THE SIGNIFICANCE OF QUANTITIES DETECTION OF СORE ANTIGEN IN BLOOD SERUM OF CHILDREN WITH HEPATITIS C
The clinical and pathogenetic significance of determining HCV core-antigen (HCV core-Ag) in serum of children with hepatitis C was investigated firstly. A direct correlation between the concentration of HCV core-Ag and viral load (VL) was revealed (r = 0,91). Children with high core-Ag (above 2500 f...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | Russian |
Published: |
LLC "Diagnostics and Vaccines"
2015-08-01
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Series: | Детские инфекции (Москва) |
Subjects: | |
Online Access: | https://detinf.elpub.ru/jour/article/view/18 |
Summary: | The clinical and pathogenetic significance of determining HCV core-antigen (HCV core-Ag) in serum of children with hepatitis C was investigated firstly. A direct correlation between the concentration of HCV core-Ag and viral load (VL) was revealed (r = 0,91). Children with high core-Ag (above 2500 fmol/L) showed indirect evidence for the immunosuppressive action of HCV core-Ag and occurrence of liver fibrosis more frequent (p < 0,05). In this grouP of children the prevalence of HCV subtype 3a was revealed (p < 0,05). |
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ISSN: | 2072-8107 |