Enhanced functional detection of synaptic calcium-permeable AMPA receptors using intracellular NASPM

Enhanced functional detection of synaptic calcium-permeable AMPA receptors using intracellular NASPM

Calcium-permeable AMPA-type glutamate receptors (CP-AMPARs) contribute to many forms of synaptic plasticity and pathology. They can be distinguished from GluA2-containing calcium-impermeable AMPARs by the inward rectification of their currents, which reflects voltage-dependent channel block by intra...

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Bibliographic Details
Main Authors: Ian Coombs, Cécile Bats, Craig A Sexton, Dorota Studniarczyk, Stuart G Cull-Candy, Mark Farrant
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-04-01
Series:eLife
Subjects:
AMPA-type glutamate receptor
excitatory postsynaptic current
TARP
spermine
NASPM
rectification
Online Access:https://elifesciences.org/articles/66765

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