A Versatile Strategy for Surface Functionalization of Hydrophobic Nanoparticle by Boronic Acid Modified Polymerizable Diacetylene Derivatives
The flourishing advancements in nanotechnology significantly boost their application in biomedical fields. Whereas, inorganic nanomaterials are normally prepared and capped with hydrophobic ligands, which require essential surface modification to increase their biocompatibility and endow extra funct...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2019-11-01
|
| Series: | Frontiers in Chemistry |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fchem.2019.00734/full |
| _version_ | 1818987994077462528 |
|---|---|
| author | Shiwei Gu Chang Guo Hui Wang Guangjun Tian Suying Xu Leyu Wang |
| author_facet | Shiwei Gu Chang Guo Hui Wang Guangjun Tian Suying Xu Leyu Wang |
| author_sort | Shiwei Gu |
| collection | DOAJ |
| description | The flourishing advancements in nanotechnology significantly boost their application in biomedical fields. Whereas, inorganic nanomaterials are normally prepared and capped with hydrophobic ligands, which require essential surface modification to increase their biocompatibility and endow extra functions. Phenylboronic acid derivatives have long been known for its capacity for selective recognition of saccharides. Herein, we demonstrated a versatile surface modification strategy to directly convert hydrophobic inorganic nanocrystals into water-dispersible and targeting nanocomposites by employing boronic acid modified photo-polymerizable 10,12-pentacosadiynoicacid and further explore its potentials in selective cancer cell imaging. |
| first_indexed | 2024-12-20T19:15:31Z |
| format | Article |
| id | doaj.art-49e4ec32259549b6b46d24a13592497b |
| institution | Directory Open Access Journal |
| issn | 2296-2646 |
| language | English |
| last_indexed | 2024-12-20T19:15:31Z |
| publishDate | 2019-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Chemistry |
| spelling | doaj.art-49e4ec32259549b6b46d24a13592497b2022-12-21T19:29:08ZengFrontiers Media S.A.Frontiers in Chemistry2296-26462019-11-01710.3389/fchem.2019.00734492784A Versatile Strategy for Surface Functionalization of Hydrophobic Nanoparticle by Boronic Acid Modified Polymerizable Diacetylene DerivativesShiwei GuChang GuoHui WangGuangjun TianSuying XuLeyu WangThe flourishing advancements in nanotechnology significantly boost their application in biomedical fields. Whereas, inorganic nanomaterials are normally prepared and capped with hydrophobic ligands, which require essential surface modification to increase their biocompatibility and endow extra functions. Phenylboronic acid derivatives have long been known for its capacity for selective recognition of saccharides. Herein, we demonstrated a versatile surface modification strategy to directly convert hydrophobic inorganic nanocrystals into water-dispersible and targeting nanocomposites by employing boronic acid modified photo-polymerizable 10,12-pentacosadiynoicacid and further explore its potentials in selective cancer cell imaging.https://www.frontiersin.org/article/10.3389/fchem.2019.00734/fullboronic acidphoto polymerizationsurface functionalizationcancer cell targetingfluorescence imaging |
| spellingShingle | Shiwei Gu Chang Guo Hui Wang Guangjun Tian Suying Xu Leyu Wang A Versatile Strategy for Surface Functionalization of Hydrophobic Nanoparticle by Boronic Acid Modified Polymerizable Diacetylene Derivatives Frontiers in Chemistry boronic acid photo polymerization surface functionalization cancer cell targeting fluorescence imaging |
| title | A Versatile Strategy for Surface Functionalization of Hydrophobic Nanoparticle by Boronic Acid Modified Polymerizable Diacetylene Derivatives |
| title_full | A Versatile Strategy for Surface Functionalization of Hydrophobic Nanoparticle by Boronic Acid Modified Polymerizable Diacetylene Derivatives |
| title_fullStr | A Versatile Strategy for Surface Functionalization of Hydrophobic Nanoparticle by Boronic Acid Modified Polymerizable Diacetylene Derivatives |
| title_full_unstemmed | A Versatile Strategy for Surface Functionalization of Hydrophobic Nanoparticle by Boronic Acid Modified Polymerizable Diacetylene Derivatives |
| title_short | A Versatile Strategy for Surface Functionalization of Hydrophobic Nanoparticle by Boronic Acid Modified Polymerizable Diacetylene Derivatives |
| title_sort | versatile strategy for surface functionalization of hydrophobic nanoparticle by boronic acid modified polymerizable diacetylene derivatives |
| topic | boronic acid photo polymerization surface functionalization cancer cell targeting fluorescence imaging |
| url | https://www.frontiersin.org/article/10.3389/fchem.2019.00734/full |
| work_keys_str_mv | AT shiweigu aversatilestrategyforsurfacefunctionalizationofhydrophobicnanoparticlebyboronicacidmodifiedpolymerizablediacetylenederivatives AT changguo aversatilestrategyforsurfacefunctionalizationofhydrophobicnanoparticlebyboronicacidmodifiedpolymerizablediacetylenederivatives AT huiwang aversatilestrategyforsurfacefunctionalizationofhydrophobicnanoparticlebyboronicacidmodifiedpolymerizablediacetylenederivatives AT guangjuntian aversatilestrategyforsurfacefunctionalizationofhydrophobicnanoparticlebyboronicacidmodifiedpolymerizablediacetylenederivatives AT suyingxu aversatilestrategyforsurfacefunctionalizationofhydrophobicnanoparticlebyboronicacidmodifiedpolymerizablediacetylenederivatives AT leyuwang aversatilestrategyforsurfacefunctionalizationofhydrophobicnanoparticlebyboronicacidmodifiedpolymerizablediacetylenederivatives AT shiweigu versatilestrategyforsurfacefunctionalizationofhydrophobicnanoparticlebyboronicacidmodifiedpolymerizablediacetylenederivatives AT changguo versatilestrategyforsurfacefunctionalizationofhydrophobicnanoparticlebyboronicacidmodifiedpolymerizablediacetylenederivatives AT huiwang versatilestrategyforsurfacefunctionalizationofhydrophobicnanoparticlebyboronicacidmodifiedpolymerizablediacetylenederivatives AT guangjuntian versatilestrategyforsurfacefunctionalizationofhydrophobicnanoparticlebyboronicacidmodifiedpolymerizablediacetylenederivatives AT suyingxu versatilestrategyforsurfacefunctionalizationofhydrophobicnanoparticlebyboronicacidmodifiedpolymerizablediacetylenederivatives AT leyuwang versatilestrategyforsurfacefunctionalizationofhydrophobicnanoparticlebyboronicacidmodifiedpolymerizablediacetylenederivatives |