Comprehensive and definitive structural identities of Pneumocystis carinii sterols

Comprehensive and definitive structural identities of Pneumocystis carinii sterols

Pneumocystis causes a type of pneumonia in immunodeficient mammals, such as AIDS patients. Mammals cannot alkylate the C-24 position of the sterol side chain, nor can they desaturate C-22. Thus, the reactions leading to these sterol modifications are particularly attractive targets for the developme...

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Bibliographic Details
Main Authors:	José-Luis Giner, Hui Zhao, David H. Beach, Edward J. Parish, Koka Jayasimhulu, Edna S. Kaneshiro
Format:	Article
Language:	English
Published:	Elsevier 2002-07-01
Series:	Journal of Lipid Research
Subjects:	AIDS 24-alkylsterols drug targets gas-liquid chromatography mass spectrometry opportunistic infections
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520314747

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