Soluble fractalkine in the plasma of fibromyalgia patients
Fibromyalgia is a form of non-articular rheumatism in which inflammatory cytokines seem to be involved. However, there is still no analytical specific diagnostic criterion for this disease. The aim was to examine a possible role of fractalkine as a biomarker in fibromyalgia. Plasma levels of soluble...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Academia Brasileira de Ciências
2014-12-01
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| Series: | Anais da Academia Brasileira de Ciências |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652014000401915&lng=en&tlng=en |
| _version_ | 1818997694177214464 |
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| author | JUAN J. GARCIA EDUARDO ORTEGA |
| author_facet | JUAN J. GARCIA EDUARDO ORTEGA |
| author_sort | JUAN J. GARCIA |
| collection | DOAJ |
| description | Fibromyalgia is a form of non-articular rheumatism in which inflammatory cytokines seem to be involved. However, there is still no analytical specific diagnostic criterion for this disease. The aim was to examine a possible role of fractalkine as a biomarker in fibromyalgia. Plasma levels of soluble fractalkine were compared between women diagnosed with fibromyalgia (n=17) and healthy women (n=10) as controls. Fractalkine released by monocytes was also evaluated. Fibromyalgia patients showed lower plasma fractalkine than healthy women. Since most inflammatory pathologies show elevated plasma levels of soluble fractalkine, the results may contribute towards a differential diagnosis for fibromyalgia. |
| first_indexed | 2024-12-20T21:49:42Z |
| format | Article |
| id | doaj.art-4a03a330de3d43dd8063c53663121489 |
| institution | Directory Open Access Journal |
| issn | 1678-2690 |
| language | English |
| last_indexed | 2024-12-20T21:49:42Z |
| publishDate | 2014-12-01 |
| publisher | Academia Brasileira de Ciências |
| record_format | Article |
| series | Anais da Academia Brasileira de Ciências |
| spelling | doaj.art-4a03a330de3d43dd8063c536631214892022-12-21T19:25:35ZengAcademia Brasileira de CiênciasAnais da Academia Brasileira de Ciências1678-26902014-12-018641915191710.1590/0001-3765201420130081S0001-37652014000401915Soluble fractalkine in the plasma of fibromyalgia patientsJUAN J. GARCIAEDUARDO ORTEGAFibromyalgia is a form of non-articular rheumatism in which inflammatory cytokines seem to be involved. However, there is still no analytical specific diagnostic criterion for this disease. The aim was to examine a possible role of fractalkine as a biomarker in fibromyalgia. Plasma levels of soluble fractalkine were compared between women diagnosed with fibromyalgia (n=17) and healthy women (n=10) as controls. Fractalkine released by monocytes was also evaluated. Fibromyalgia patients showed lower plasma fractalkine than healthy women. Since most inflammatory pathologies show elevated plasma levels of soluble fractalkine, the results may contribute towards a differential diagnosis for fibromyalgia.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652014000401915&lng=en&tlng=enfractalcinafibromialgiabiomarcadorquimiocinamonócito |
| spellingShingle | JUAN J. GARCIA EDUARDO ORTEGA Soluble fractalkine in the plasma of fibromyalgia patients Anais da Academia Brasileira de Ciências fractalcina fibromialgia biomarcador quimiocina monócito |
| title | Soluble fractalkine in the plasma of fibromyalgia patients |
| title_full | Soluble fractalkine in the plasma of fibromyalgia patients |
| title_fullStr | Soluble fractalkine in the plasma of fibromyalgia patients |
| title_full_unstemmed | Soluble fractalkine in the plasma of fibromyalgia patients |
| title_short | Soluble fractalkine in the plasma of fibromyalgia patients |
| title_sort | soluble fractalkine in the plasma of fibromyalgia patients |
| topic | fractalcina fibromialgia biomarcador quimiocina monócito |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652014000401915&lng=en&tlng=en |
| work_keys_str_mv | AT juanjgarcia solublefractalkineintheplasmaoffibromyalgiapatients AT eduardoortega solublefractalkineintheplasmaoffibromyalgiapatients |