Psychoactive substances in natural and unnatural deaths in Norway and Sweden – a study on victims of suicide and accidents compared with natural deaths in psychiatric patients

Abstract Background The extent of post-mortem detection of specific psychoactive drugs may differ between countries, and may greatly influence the national death register’s classification of manner and cause of death. The main objective of the present study was to analyse the magnitude and pattern o...

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Main Authors: Ida Kathrine Gravensteen, Øivind Ekeberg, Ingemar Thiblin, Karin Helweg-Larsen, Erlend Hem, Sidsel Rogde, Ingvild Maria Tøllefsen
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Psychiatry
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12888-019-2015-9
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author Ida Kathrine Gravensteen
Øivind Ekeberg
Ingemar Thiblin
Karin Helweg-Larsen
Erlend Hem
Sidsel Rogde
Ingvild Maria Tøllefsen
author_facet Ida Kathrine Gravensteen
Øivind Ekeberg
Ingemar Thiblin
Karin Helweg-Larsen
Erlend Hem
Sidsel Rogde
Ingvild Maria Tøllefsen
author_sort Ida Kathrine Gravensteen
collection DOAJ
description Abstract Background The extent of post-mortem detection of specific psychoactive drugs may differ between countries, and may greatly influence the national death register’s classification of manner and cause of death. The main objective of the present study was to analyse the magnitude and pattern of post-mortem detection of various psychoactive substances by the manner of death (suicide, accidental, undetermined and natural death with a psychiatric diagnosis) in Norway and Sweden. Methods The Cause of Death Registers in Norway and Sweden provided data on 600 deaths in 2008 from each country, of which 200 were registered as suicides, 200 as accidents or undetermined manner of death and 200 as natural deaths in individuals with a diagnosis of mental disorder as the underlying cause of death. We examined death certificates and forensic reports including toxicological analyses. Results The detection of psychoactive substances was commonly reported in suicides (66 and 74% in Norway and Sweden respectively), accidents (85 and 66%), undetermined manner of deaths (80% in the Swedish dataset) and in natural deaths with a psychiatric diagnosis (50 and 53%). Ethanol was the most commonly reported substance in the three manners of death, except from opioids being more common in accidental deaths in the Norwegian dataset. In cases of suicide by poisoning, benzodiazepines and z-drugs were the most common substances in both countries. Heroin or morphine was the most commonly reported substance in cases of accidental death by poisoning in the Norwegian dataset, while other opioids dominated the Swedish dataset. Anti-depressants were found in 22% of the suicide cases in the Norwegian dataset and in 29% of suicide cases in the Swedish dataset. Conclusions Psychoactive substances were detected in 66 and 74% of suicides and in 85 and 66% of accidental deaths in the Norwegian and Swedish datasets, respectively. Apart from a higher detection rate of heroin in deaths by accident in Norway than in Sweden, the pattern of detected psychoactive substances was similar in the two countries. Assessment of a suicidal motive may be hampered by the common use of psychoactive substances in suicide victims.
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spelling doaj.art-49d0493595074730b731a1060d99c8cc2022-12-21T19:09:27ZengBMCBMC Psychiatry1471-244X2019-01-011911910.1186/s12888-019-2015-9Psychoactive substances in natural and unnatural deaths in Norway and Sweden – a study on victims of suicide and accidents compared with natural deaths in psychiatric patientsIda Kathrine Gravensteen0Øivind Ekeberg1Ingemar Thiblin2Karin Helweg-Larsen3Erlend Hem4Sidsel Rogde5Ingvild Maria Tøllefsen6Department of Forensic Sciences, Oslo University HospitalDepartment of Behavioural Sciences in Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, University of OsloDepartment of Surgical Sciences, Uppsala UniversityDepartment of Social Medicine, University of CopenhagenDepartment of Behavioural Sciences in Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, University of OsloDepartment of Forensic Sciences, Oslo University HospitalDivision of Medicine, Department of Acute Medicine, Oslo University Hospital UllevaalAbstract Background The extent of post-mortem detection of specific psychoactive drugs may differ between countries, and may greatly influence the national death register’s classification of manner and cause of death. The main objective of the present study was to analyse the magnitude and pattern of post-mortem detection of various psychoactive substances by the manner of death (suicide, accidental, undetermined and natural death with a psychiatric diagnosis) in Norway and Sweden. Methods The Cause of Death Registers in Norway and Sweden provided data on 600 deaths in 2008 from each country, of which 200 were registered as suicides, 200 as accidents or undetermined manner of death and 200 as natural deaths in individuals with a diagnosis of mental disorder as the underlying cause of death. We examined death certificates and forensic reports including toxicological analyses. Results The detection of psychoactive substances was commonly reported in suicides (66 and 74% in Norway and Sweden respectively), accidents (85 and 66%), undetermined manner of deaths (80% in the Swedish dataset) and in natural deaths with a psychiatric diagnosis (50 and 53%). Ethanol was the most commonly reported substance in the three manners of death, except from opioids being more common in accidental deaths in the Norwegian dataset. In cases of suicide by poisoning, benzodiazepines and z-drugs were the most common substances in both countries. Heroin or morphine was the most commonly reported substance in cases of accidental death by poisoning in the Norwegian dataset, while other opioids dominated the Swedish dataset. Anti-depressants were found in 22% of the suicide cases in the Norwegian dataset and in 29% of suicide cases in the Swedish dataset. Conclusions Psychoactive substances were detected in 66 and 74% of suicides and in 85 and 66% of accidental deaths in the Norwegian and Swedish datasets, respectively. Apart from a higher detection rate of heroin in deaths by accident in Norway than in Sweden, the pattern of detected psychoactive substances was similar in the two countries. Assessment of a suicidal motive may be hampered by the common use of psychoactive substances in suicide victims.http://link.springer.com/article/10.1186/s12888-019-2015-9Accidental deathsNatural deathsPsychoactive substancesSuicide
spellingShingle Ida Kathrine Gravensteen
Øivind Ekeberg
Ingemar Thiblin
Karin Helweg-Larsen
Erlend Hem
Sidsel Rogde
Ingvild Maria Tøllefsen
Psychoactive substances in natural and unnatural deaths in Norway and Sweden – a study on victims of suicide and accidents compared with natural deaths in psychiatric patients
BMC Psychiatry
Accidental deaths
Natural deaths
Psychoactive substances
Suicide
title Psychoactive substances in natural and unnatural deaths in Norway and Sweden – a study on victims of suicide and accidents compared with natural deaths in psychiatric patients
title_full Psychoactive substances in natural and unnatural deaths in Norway and Sweden – a study on victims of suicide and accidents compared with natural deaths in psychiatric patients
title_fullStr Psychoactive substances in natural and unnatural deaths in Norway and Sweden – a study on victims of suicide and accidents compared with natural deaths in psychiatric patients
title_full_unstemmed Psychoactive substances in natural and unnatural deaths in Norway and Sweden – a study on victims of suicide and accidents compared with natural deaths in psychiatric patients
title_short Psychoactive substances in natural and unnatural deaths in Norway and Sweden – a study on victims of suicide and accidents compared with natural deaths in psychiatric patients
title_sort psychoactive substances in natural and unnatural deaths in norway and sweden a study on victims of suicide and accidents compared with natural deaths in psychiatric patients
topic Accidental deaths
Natural deaths
Psychoactive substances
Suicide
url http://link.springer.com/article/10.1186/s12888-019-2015-9
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