A Promising Electrochemical Platform for Dopamine and Uric Acid Detection Based on a Polyaniline/Iron Oxide-Tin Oxide/Reduced Graphene Oxide Ternary Composite
A ternary polyaniline/Fe<sub>2</sub>O<sub>3</sub>-SnO<sub>2</sub>/reduced graphene oxide (PFSG) nanocomposite was prepared using a simple two-step hydrothermal treatment. The composite was applied as a glassy carbon electrode modifier (GCE) to enhance dopamine (DA...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-12-01
|
| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/25/24/5869 |
| _version_ | 1797544948577337344 |
|---|---|
| author | Daria Minta Adam Moyseowicz Stanisław Gryglewicz Grażyna Gryglewicz |
| author_facet | Daria Minta Adam Moyseowicz Stanisław Gryglewicz Grażyna Gryglewicz |
| author_sort | Daria Minta |
| collection | DOAJ |
| description | A ternary polyaniline/Fe<sub>2</sub>O<sub>3</sub>-SnO<sub>2</sub>/reduced graphene oxide (PFSG) nanocomposite was prepared using a simple two-step hydrothermal treatment. The composite was applied as a glassy carbon electrode modifier (GCE) to enhance dopamine (DA) and uric acid (UA) detection. The ternary PFSG composite was compared with its binary precursor Fe<sub>2</sub>O<sub>3</sub>-SnO<sub>2</sub>/reduced graphene oxide (FSG). The influence of the modified GCE electrodes on their performance as a sensing platform was determined. GCE/PFSG showed better sensing parameters than GCE/FSG due to the introduction of polyaniline (PANI), increasing the electrocatalytic properties of the electrode towards the detected analytes. GCE/PFSG enabled the detection of low concentrations of DA (0.076 µM) and UA (1.6 µM). The peak potential separation between DA and UA was very good (180 mV). Moreover, the DA oxidation peak was unaffected even if the concentration of UA was ten times higher. The fabricated sensor showed excellent performance in the simultaneous detection with DA and UA limits of detection: LOD<sub>DA</sub> = 0.15 µM and LOD<sub>UA</sub> = 6.4 µM, and outstanding long-term stability towards DA and UA, holding 100% and 90% of their initial signals respectively, after one month of use. |
| first_indexed | 2024-03-10T14:07:41Z |
| format | Article |
| id | doaj.art-49f05130a9b344a0bce7a0cd2519a04d |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T14:07:41Z |
| publishDate | 2020-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-49f05130a9b344a0bce7a0cd2519a04d2023-11-21T00:27:31ZengMDPI AGMolecules1420-30492020-12-012524586910.3390/molecules25245869A Promising Electrochemical Platform for Dopamine and Uric Acid Detection Based on a Polyaniline/Iron Oxide-Tin Oxide/Reduced Graphene Oxide Ternary CompositeDaria Minta0Adam Moyseowicz1Stanisław Gryglewicz2Grażyna Gryglewicz3Department of Process Engineering and Technology of Polymer and Carbon Materials, Faculty of Chemistry, Wrocław University of Science and Technology, Gdańska 7/9, 50-344 Wrocław, PolandDepartment of Process Engineering and Technology of Polymer and Carbon Materials, Faculty of Chemistry, Wrocław University of Science and Technology, Gdańska 7/9, 50-344 Wrocław, PolandDepartment of Engineering and Technology of Chemical Processes, Faculty of Chemistry, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 42, 50-344 Wrocław, PolandDepartment of Process Engineering and Technology of Polymer and Carbon Materials, Faculty of Chemistry, Wrocław University of Science and Technology, Gdańska 7/9, 50-344 Wrocław, PolandA ternary polyaniline/Fe<sub>2</sub>O<sub>3</sub>-SnO<sub>2</sub>/reduced graphene oxide (PFSG) nanocomposite was prepared using a simple two-step hydrothermal treatment. The composite was applied as a glassy carbon electrode modifier (GCE) to enhance dopamine (DA) and uric acid (UA) detection. The ternary PFSG composite was compared with its binary precursor Fe<sub>2</sub>O<sub>3</sub>-SnO<sub>2</sub>/reduced