Genital Chlamydia trachomatis infections
Chlamydia trachomatis (C.t.) infection is one of the most prevalent sexually transmitted disease in Europe and in developed countries. The main biological features and pathogenic mechanisms of C.t. infection are summarized in this review. It usually occurs without symptoms and often goes undiagnosed...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2008-03-01
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| Series: | Microbiologia Medica |
| Subjects: | |
| Online Access: | http://www.pagepressjournals.org/index.php/mm/article/view/2591 |
| _version_ | 1818666153042509824 |
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| author | Maria Agnese Latino Daniela De Maria Andrea Caneparo Claudia Rosso Gianfranco De Intinis Anna Maria Calì Pierangelo Clerici Marco Cusini Ivano Dal Conte Tiziano Maggino Enrico Magliano Alfonso Panuccio Roberto Pozzoli Mario Rassu Barbara Suligoi Riccardo Terramocci |
| author_facet | Maria Agnese Latino Daniela De Maria Andrea Caneparo Claudia Rosso Gianfranco De Intinis Anna Maria Calì Pierangelo Clerici Marco Cusini Ivano Dal Conte Tiziano Maggino Enrico Magliano Alfonso Panuccio Roberto Pozzoli Mario Rassu Barbara Suligoi Riccardo Terramocci |
| author_sort | Maria Agnese Latino |
| collection | DOAJ |
| description | Chlamydia trachomatis (C.t.) infection is one of the most prevalent sexually transmitted disease in Europe and in developed countries. The main biological features and pathogenic mechanisms of C.t. infection are summarized in this review. It usually occurs without symptoms and often goes undiagnosed. If untreated, it can cause severe consequences for women, including pelvic inflammatory disease (PID), ectopic pregnancy and tubal infertility. Several studies have found that Chlamydia is more common among young women <25 years old, with multiple sexual partners within six months and non protected intercourses. Because re-infection rates are high, complications may be reduced if partners are treated and women re-tested. This paper emphasizes the importance of counselling and prevention programs and underlines that selective screening of high-risk population remains an essential component of C.t. control. In the last years, the detection of C.t. infection has been improved in sensitivity and specificity.We describe the main diagnostic techniques, from culture, enzyme immunoassay (EIA), direct fluorescent-antibody assay (DFA) to the new DNA-based test systems. Actually, NAATs (nucleic acid amplification tests) are regarded as the gold standard diagnostic techniques for chlamydial infections. |
| first_indexed | 2024-12-17T06:00:00Z |
| format | Article |
| id | doaj.art-4a05e885e62e4b2fae7736118e35cdad |
| institution | Directory Open Access Journal |
| issn | 2280-6423 |
| language | English |
| last_indexed | 2024-12-17T06:00:00Z |
| publishDate | 2008-03-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Microbiologia Medica |
| spelling | doaj.art-4a05e885e62e4b2fae7736118e35cdad2022-12-21T22:00:55ZengPAGEPress PublicationsMicrobiologia Medica2280-64232008-03-0123110.4081/mm.2008.25911844Genital Chlamydia trachomatis infectionsMaria Agnese LatinoDaniela De MariaAndrea CaneparoClaudia RossoGianfranco De IntinisAnna Maria CalìPierangelo ClericiMarco CusiniIvano Dal ConteTiziano MagginoEnrico MaglianoAlfonso PanuccioRoberto PozzoliMario RassuBarbara SuligoiRiccardo TerramocciChlamydia trachomatis (C.t.) infection is one of the most prevalent sexually transmitted disease in Europe and in developed countries. The main biological features and pathogenic mechanisms of C.t. infection are summarized in this review. It usually occurs without symptoms and often goes undiagnosed. If untreated, it can cause severe consequences for women, including pelvic inflammatory disease (PID), ectopic pregnancy and tubal infertility. Several studies have found that Chlamydia is more common among young women <25 years old, with multiple sexual partners within six months and non protected intercourses. Because re-infection rates are high, complications may be reduced if partners are treated and women re-tested. This paper emphasizes the importance of counselling and prevention programs and underlines that selective screening of high-risk population remains an essential component of C.t. control. In the last years, the detection of C.t. infection has been improved in sensitivity and specificity.We describe the main diagnostic techniques, from culture, enzyme immunoassay (EIA), direct fluorescent-antibody assay (DFA) to the new DNA-based test systems. Actually, NAATs (nucleic acid amplification tests) are regarded as the gold standard diagnostic techniques for chlamydial infections.http://www.pagepressjournals.org/index.php/mm/article/view/2591Chlamydia trachomatis, epidemiology, risk factors, diagnosis |
| spellingShingle | Maria Agnese Latino Daniela De Maria Andrea Caneparo Claudia Rosso Gianfranco De Intinis Anna Maria Calì Pierangelo Clerici Marco Cusini Ivano Dal Conte Tiziano Maggino Enrico Magliano Alfonso Panuccio Roberto Pozzoli Mario Rassu Barbara Suligoi Riccardo Terramocci Genital Chlamydia trachomatis infections Microbiologia Medica Chlamydia trachomatis, epidemiology, risk factors, diagnosis |
| title | Genital Chlamydia trachomatis infections |
| title_full | Genital Chlamydia trachomatis infections |
| title_fullStr | Genital Chlamydia trachomatis infections |
| title_full_unstemmed | Genital Chlamydia trachomatis infections |
| title_short | Genital Chlamydia trachomatis infections |
| title_sort | genital chlamydia trachomatis infections |
| topic | Chlamydia trachomatis, epidemiology, risk factors, diagnosis |
| url | http://www.pagepressjournals.org/index.php/mm/article/view/2591 |
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