Isolated Third, Fourth, and Sixth Cranial Nerve Palsies in the Turkish Population: Etiologic Factors and Clinical Course
Objective: To determine the etiologic factors and clinical profile of isolated third, fourth, and sixth nerve palsies in neuro-ophthalmology outpatient clinics of two different reference centers. Materials and Methods: Retrospective evaluation of medical records from the institutional database. Re...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2019-03-01
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| Series: | Türk Nöroloji Dergisi |
| Subjects: | |
| Online Access: | http://www.tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-29795 |
| _version_ | 1828016197772247040 |
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| author | Ayşe İlksen Çolpak Hale Batur Çağlayan |
| author_facet | Ayşe İlksen Çolpak Hale Batur Çağlayan |
| author_sort | Ayşe İlksen Çolpak |
| collection | DOAJ |
| description | Objective: To determine the etiologic factors and clinical profile of isolated third, fourth, and sixth nerve palsies in neuro-ophthalmology outpatient clinics of two different reference centers.
Materials and Methods: Retrospective evaluation of medical records from the institutional database.
Results: A total of 127 (78 male, 49 female) patients were analyzed. Forty-five (35.4%) patients had isolated third nerve palsy, 34 (26.8%) had isolated fourth nerve palsy, and 48 (37.8%) patients had isolated sixth nerve palsy. The mean ages were similar; 58.87±13.6, 56.32±16.1, and 54.9±14.4 years, respectively (p=0.4). Diplopia was the main symptom seen in all patients. Twenty-one patients had anisocoria (20 third, 1 fourth). Among patients with anisocoria, 3 patients had final diagnoses of vasculopathy, the rest were diagnosed as having acquired non travmatic palsy with different etiologies such as aneurysm, Tolosa-Hunt syndrome, and carotico-cavernous fistula. The most common etiology for all groups was vasculopathy. Three patients with isolated oculomotor nerve palsy were diagnosed as having Tolosa-Hunt sydnrome despite pupillary sparing. The mean recovery time was similar for all cranial nerve palsies.
Conclusion: Although, the most common etiology of third, fourth, and sixth nerve palsies is vasculopathy, neuroimaging studies are crucial to exclude potentially treatable and dangerous conditions. |
| first_indexed | 2024-04-10T10:29:47Z |
| format | Article |
| id | doaj.art-49ea1d4bbc9a44faa1d8b5b0c7450df3 |
| institution | Directory Open Access Journal |
| issn | 1309-2545 |
| language | English |
| last_indexed | 2024-04-10T10:29:47Z |
| publishDate | 2019-03-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Türk Nöroloji Dergisi |
| spelling | doaj.art-49ea1d4bbc9a44faa1d8b5b0c7450df32023-02-15T16:21:10ZengGalenos YayineviTürk Nöroloji Dergisi1309-25452019-03-01251323510.4274/tnd.galenos.2019.29795Isolated Third, Fourth, and Sixth Cranial Nerve Palsies in the Turkish Population: Etiologic Factors and Clinical CourseAyşe İlksen Çolpak0Hale Batur Çağlayan1Hacettepe University Faculty of Medicine, Department of Neurology, Ankara, TurkeyGazi University Faculty of Medicine, Department of Neurology, Ankara, TurkeyObjective: To determine the etiologic factors and clinical profile of isolated third, fourth, and sixth nerve palsies in neuro-ophthalmology outpatient clinics of two different reference centers. Materials and Methods: Retrospective evaluation of medical records from the institutional database. Results: A total of 127 (78 male, 49 female) patients were analyzed. Forty-five (35.4%) patients had isolated third nerve palsy, 34 (26.8%) had isolated fourth nerve palsy, and 48 (37.8%) patients had isolated sixth nerve palsy. The mean ages were similar; 58.87±13.6, 56.32±16.1, and 54.9±14.4 years, respectively (p=0.4). Diplopia was the main symptom seen in all patients. Twenty-one patients had anisocoria (20 third, 1 fourth). Among patients with anisocoria, 3 patients had final diagnoses of vasculopathy, the rest were diagnosed as having acquired non travmatic palsy with different etiologies such as aneurysm, Tolosa-Hunt syndrome, and carotico-cavernous fistula. The most common etiology for all groups was vasculopathy. Three patients with isolated oculomotor nerve palsy were diagnosed as having Tolosa-Hunt sydnrome despite pupillary sparing. The mean recovery time was similar for all cranial nerve palsies. Conclusion: Although, the most common etiology of third, fourth, and sixth nerve palsies is vasculopathy, neuroimaging studies are crucial to exclude potentially treatable and dangerous conditions.http://www.tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-29795Diplopiathird nerve palsyfourth nerve palsysixth nerve pals |
| spellingShingle | Ayşe İlksen Çolpak Hale Batur Çağlayan Isolated Third, Fourth, and Sixth Cranial Nerve Palsies in the Turkish Population: Etiologic Factors and Clinical Course Türk Nöroloji Dergisi Diplopia third nerve palsy fourth nerve palsy sixth nerve pals |
| title | Isolated Third, Fourth, and Sixth Cranial Nerve Palsies in the Turkish Population: Etiologic Factors and Clinical Course |
| title_full | Isolated Third, Fourth, and Sixth Cranial Nerve Palsies in the Turkish Population: Etiologic Factors and Clinical Course |
| title_fullStr | Isolated Third, Fourth, and Sixth Cranial Nerve Palsies in the Turkish Population: Etiologic Factors and Clinical Course |
| title_full_unstemmed | Isolated Third, Fourth, and Sixth Cranial Nerve Palsies in the Turkish Population: Etiologic Factors and Clinical Course |
| title_short | Isolated Third, Fourth, and Sixth Cranial Nerve Palsies in the Turkish Population: Etiologic Factors and Clinical Course |
| title_sort | isolated third fourth and sixth cranial nerve palsies in the turkish population etiologic factors and clinical course |
| topic | Diplopia third nerve palsy fourth nerve palsy sixth nerve pals |
| url | http://www.tjn.org.tr/jvi.aspx?pdir=tjn&plng=eng&un=TJN-29795 |
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