Accounting for cell type hierarchy in evaluating single cell RNA-seq clustering

Accounting for cell type hierarchy in evaluating single cell RNA-seq clustering

Abstract Cell clustering is one of the most common routines in single cell RNA-seq data analyses, for which a number of specialized methods are available. The evaluation of these methods ignores an important biological characteristic that the structure for a population of cells is hierarchical, whic...

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Bibliographic Details
Main Authors:	Zhijin Wu, Hao Wu
Format:	Article
Language:	English
Published:	BMC 2020-05-01
Series:	Genome Biology
Subjects:	Gene expression Single cell RNA-seq Clustering
Online Access:	http://link.springer.com/article/10.1186/s13059-020-02027-x

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