Testing for Coccidioidomycosis among Patients with Community-Acquired Pneumonia
Coccidioidomycosis is a common cause of community-acquired pneumonia (CAP) in disease-endemic areas. Because testing rates influence interpretation of reportable-disease data and quality of CAP patient care, we determined the proportion of CAP patients who were tested for Coccidioides spp., identifi...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2008-07-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/14/7/07-0832_article |
| _version_ | 1819207441030578176 |
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| author | Douglas C. Chang Shoana Anderson Kathleen Wannemuehler David M. Engelthaler Laura Erhart Rebecca H. Sunenshine Lauren A. Burwell Benjamin J. Park |
| author_facet | Douglas C. Chang Shoana Anderson Kathleen Wannemuehler David M. Engelthaler Laura Erhart Rebecca H. Sunenshine Lauren A. Burwell Benjamin J. Park |
| author_sort | Douglas C. Chang |
| collection | DOAJ |
| description | Coccidioidomycosis is a common cause of community-acquired pneumonia (CAP) in disease-endemic areas. Because testing rates influence interpretation of reportable-disease data and quality of CAP patient care, we determined the proportion of CAP patients who were tested for Coccidioides spp., identified testing predictors, and determined the proportion of tested patients who had positive coccidioidomycosis results. Cohort studies to determine the proportion of ambulatory CAP patients who were tested in 2 healthcare systems in metropolitan Phoenix found testing rates of 2% and 13%. A case-control study identified significant predictors of testing to be age >18 years, rash, chest pain, and symptoms for >14 days. Serologic testing confirmed coccidioidomycosis in 9 (15%) of 60 tested patients, suggesting that the proportion of CAP caused by coccidioidomycosis was substantial. However, because Coccidioides spp. testing among CAP patients was infrequent, reportable-disease data, which rely on positive diagnostic test results, greatly underestimate the true disease prevalence. |
| first_indexed | 2024-12-23T05:23:32Z |
| format | Article |
| id | doaj.art-49d0cd4ba49b44c3800c60a64919242e |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-23T05:23:32Z |
| publishDate | 2008-07-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-49d0cd4ba49b44c3800c60a64919242e2022-12-21T17:58:39ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592008-07-011471053105910.3201/eid1407.070832Testing for Coccidioidomycosis among Patients with Community-Acquired PneumoniaDouglas C. ChangShoana AndersonKathleen WannemuehlerDavid M. EngelthalerLaura ErhartRebecca H. SunenshineLauren A. BurwellBenjamin J. ParkCoccidioidomycosis is a common cause of community-acquired pneumonia (CAP) in disease-endemic areas. Because testing rates influence interpretation of reportable-disease data and quality of CAP patient care, we determined the proportion of CAP patients who were tested for Coccidioides spp., identified testing predictors, and determined the proportion of tested patients who had positive coccidioidomycosis results. Cohort studies to determine the proportion of ambulatory CAP patients who were tested in 2 healthcare systems in metropolitan Phoenix found testing rates of 2% and 13%. A case-control study identified significant predictors of testing to be age >18 years, rash, chest pain, and symptoms for >14 days. Serologic testing confirmed coccidioidomycosis in 9 (15%) of 60 tested patients, suggesting that the proportion of CAP caused by coccidioidomycosis was substantial. However, because Coccidioides spp. testing among CAP patients was infrequent, reportable-disease data, which rely on positive diagnostic test results, greatly underestimate the true disease prevalence.https://wwwnc.cdc.gov/eid/article/14/7/07-0832_articleCoccidioidomycosispneumoniaserologyresearchUnited States |
| spellingShingle | Douglas C. Chang Shoana Anderson Kathleen Wannemuehler David M. Engelthaler Laura Erhart Rebecca H. Sunenshine Lauren A. Burwell Benjamin J. Park Testing for Coccidioidomycosis among Patients with Community-Acquired Pneumonia Emerging Infectious Diseases Coccidioidomycosis pneumonia serology research United States |
| title | Testing for Coccidioidomycosis among Patients with Community-Acquired Pneumonia |
| title_full | Testing for Coccidioidomycosis among Patients with Community-Acquired Pneumonia |
| title_fullStr | Testing for Coccidioidomycosis among Patients with Community-Acquired Pneumonia |
| title_full_unstemmed | Testing for Coccidioidomycosis among Patients with Community-Acquired Pneumonia |
| title_short | Testing for Coccidioidomycosis among Patients with Community-Acquired Pneumonia |
| title_sort | testing for coccidioidomycosis among patients with community acquired pneumonia |
| topic | Coccidioidomycosis pneumonia serology research United States |
| url | https://wwwnc.cdc.gov/eid/article/14/7/07-0832_article |
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