positive results with the dynamics of detection of new cases of COVID-19 in St. Petersburg during the 2020-2022 pandemic is shown. It has been established that the proportion of patients examined more than 3 times during the period of hospitalization remains significant. This fact requires the closest attention, given the high cost and laboriousness of PCR studies.https://journal.niidi.ru/jofin/article/view/1398covid-19sars-cov-2pcr |
| spellingShingle | T. D. Grigorieva M. А. Belopolskaya Рroblems of PCR diagnostics OF COVID-19 Журнал инфектологии covid-19 sars-cov-2 pcr |
| title | Рroblems of PCR diagnostics OF COVID-19 |
| title_full | Рroblems of PCR diagnostics OF COVID-19 |
| title_fullStr | Рroblems of PCR diagnostics OF COVID-19 |
| title_full_unstemmed | Рroblems of PCR diagnostics OF COVID-19 |
| title_short | Рroblems of PCR diagnostics OF COVID-19 |
| title_sort | рroblems of pcr diagnostics of covid 19 |
| topic | covid-19 sars-cov-2 pcr |
| url | https://journal.niidi.ru/jofin/article/view/1398 |
| work_keys_str_mv | AT tdgrigorieva rroblemsofpcrdiagnosticsofcovid19 AT mabelopolskaya rroblemsofpcrdiagnosticsofcovid19 |