A Miniaturized Electrothermal-MEMS-Based Optical Coherence Tomography (OCT) Handheld Microscope
Swept-source optical coherence tomography (SS-OCT), benefiting from its high sensitivity, relatively large penetration depth, and non-contact and non-invasive imaging capability, is ideal for human skin imaging. However, limited by the size and performance of the reported optical galvanometer scanne...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-12-01
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| Series: | Photonics |
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| Online Access: | https://www.mdpi.com/2304-6732/11/1/17 |
| _version_ | 1797342716088025088 |
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| author | Qian Chen Hui Zhao Tingxiang Qi Hua Wang Huikai Xie |
| author_facet | Qian Chen Hui Zhao Tingxiang Qi Hua Wang Huikai Xie |
| author_sort | Qian Chen |
| collection | DOAJ |
| description | Swept-source optical coherence tomography (SS-OCT), benefiting from its high sensitivity, relatively large penetration depth, and non-contact and non-invasive imaging capability, is ideal for human skin imaging. However, limited by the size and performance of the reported optical galvanometer scanners, existing portable/handheld OCT probes are still bulky, which makes continuously handheld imaging difficult. Here, we reported a miniaturized electrothermal-MEMS-based SS-OCT microscope that only weighs about 25 g and has a cylinder with a diameter of 15 mm and a length of 40 mm. This MEMS-based handheld imaging probe can achieve a lateral resolution of 25 μm, a 3D imaging time of 5 s, a penetration depth of up to 3.3 mm, and an effective imaging field of view (FOV) of 3 × 3 mm<sup>2</sup>. We have carried out both calibration plate and biological tissue imaging experiments to test the imaging performance of this microscope. OCT imaging of leaves, dragonfly, and human skin has been successfully obtained, showing the imaging performance and potential applications of this probe on human skin in the future. |
| first_indexed | 2024-03-08T10:37:19Z |
| format | Article |
| id | doaj.art-49f494f96f9446bab4650041a9167617 |
| institution | Directory Open Access Journal |
| issn | 2304-6732 |
| language | English |
| last_indexed | 2024-03-08T10:37:19Z |
| publishDate | 2023-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Photonics |
| spelling | doaj.art-49f494f96f9446bab4650041a91676172024-01-26T18:09:25ZengMDPI AGPhotonics2304-67322023-12-011111710.3390/photonics11010017A Miniaturized Electrothermal-MEMS-Based Optical Coherence Tomography (OCT) Handheld MicroscopeQian Chen0Hui Zhao1Tingxiang Qi2Hua Wang3Huikai Xie4School of Integrated Circuits and Electronics, Beijing Institute of Technology, Beijing 100081, ChinaSchool of Integrated Circuits and Electronics, Beijing Institute of Technology, Beijing 100081, ChinaBIT Chongqing Institute of Microelectronics and Microsystems, Chongqing 400000, ChinaSchool of Integrated Circuits and Electronics, Beijing Institute of Technology, Beijing 100081, ChinaSchool of Integrated Circuits and Electronics, Beijing Institute of Technology, Beijing 100081, ChinaSwept-source optical coherence tomography (SS-OCT), benefiting from its high sensitivity, relatively large penetration depth, and non-contact and non-invasive imaging capability, is ideal for human skin imaging. However, limited by the size and performance of the reported optical galvanometer scanners, existing portable/handheld OCT probes are still bulky, which makes continuously handheld imaging difficult. Here, we reported a miniaturized electrothermal-MEMS-based SS-OCT microscope that only weighs about 25 g and has a cylinder with a diameter of 15 mm and a length of 40 mm. This MEMS-based handheld imaging probe can achieve a lateral resolution of 25 μm, a 3D imaging time of 5 s, a penetration depth of up to 3.3 mm, and an effective imaging field of view (FOV) of 3 × 3 mm<sup>2</sup>. We have carried out both calibration plate and biological tissue imaging experiments to test the imaging performance of this microscope. OCT imaging of leaves, dragonfly, and human skin has been successfully obtained, showing the imaging performance and potential applications of this probe on human skin in the future.https://www.mdpi.com/2304-6732/11/1/17electrothermal MEMSSS-OCThandheldhuman skin |
| spellingShingle | Qian Chen Hui Zhao Tingxiang Qi Hua Wang Huikai Xie A Miniaturized Electrothermal-MEMS-Based Optical Coherence Tomography (OCT) Handheld Microscope Photonics electrothermal MEMS SS-OCT handheld human skin |
| title | A Miniaturized Electrothermal-MEMS-Based Optical Coherence Tomography (OCT) Handheld Microscope |
| title_full | A Miniaturized Electrothermal-MEMS-Based Optical Coherence Tomography (OCT) Handheld Microscope |
| title_fullStr | A Miniaturized Electrothermal-MEMS-Based Optical Coherence Tomography (OCT) Handheld Microscope |
| title_full_unstemmed | A Miniaturized Electrothermal-MEMS-Based Optical Coherence Tomography (OCT) Handheld Microscope |
| title_short | A Miniaturized Electrothermal-MEMS-Based Optical Coherence Tomography (OCT) Handheld Microscope |
| title_sort | miniaturized electrothermal mems based optical coherence tomography oct handheld microscope |
| topic | electrothermal MEMS SS-OCT handheld human skin |
| url | https://www.mdpi.com/2304-6732/11/1/17 |
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