Touch Biopsy: A Simple and Rapid Method for the Diagnosis of Systemic Mycoses with Skin Dissemination in HIV-Infected Patients

Systemic fungal infection can disseminate to the skin and require prompt treatment, making early diagnosis very important. This study describes the use of a simple, quick touch biopsy method for the diagnosis of invasive mycoses in patients with AIDS with cutaneous manifestations. We identified...

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Main Authors: Retno Wahyuningsih, Robiatul Adawiyah, Aida SD Hoemardani, Ridhawati Sjam, Evy Yunihastuti, Darma Imran, Eliza Miranda, Samsuridjal Djauzi, Mulyati Tugiran, Ariananda Hariadi, Sem Samuel Surja
Format: Article
Language:English
Published: Universitas Indonesia 2021-04-01
Series:International Journal of Technology
Subjects:
Online Access:https://ijtech.eng.ui.ac.id/article/view/4297
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author Retno Wahyuningsih
Robiatul Adawiyah
Aida SD Hoemardani
Ridhawati Sjam
Evy Yunihastuti
Darma Imran
Eliza Miranda
Samsuridjal Djauzi
Mulyati Tugiran
Ariananda Hariadi
Sem Samuel Surja
author_facet Retno Wahyuningsih
Robiatul Adawiyah
Aida SD Hoemardani
Ridhawati Sjam
Evy Yunihastuti
Darma Imran
Eliza Miranda
Samsuridjal Djauzi
Mulyati Tugiran
Ariananda Hariadi
Sem Samuel Surja
author_sort Retno Wahyuningsih
collection DOAJ
description Systemic fungal infection can disseminate to the skin and require prompt treatment, making early diagnosis very important. This study describes the use of a simple, quick touch biopsy method for the diagnosis of invasive mycoses in patients with AIDS with cutaneous manifestations. We identified fungal infections in 24 of the 29 investigated patients. Histoplasma capsulatum, Cryptococcus neoformans, Talaromyces artroroseus, Aspergillus flavus, Candida tropicalis, and Malassezia sp. were visualized directly in samples obtained from cutaneous lesions and confirmed by culture and molecular examination. The results suggested that touch biopsy is a simple, rapid method for the diagnosis of systemic mycoses with skin dissemination. It can be performed using simple tools and provides quick results, allowing for early intervention with appropriate antifungal therapy.
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spelling doaj.art-49d8cc7aab9344dcb5462c4cb6a11e462023-01-02T03:37:55ZengUniversitas IndonesiaInternational Journal of Technology2086-96142087-21002021-04-0112224325110.14716/ijtech.v12i2.42974297Touch Biopsy: A Simple and Rapid Method for the Diagnosis of Systemic Mycoses with Skin Dissemination in HIV-Infected PatientsRetno Wahyuningsih0Robiatul Adawiyah1Aida SD Hoemardani2Ridhawati Sjam3Evy Yunihastuti4Darma Imran5Eliza Miranda6Samsuridjal Djauzi7Mulyati Tugiran8Ariananda Hariadi9Sem Samuel Surja101. Department of Parasitology, Faculty of Medicine Universitas Indonesia, Salemba Raya Street No.6, Jakarta 10430, Indonesia 2. Department of Parasitology, School of Medicine, Indonesian Christian UnDepartment of Parasitology, Faculty of Medicine Universitas Indonesia, Salemba Raya Street No.6, Jakarta 10430, IndonesiaIndonesia Dharmais Cancer Hospital, S. Parman Street Kav. 84-86, Jakarta 11420, IndonesiaDepartment of Parasitology, Faculty of Medicine Universitas Indonesia, Salemba Raya Street No.6, Jakarta 10430, IndonesiaDepartment of Internal Medicine Faculty of Medicine, Universitas Indonesia/ Cipto Mangunkusumo Hospital, Salemba raya street No.6, Jakarta 10430, IndonesiaDepartment of Neurology, Faculty of Medicine, Universitas Indonesia/ Cipto Mangunkusumo Hospital, Salemba Raya Street No.6, Jakarta 10430, IndonesiaDepartment of Dermato-Venereology, Faculty of Medicine, Universitas Indonesia/ Cipto Mangunkusumo Hospital, Salemba Raya Street No.6, Jakarta 10430, IndonesiaDepartment of Internal Medicine Faculty of Medicine, Universitas Indonesia/ Cipto Mangunkusumo Hospital, Salemba raya street No.6, Jakarta 10430, IndonesiaDepartment of Parasitology, Faculty of Medicine Universitas Indonesia, Salemba Raya Street No.6, Jakarta 10430, IndonesiaDepartment of Parasitology, Faculty of Medicine Universitas Indonesia, Salemba Raya Street No.6, Jakarta 10430, IndonesiaDepartment of Parasitology, School of Medicine and Health Sciences, Universitas Katolik Indonesia Atma Jaya, Jl. Pluit Raya No. 2, Jakarta Utara 14440, IndonesiaSystemic fungal infection can disseminate to the skin and require prompt treatment, making early diagnosis very important. This study describes the use of a simple, quick touch biopsy method for the diagnosis of invasive mycoses in patients with AIDS with cutaneous manifestations. We identified fungal infections in 24 of the 29 investigated patients. Histoplasma capsulatum, Cryptococcus neoformans, Talaromyces artroroseus, Aspergillus flavus, Candida tropicalis, and Malassezia sp. were visualized directly in samples obtained from cutaneous lesions and confirmed by culture and molecular examination. The results suggested that touch biopsy is a simple, rapid method for the diagnosis of systemic mycoses with skin dissemination. It can be performed using simple tools and provides quick results, allowing for early intervention with appropriate antifungal therapy.https://ijtech.eng.ui.ac.id/article/view/4297cutaneous disseminationrapid diagnosissystemic fungal infection
spellingShingle Retno Wahyuningsih
Robiatul Adawiyah
Aida SD Hoemardani
Ridhawati Sjam
Evy Yunihastuti
Darma Imran
Eliza Miranda
Samsuridjal Djauzi
Mulyati Tugiran
Ariananda Hariadi
Sem Samuel Surja
Touch Biopsy: A Simple and Rapid Method for the Diagnosis of Systemic Mycoses with Skin Dissemination in HIV-Infected Patients
International Journal of Technology
cutaneous dissemination
rapid diagnosis
systemic fungal infection
title Touch Biopsy: A Simple and Rapid Method for the Diagnosis of Systemic Mycoses with Skin Dissemination in HIV-Infected Patients
title_full Touch Biopsy: A Simple and Rapid Method for the Diagnosis of Systemic Mycoses with Skin Dissemination in HIV-Infected Patients
title_fullStr Touch Biopsy: A Simple and Rapid Method for the Diagnosis of Systemic Mycoses with Skin Dissemination in HIV-Infected Patients
title_full_unstemmed Touch Biopsy: A Simple and Rapid Method for the Diagnosis of Systemic Mycoses with Skin Dissemination in HIV-Infected Patients
title_short Touch Biopsy: A Simple and Rapid Method for the Diagnosis of Systemic Mycoses with Skin Dissemination in HIV-Infected Patients
title_sort touch biopsy a simple and rapid method for the diagnosis of systemic mycoses with skin dissemination in hiv infected patients
topic cutaneous dissemination
rapid diagnosis
systemic fungal infection
url https://ijtech.eng.ui.ac.id/article/view/4297
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