Hematogenous dissemination of Candida dubliniensis causing spondylodiscitis and spinal abscess in a HIV-1 and HCV-coinfected patient

We report a case of spondylodiscitis and spinal abscess following haematogenous dissemination of the emerging yeast Candida dubliniensis in a human immunodeficiency virus-1 (HIV-1) and hepatitis C virus (HCV)-coinfected patient. Although C. dubliniensis is considered less virulent compared to its cl...

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Main Authors: Helmut J.F. Salzer, Thierry Rolling, Eva-Maria Klupp, Stefan Schmiedel
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Medical Mycology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211753915000068
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author Helmut J.F. Salzer
Thierry Rolling
Eva-Maria Klupp
Stefan Schmiedel
author_facet Helmut J.F. Salzer
Thierry Rolling
Eva-Maria Klupp
Stefan Schmiedel
author_sort Helmut J.F. Salzer
collection DOAJ
description We report a case of spondylodiscitis and spinal abscess following haematogenous dissemination of the emerging yeast Candida dubliniensis in a human immunodeficiency virus-1 (HIV-1) and hepatitis C virus (HCV)-coinfected patient. Although C. dubliniensis is considered less virulent compared to its closest known relative Candida albicans, reports of severe fungal infections are increasing. This case indicates that the pathogenicity of C. dubliniensis may be higher than previously believed. Therefore fungal infections caused by this dimorph fungus should be kept in mind in immunocompromised patients with spondylodiscitis and spinal abscess.
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spelling doaj.art-4a02c96f43bb418d96d7d0f228d98af42022-12-22T00:00:08ZengElsevierMedical Mycology Case Reports2211-75392015-06-018C172010.1016/j.mmcr.2015.02.001Hematogenous dissemination of Candida dubliniensis causing spondylodiscitis and spinal abscess in a HIV-1 and HCV-coinfected patientHelmut J.F. Salzer0Thierry Rolling1Eva-Maria Klupp2Stefan Schmiedel3Department of Internal Medicine I, University Medical Centre Hamburg-Eppendorf, Hamburg, GermanyDepartment of Internal Medicine I, University Medical Centre Hamburg-Eppendorf, Hamburg, GermanyInstitute of Medical Microbiology, Virology and Hygiene, University Medical Centre Hamburg-Eppendorf, Hamburg, GermanyDepartment of Internal Medicine I, University Medical Centre Hamburg-Eppendorf, Hamburg, GermanyWe report a case of spondylodiscitis and spinal abscess following haematogenous dissemination of the emerging yeast Candida dubliniensis in a human immunodeficiency virus-1 (HIV-1) and hepatitis C virus (HCV)-coinfected patient. Although C. dubliniensis is considered less virulent compared to its closest known relative Candida albicans, reports of severe fungal infections are increasing. This case indicates that the pathogenicity of C. dubliniensis may be higher than previously believed. Therefore fungal infections caused by this dimorph fungus should be kept in mind in immunocompromised patients with spondylodiscitis and spinal abscess.http://www.sciencedirect.com/science/article/pii/S2211753915000068Candida dubliniensisSpondylodiscitisSpinal abscessHuman immunodeficiency virus-1Hepatitis C virus
spellingShingle Helmut J.F. Salzer
Thierry Rolling
Eva-Maria Klupp
Stefan Schmiedel
Hematogenous dissemination of Candida dubliniensis causing spondylodiscitis and spinal abscess in a HIV-1 and HCV-coinfected patient
Medical Mycology Case Reports
Candida dubliniensis
Spondylodiscitis
Spinal abscess
Human immunodeficiency virus-1
Hepatitis C virus
title Hematogenous dissemination of Candida dubliniensis causing spondylodiscitis and spinal abscess in a HIV-1 and HCV-coinfected patient
title_full Hematogenous dissemination of Candida dubliniensis causing spondylodiscitis and spinal abscess in a HIV-1 and HCV-coinfected patient
title_fullStr Hematogenous dissemination of Candida dubliniensis causing spondylodiscitis and spinal abscess in a HIV-1 and HCV-coinfected patient
title_full_unstemmed Hematogenous dissemination of Candida dubliniensis causing spondylodiscitis and spinal abscess in a HIV-1 and HCV-coinfected patient
title_short Hematogenous dissemination of Candida dubliniensis causing spondylodiscitis and spinal abscess in a HIV-1 and HCV-coinfected patient
title_sort hematogenous dissemination of candida dubliniensis causing spondylodiscitis and spinal abscess in a hiv 1 and hcv coinfected patient
topic Candida dubliniensis
Spondylodiscitis
Spinal abscess
Human immunodeficiency virus-1
Hepatitis C virus
url http://www.sciencedirect.com/science/article/pii/S2211753915000068
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