Anatomical substrate and scalp EEG markers are correlated in subjects with cognitive impairment and Alzheimer’s disease
Dementia is a syndromic diagnosis, encompassing various stage of severity and different anatomo-physiological substrates. The hippocampus is one of the first and most affected brain regions affected by both Alzheimer’s disease (AD) and mild cognitive impairment (MCI). Morevoer, cronic cerebrovascula...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2011-01-01
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| Series: | Frontiers in Psychiatry |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fpsyt.2010.00152/full |
| _version_ | 1819230694991200256 |
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| author | davide v Moretti giovanni b Frisoni giuliano Binetti orazio Zanetti |
| author_facet | davide v Moretti giovanni b Frisoni giuliano Binetti orazio Zanetti |
| author_sort | davide v Moretti |
| collection | DOAJ |
| description | Dementia is a syndromic diagnosis, encompassing various stage of severity and different anatomo-physiological substrates. The hippocampus is one of the first and most affected brain regions affected by both Alzheimer’s disease (AD) and mild cognitive impairment (MCI). Morevoer, cronic cerebrovascular disease (CVD) is one of the major risk factor for developing dementia. Recent studies have demonstrated different relationship between the anatomical substrate and scalp electroencephalography (EEG) markers. Indeed, modifications of EEG rhythmicity is not proportional to the hippocampal atrophy, whereas changes in EEG activity are directly proportional to the load of subcortical CVD.Quantitative EEG have been demonstrated a reliable tool in identifying specific patterns in dementia research (Coburn et al., 2006; John and Prichep, 2006). The computation of the spectral power and the analysis of the functional coupling of brain areas, through linear coherence, are two of the most known processing methods in EEG research. Two specific EEG markers, theta/gamma and alpha3/alpha2 frequency ratio have been reliable associated to the atrophy of amygdalo-hippocampal complex. Moreover, theta/gamma ratio has been related to MCI conversion i |
| first_indexed | 2024-12-23T11:33:09Z |
| format | Article |
| id | doaj.art-49f46853a7fb451aa254a29671e202f7 |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-12-23T11:33:09Z |
| publishDate | 2011-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-49f46853a7fb451aa254a29671e202f72022-12-21T17:48:43ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402011-01-01110.3389/fpsyt.2010.001522068Anatomical substrate and scalp EEG markers are correlated in subjects with cognitive impairment and Alzheimer’s diseasedavide v Moretti0giovanni b Frisoni1giuliano Binetti2orazio Zanetti3S GIOVANNI DI DIO FATEBENEFRATELLI IRCCSS GIOVANNI DI DIO FATEBENEFRATELLI IRCCSS GIOVANNI DI DIO FATEBENEFRATELLI IRCCSS GIOVANNI DI DIO FATEBENEFRATELLI IRCCSDementia is a syndromic diagnosis, encompassing various stage of severity and different anatomo-physiological substrates. The hippocampus is one of the first and most affected brain regions affected by both Alzheimer’s disease (AD) and mild cognitive impairment (MCI). Morevoer, cronic cerebrovascular disease (CVD) is one of the major risk factor for developing dementia. Recent studies have demonstrated different relationship between the anatomical substrate and scalp electroencephalography (EEG) markers. Indeed, modifications of EEG rhythmicity is not proportional to the hippocampal atrophy, whereas changes in EEG activity are directly proportional to the load of subcortical CVD.Quantitative EEG have been demonstrated a reliable tool in identifying specific patterns in dementia research (Coburn et al., 2006; John and Prichep, 2006). The computation of the spectral power and the analysis of the functional coupling of brain areas, through linear coherence, are two of the most known processing methods in EEG research. Two specific EEG markers, theta/gamma and alpha3/alpha2 frequency ratio have been reliable associated to the atrophy of amygdalo-hippocampal complex. Moreover, theta/gamma ratio has been related to MCI conversion ihttp://journal.frontiersin.org/Journal/10.3389/fpsyt.2010.00152/fullAlpha RhythmMild Cognitive ImpairmentTheta RhythmAlzheimer's diseaseEEG markersgamma rhythm |
| spellingShingle | davide v Moretti giovanni b Frisoni giuliano Binetti orazio Zanetti Anatomical substrate and scalp EEG markers are correlated in subjects with cognitive impairment and Alzheimer’s disease Frontiers in Psychiatry Alpha Rhythm Mild Cognitive Impairment Theta Rhythm Alzheimer's disease EEG markers gamma rhythm |
| title | Anatomical substrate and scalp EEG markers are correlated in subjects with cognitive impairment and Alzheimer’s disease |
| title_full | Anatomical substrate and scalp EEG markers are correlated in subjects with cognitive impairment and Alzheimer’s disease |
| title_fullStr | Anatomical substrate and scalp EEG markers are correlated in subjects with cognitive impairment and Alzheimer’s disease |
| title_full_unstemmed | Anatomical substrate and scalp EEG markers are correlated in subjects with cognitive impairment and Alzheimer’s disease |
| title_short | Anatomical substrate and scalp EEG markers are correlated in subjects with cognitive impairment and Alzheimer’s disease |
| title_sort | anatomical substrate and scalp eeg markers are correlated in subjects with cognitive impairment and alzheimer s disease |
| topic | Alpha Rhythm Mild Cognitive Impairment Theta Rhythm Alzheimer's disease EEG markers gamma rhythm |
| url | http://journal.frontiersin.org/Journal/10.3389/fpsyt.2010.00152/full |
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