graphene oxide (FSG). The influence of the modified GCE electrodes on their performance as a sensing platform was determined. GCE/PFSG showed better sensing parameters than GCE/FSG due to the introduction of polyaniline (PANI), increasing the electrocatalytic properties of the electrode towards the detected analytes. GCE/PFSG enabled the detection of low concentrations of DA (0.076 µM) and UA (1.6 µM). The peak potential separation between DA and UA was very good (180 mV). Moreover, the DA oxidation peak was unaffected even if the concentration of UA was ten times higher. The fabricated sensor showed excellent performance in the simultaneous detection with DA and UA limits of detection: LOD<sub>DA</sub> = 0.15 µM and LOD<sub>UA</sub> = 6.4 µM, and outstanding long-term stability towards DA and UA, holding 100% and 90% of their initial signals respectively, after one month of use.https://www.mdpi.com/1420-3049/25/24/5869electrochemical sensordopamine and uric acid detectionternary nanocompositehydrothermal treatment |
| spellingShingle | Daria Minta Adam Moyseowicz Stanisław Gryglewicz Grażyna Gryglewicz A Promising Electrochemical Platform for Dopamine and Uric Acid Detection Based on a Polyaniline/Iron Oxide-Tin Oxide/Reduced Graphene Oxide Ternary Composite Molecules electrochemical sensor dopamine and uric acid detection ternary nanocomposite hydrothermal treatment |
| title | A Promising Electrochemical Platform for Dopamine and Uric Acid Detection Based on a Polyaniline/Iron Oxide-Tin Oxide/Reduced Graphene Oxide Ternary Composite |
| title_full | A Promising Electrochemical Platform for Dopamine and Uric Acid Detection Based on a Polyaniline/Iron Oxide-Tin Oxide/Reduced Graphene Oxide Ternary Composite |
| title_fullStr | A Promising Electrochemical Platform for Dopamine and Uric Acid Detection Based on a Polyaniline/Iron Oxide-Tin Oxide/Reduced Graphene Oxide Ternary Composite |
| title_full_unstemmed | A Promising Electrochemical Platform for Dopamine and Uric Acid Detection Based on a Polyaniline/Iron Oxide-Tin Oxide/Reduced Graphene Oxide Ternary Composite |
| title_short | A Promising Electrochemical Platform for Dopamine and Uric Acid Detection Based on a Polyaniline/Iron Oxide-Tin Oxide/Reduced Graphene Oxide Ternary Composite |
| title_sort | promising electrochemical platform for dopamine and uric acid detection based on a polyaniline iron oxide tin oxide reduced graphene oxide ternary composite |
| topic | electrochemical sensor dopamine and uric acid detection ternary nanocomposite hydrothermal treatment |
| url | https://www.mdpi.com/1420-3049/25/24/5869 |
| work_keys_str_mv | AT dariaminta apromisingelectrochemicalplatformfordopamineanduricaciddetectionbasedonapolyanilineironoxidetinoxidereducedgrapheneoxideternarycomposite AT adammoyseowicz apromisingelectrochemicalplatformfordopamineanduricaciddetectionbasedonapolyanilineironoxidetinoxidereducedgrapheneoxideternarycomposite AT stanisławgryglewicz apromisingelectrochemicalplatformfordopamineanduricaciddetectionbasedonapolyanilineironoxidetinoxidereducedgrapheneoxideternarycomposite AT grazynagryglewicz apromisingelectrochemicalplatformfordopamineanduricaciddetectionbasedonapolyanilineironoxidetinoxidereducedgrapheneoxideternarycomposite AT dariaminta promisingelectrochemicalplatformfordopamineanduricaciddetectionbasedonapolyanilineironoxidetinoxidereducedgrapheneoxideternarycomposite AT adammoyseowicz promisingelectrochemicalplatformfordopamineanduricaciddetectionbasedonapolyanilineironoxidetinoxidereducedgrapheneoxideternarycomposite AT stanisławgryglewicz promisingelectrochemicalplatformfordopamineanduricaciddetectionbasedonapolyanilineironoxidetinoxidereducedgrapheneoxideternarycomposite AT grazynagryglewicz promisingelectrochemicalplatformfordopamineanduricaciddetectionbasedonapolyanilineironoxidetinoxidereducedgrapheneoxideternarycomposite |