Japanese encephalitis virus infection in South-East Asia: An immuno-epidemiological twist
Background:Japanese encephalitis (JE) is one of the most important zoonotic diseases in a cosmopolitan manner. Japanese encephalitis virus (JEV) infection represents at least 70 % of emerging diseases caused by the mosquito-borne JEV. Nearly 20-30% of case fatality corroborated in JEV infections w...
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| Format: | Article |
| Language: | English |
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Zagazig University, Faculty of Medicine
2022-05-01
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| Series: | Microbes and Infectious Diseases |
| Subjects: | |
| Online Access: | https://mid.journals.ekb.eg/article_195676_aaaf4a9f123f06efec24ef09655186a0.pdf |
| _version_ | 1811229519100510208 |
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| author | Ferdaus Hossain Farzana Sumaiya Badruzzaman ATM Md Masudur Rahman |
| author_facet | Ferdaus Hossain Farzana Sumaiya Badruzzaman ATM Md Masudur Rahman |
| author_sort | Ferdaus Hossain |
| collection | DOAJ |
| description | Background:Japanese encephalitis (JE) is one of the most important zoonotic diseases in a cosmopolitan manner. Japanese encephalitis virus (JEV) infection represents at least 70 % of emerging diseases caused by the mosquito-borne JEV. Nearly 20-30% of case fatality corroborated in JEV infections with 30-50% neurologic and psychiatric disorders. A strong epidemic distribution is observed mainly in South-East Asia, demonstrating typical seasonal characteristics and occasional outbreaks. Depending on the genetic diversity, geographical distribution, and emerging natures of JEV, the disease surveillance, and immunization strategies are also varied. Uncontrolled population growth, haphazard agro-animal farming, and ecological imbalance steer the emergence and reemergence of JEV occurrences. Some murine models elucidate the immunological phenomena of JEV infections, the more detailed pathogenesis depending on the genetic variation is yet to be well defined. And the immune-epidemiological traits also address significant concerns regarding the effective vaccines and immunotherapeutics against JEV infections. Therefore, we summarized some critical notions on molecular epidemiology, immunogenicity, and genetic variance of JEV in South-East Asia. |
| first_indexed | 2024-04-12T10:15:53Z |
| format | Article |
| id | doaj.art-49e53930f80943718e4785fce1c1c57e |
| institution | Directory Open Access Journal |
| issn | 2682-4132 2682-4140 |
| language | English |
| last_indexed | 2024-04-12T10:15:53Z |
| publishDate | 2022-05-01 |
| publisher | Zagazig University, Faculty of Medicine |
| record_format | Article |
| series | Microbes and Infectious Diseases |
| spelling | doaj.art-49e53930f80943718e4785fce1c1c57e2022-12-22T03:37:12ZengZagazig University, Faculty of MedicineMicrobes and Infectious Diseases2682-41322682-41402022-05-013224124510.21608/mid.2021.93295.1188195676Japanese encephalitis virus infection in South-East Asia: An immuno-epidemiological twistFerdaus Hossain0Farzana Sumaiya1Badruzzaman ATM2Md Masudur Rahman3Faculty of Veterinary, Animal and Biomedical Sciences, Sylhet Agricultural University, BangladeshDepartment of Gynecology and Obstetrics, Women's Medical College, Sylhet, BangladeshNational Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, TaiwanFaculty of Veterinary, Animal and Biomedical Sciences, Sylhet Agricultural University, BangladeshBackground:Japanese encephalitis (JE) is one of the most important zoonotic diseases in a cosmopolitan manner. Japanese encephalitis virus (JEV) infection represents at least 70 % of emerging diseases caused by the mosquito-borne JEV. Nearly 20-30% of case fatality corroborated in JEV infections with 30-50% neurologic and psychiatric disorders. A strong epidemic distribution is observed mainly in South-East Asia, demonstrating typical seasonal characteristics and occasional outbreaks. Depending on the genetic diversity, geographical distribution, and emerging natures of JEV, the disease surveillance, and immunization strategies are also varied. Uncontrolled population growth, haphazard agro-animal farming, and ecological imbalance steer the emergence and reemergence of JEV occurrences. Some murine models elucidate the immunological phenomena of JEV infections, the more detailed pathogenesis depending on the genetic variation is yet to be well defined. And the immune-epidemiological traits also address significant concerns regarding the effective vaccines and immunotherapeutics against JEV infections. Therefore, we summarized some critical notions on molecular epidemiology, immunogenicity, and genetic variance of JEV in South-East Asia.https://mid.journals.ekb.eg/article_195676_aaaf4a9f123f06efec24ef09655186a0.pdfjapanese encephalitis virusimmunogenicitymolecular epidemiologysoutheast asia |
| spellingShingle | Ferdaus Hossain Farzana Sumaiya Badruzzaman ATM Md Masudur Rahman Japanese encephalitis virus infection in South-East Asia: An immuno-epidemiological twist Microbes and Infectious Diseases japanese encephalitis virus immunogenicity molecular epidemiology southeast asia |
| title | Japanese encephalitis virus infection in South-East Asia: An immuno-epidemiological twist |
| title_full | Japanese encephalitis virus infection in South-East Asia: An immuno-epidemiological twist |
| title_fullStr | Japanese encephalitis virus infection in South-East Asia: An immuno-epidemiological twist |
| title_full_unstemmed | Japanese encephalitis virus infection in South-East Asia: An immuno-epidemiological twist |
| title_short | Japanese encephalitis virus infection in South-East Asia: An immuno-epidemiological twist |
| title_sort | japanese encephalitis virus infection in south east asia an immuno epidemiological twist |
| topic | japanese encephalitis virus immunogenicity molecular epidemiology southeast asia |
| url | https://mid.journals.ekb.eg/article_195676_aaaf4a9f123f06efec24ef09655186a0.pdf |
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