Frosted branch angiitis after smallpox vaccination

Purpose: To describe a patient presenting with frosted branch angiitis soon after small-pox vaccination. Observations: Frosted branch angiitis (FBA) is an acute onset retinal vasculitis featuring prominent perivascular sheathing in otherwise healthy individuals. FBA has been associated with noninfec...

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Main Authors: Kristen Collister, Sam S. Dahr
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:American Journal of Ophthalmology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2451993622003681
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author Kristen Collister
Sam S. Dahr
author_facet Kristen Collister
Sam S. Dahr
author_sort Kristen Collister
collection DOAJ
description Purpose: To describe a patient presenting with frosted branch angiitis soon after small-pox vaccination. Observations: Frosted branch angiitis (FBA) is an acute onset retinal vasculitis featuring prominent perivascular sheathing in otherwise healthy individuals. FBA has been associated with noninfectious and infectious etiologies. This report describes a twenty-year-old African American female who developed bilateral frosted branch angiitis one week after small-pox vaccination. At presentation, the patient had bilateral, para-central visual field defects and subjective visual disturbances. On dilated exam, the patient demonstrated diffuse vasculitis bilaterally. The patient's field defects and clinical exam responded dramatically to oral prednisone therapy. Conclusions and Importance: Acute idiopathic frosted branch angiitis is a rare condition which was temporally associated with small-pox vaccination.
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spelling doaj.art-49d5b2f69a5b4749a23e4a1b263952572022-12-22T04:03:16ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362022-09-0127101622Frosted branch angiitis after smallpox vaccinationKristen Collister0Sam S. Dahr1Dean McGee Eye Institute, Oklahoma University Health Science Center, Oklahoma City, OK, USADean McGee Eye Institute, Oklahoma University Health Science Center, Oklahoma City, OK, USA; Corresponding author. Dean McGee Eye Institute, University of Oklahoma Health Sciences Center, 608 Stanton L Young Blvd , Oklahoma City, Oklahoma, 73104, USA.Purpose: To describe a patient presenting with frosted branch angiitis soon after small-pox vaccination. Observations: Frosted branch angiitis (FBA) is an acute onset retinal vasculitis featuring prominent perivascular sheathing in otherwise healthy individuals. FBA has been associated with noninfectious and infectious etiologies. This report describes a twenty-year-old African American female who developed bilateral frosted branch angiitis one week after small-pox vaccination. At presentation, the patient had bilateral, para-central visual field defects and subjective visual disturbances. On dilated exam, the patient demonstrated diffuse vasculitis bilaterally. The patient's field defects and clinical exam responded dramatically to oral prednisone therapy. Conclusions and Importance: Acute idiopathic frosted branch angiitis is a rare condition which was temporally associated with small-pox vaccination.http://www.sciencedirect.com/science/article/pii/S2451993622003681Smallpox vaccineRetinal vasculitisFrosted branch angiitisUveitisInflammation
spellingShingle Kristen Collister
Sam S. Dahr
Frosted branch angiitis after smallpox vaccination
American Journal of Ophthalmology Case Reports
Smallpox vaccine
Retinal vasculitis
Frosted branch angiitis
Uveitis
Inflammation
title Frosted branch angiitis after smallpox vaccination
title_full Frosted branch angiitis after smallpox vaccination
title_fullStr Frosted branch angiitis after smallpox vaccination
title_full_unstemmed Frosted branch angiitis after smallpox vaccination
title_short Frosted branch angiitis after smallpox vaccination
title_sort frosted branch angiitis after smallpox vaccination
topic Smallpox vaccine
Retinal vasculitis
Frosted branch angiitis
Uveitis
Inflammation
url http://www.sciencedirect.com/science/article/pii/S2451993622003681
work_keys_str_mv AT kristencollister frostedbranchangiitisaftersmallpoxvaccination
AT samsdahr frostedbranchangiitisaftersmallpoxvaccination