Post-void residual urine ratio: A novel clinical approach to the post-void residual urine in the assessment of males with lower urinary tract symptoms
Purpose: To assess the correlation between post-void residual urine ratio (PVR-R) and pathological bladder emptying diagnosed by pressure-flow studies (PFS) in males with lower urinary tract symptoms (LUTS). Materials and Methods: PVR-R and PVR urine were evaluated in 410 males underwent PFS for LU...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Korean Urological Association
2021-07-01
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| Series: | Investigative and Clinical Urology |
| Subjects: | |
| Online Access: | https://icurology.org/pdf/10.4111/icu.20200560 |
| _version_ | 1831751633879433216 |
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| author | Emanuele Rubilotta Matteo Balzarro Nicolò Trabacchin Rita Righetti Antonio D'Amico Jerry G. Blaivas Alessandro Antonelli |
| author_facet | Emanuele Rubilotta Matteo Balzarro Nicolò Trabacchin Rita Righetti Antonio D'Amico Jerry G. Blaivas Alessandro Antonelli |
| author_sort | Emanuele Rubilotta |
| collection | DOAJ |
| description | Purpose: To assess the correlation between post-void residual urine ratio (PVR-R) and pathological bladder emptying diagnosed by pressure-flow studies (PFS) in males with lower urinary tract symptoms (LUTS).
Materials and Methods: PVR-R and PVR urine were evaluated in 410 males underwent PFS for LUTS. PVR-R was the percentage of PVR to bladder volume (voided volume+PVR). Schafer and International Continence Society (ICS) nomograms, Bladder Contractility Index (BCI) were used to diagnose bladder outlet obstruction (BOO) and detrusor underactivity (DUA). We subdivided the cohort in 4 groups: Group I, BOO+/DUA+; Group II, BOO-/DUA+; Group III, BOO+/DUA−; Group IV, BOO−/DUA− (control group). We subdivided the 4 groups according to PVR-R strata: (1) 0%–20%; (2) 21%–40%; (3) 41%–60%; (4) 61%–80%; (5) 81%–100%.
Results: Group I had a greater median PVR-R (50%) with a >40% in 61.4% of the cohort. Median PVR-R was 16.6% in Group II, 24% in Group III, and 0% in the control Group. According to ICS nomograms and BCI, median PVR-R and PVR were significantly higher (p<0.001) in obstructed and underactive males. PVR-R threshold of 20% allowed to recognize males with voiding disorders with high sensibility, specificity, PPV, and NPV. A PVR-R cut-off of 40% identified males with associated BOO and DUA and more severe voiding dysfunction.
Conclusions: A higher PVR-R is related to a more severe pathological bladder emptying, and to the association of BOO and DUA. PVR-R may have a clinical role in first assessment of males with LUTS and severe voiding dysfunction. |
| first_indexed | 2024-12-21T22:48:10Z |
| format | Article |
| id | doaj.art-49f03710cd86476fa02d9b81706b37e8 |
| institution | Directory Open Access Journal |
| issn | 2466-0493 2466-054X |
| language | English |
| last_indexed | 2024-12-21T22:48:10Z |
| publishDate | 2021-07-01 |
| publisher | Korean Urological Association |
| record_format | Article |
| series | Investigative and Clinical Urology |
| spelling | doaj.art-49f03710cd86476fa02d9b81706b37e82022-12-21T18:47:38ZengKorean Urological AssociationInvestigative and Clinical Urology2466-04932466-054X2021-07-0162447047610.4111/icu.20200560Post-void residual urine ratio: A novel clinical approach to the post-void residual urine in the assessment of males with lower urinary tract symptomsEmanuele Rubilotta 0https://orcid.org/0000-0002-3490-947XMatteo Balzarro 1https://orcid.org/0000-0003-1019-565XNicolò Trabacchin2https://orcid.org/0000-0003-3689-1469Rita Righetti 3https://orcid.org/0000-0003-3139-3794Antonio D'Amico4https://orcid.org/0000-0002-8054-749XJerry G. Blaivas 5https://orcid.org/0000-0003-0410-8476Alessandro