The Effect of a Fast-Releasing Hydrogen Sulfide Donor on Vascularization of Subcutaneous Scaffolds in Immunocompetent and Immunocompromised Mice

The Effect of a Fast-Releasing Hydrogen Sulfide Donor on Vascularization of Subcutaneous Scaffolds in Immunocompetent and Immunocompromised Mice

Islet transplantation into subcutaneous polymer scaffolds has shown to successfully induce normoglycemia in type 1 diabetes models. Vascularization of these scaffolds is imperative for optimal control of glucose levels. We studied the effect of the vascular stimulator hydrogen sulfide (H<sub>2...

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Bibliographic Details
Main Authors: Alexandra M. Smink, Avid Najdahmadi, Michael Alexander, Shiri Li, Samuel Rodriquez, Harry van Goor, Jan-Luuk Hillebrands, Elliot Botvinick, Jonathan R. T. Lakey, Paul de Vos
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Biomolecules
Subjects:
immune system
vascularization
hydrogen sulfide
subcutaneous scaffolds
Online Access:https://www.mdpi.com/2218-273X/10/5/722

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