Polymorphisms in melatonin synthesis pathways: possible influences on depression

Polymorphisms in melatonin synthesis pathways: possible influences on depression

<p>Abstract</p> <p>Background</p> <p>It has been reported that rs4446909, a single nucleotide polymorphism (SNP) in the promoter of acetylserotonin methyltransferase (<it>ASMT</it>), influences the expression of the ASMT enzyme. The common G allele is associ...

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Bibliographic Details
Main Authors: McCarthy Michael J, Murray Sarah S, Tranah Greg J, Nievergelt Caroline M, Kripke Daniel F, Rex Katharine M, Parimi Neeta, Kelsoe John R
Format: Article
Language:English
Published: Ubiquity Press 2011-08-01
Series:Journal of Circadian Rhythms
Subjects:
ASMT
N-acetylserotonin
AANAT
melatonin
serotonin
depression
bipolar disorder
lithium
Online Access:http://www.jcircadianrhythms.com/content/9/1/8

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