Antonelli 6https://orcid.org/0000-0002-9557-3586Department of Urology, AOUI Verona, Verona, Italy.Department of Urology, AOUI Verona, Verona, Italy.Department of Urology, AOUI Verona, Verona, Italy.Department of Urology, Mater Salutis Hospital AULSS 9 Scaligera, Legnago, Italy.Department of Urology, AOUI Verona, Verona, Italy.Department of Urology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.Department of Urology, AOUI Verona, Verona, Italy.Purpose: To assess the correlation between post-void residual urine ratio (PVR-R) and pathological bladder emptying diagnosed by pressure-flow studies (PFS) in males with lower urinary tract symptoms (LUTS). Materials and Methods: PVR-R and PVR urine were evaluated in 410 males underwent PFS for LUTS. PVR-R was the percentage of PVR to bladder volume (voided volume+PVR). Schafer and International Continence Society (ICS) nomograms, Bladder Contractility Index (BCI) were used to diagnose bladder outlet obstruction (BOO) and detrusor underactivity (DUA). We subdivided the cohort in 4 groups: Group I, BOO+/DUA+; Group II, BOO-/DUA+; Group III, BOO+/DUA−; Group IV, BOO−/DUA− (control group). We subdivided the 4 groups according to PVR-R strata: (1) 0%–20%; (2) 21%–40%; (3) 41%–60%; (4) 61%–80%; (5) 81%–100%. Results: Group I had a greater median PVR-R (50%) with a >40% in 61.4% of the cohort. Median PVR-R was 16.6% in Group II, 24% in Group III, and 0% in the control Group. According to ICS nomograms and BCI, median PVR-R and PVR were significantly higher (p<0.001) in obstructed and underactive males. PVR-R threshold of 20% allowed to recognize males with voiding disorders with high sensibility, specificity, PPV, and NPV. A PVR-R cut-off of 40% identified males with associated BOO and DUA and more severe voiding dysfunction. Conclusions: A higher PVR-R is related to a more severe pathological bladder emptying, and to the association of BOO and DUA. PVR-R may have a clinical role in first assessment of males with LUTS and severe voiding dysfunction.https://icurology.org/pdf/10.4111/icu.20200560bladder outlet obstructiondetrusor underactivitylower urinary tract symptomsmalesurodynamics |
| spellingShingle | Emanuele Rubilotta Matteo Balzarro Nicolò Trabacchin Rita Righetti Antonio D'Amico Jerry G. Blaivas Alessandro Antonelli Post-void residual urine ratio: A novel clinical approach to the post-void residual urine in the assessment of males with lower urinary tract symptoms Investigative and Clinical Urology bladder outlet obstruction detrusor underactivity lower urinary tract symptoms males urodynamics |
| title | Post-void residual urine ratio: A novel clinical approach to the post-void residual urine in the assessment of males with lower urinary tract symptoms |
| title_full | Post-void residual urine ratio: A novel clinical approach to the post-void residual urine in the assessment of males with lower urinary tract symptoms |
| title_fullStr | Post-void residual urine ratio: A novel clinical approach to the post-void residual urine in the assessment of males with lower urinary tract symptoms |
| title_full_unstemmed | Post-void residual urine ratio: A novel clinical approach to the post-void residual urine in the assessment of males with lower urinary tract symptoms |
| title_short | Post-void residual urine ratio: A novel clinical approach to the post-void residual urine in the assessment of males with lower urinary tract symptoms |
| title_sort | post void residual urine ratio a novel clinical approach to the post void residual urine in the assessment of males with lower urinary tract symptoms |
| topic | bladder outlet obstruction detrusor underactivity lower urinary tract symptoms males urodynamics |
| url | https://icurology.org/pdf/10.4111/icu.20200560 |
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