| Summary: | This paper aims to understand the bioaccumulation of pyraoxystrobin in fish. Using a flow-through bioconcentration method, the bioconcentration factor (<i>BCF</i>) and clearance rate of pyraoxystrobin in zebrafish were measured. The measured <i>BCF</i> values were then compared to those estimated from three commonly used predication models. At the exposure concentrations of 0.1 μg/L and 1.0 μg/L, the maximum <i>BCF</i> values for pyraoxystrobin in fish were 820.8 and 265.9, and the absorption rate constants (<i>K</i><sub>1</sub>) were 391.0 d<sup>−1</sup> and 153.2 d<sup>−1</sup>, respectively. The maximum enrichment occurred at 12 d of exposure. At the two test concentrations, the clearance rate constant (<i>K</i><sub>2</sub>) in zebrafish was 0.5795 and 0.4721, and the half-life (<i>t</i><sub>1/2</sub>) was 3.84 d and 3.33 d, respectively. The measured BCF values were close to those estimated from bioconcentration predication models.
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