Role of Vitamin D in Childhood Epilepsy
Background:Vitamin D is a fat-soluble vitamin and also considered a steroid hormone, that plays an important role in the proper functioning of many organs of the body.Adequate vitamin D status plays a very important role in terms of appropriate brain development and function .Regarding vitamin D,...
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Format: | Article |
Language: | English |
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South Valley University, Faculty of Medicine
2022-07-01
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Series: | SVU - International Journal of Medical Sciences |
Subjects: | |
Online Access: | https://svuijm.journals.ekb.eg/article_154646.html |
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author | Ahmed El-Abd Ahmed Mohammed H. Hassan Asmaa G. Mostafa * Ali Helmi Bakry |
author_facet | Ahmed El-Abd Ahmed Mohammed H. Hassan Asmaa G. Mostafa * Ali Helmi Bakry |
author_sort | Ahmed El-Abd Ahmed |
collection | DOAJ |
description | Background:Vitamin D is a fat-soluble vitamin and also considered a steroid hormone, that plays an important role in the proper functioning of many organs of the body.Adequate vitamin D status plays a very important role in terms of appropriate brain development and function .Regarding vitamin D,it's participation in the central nervous system's function is corroborated by the presence of the enzyme 25(OH)D3-1alpha-hydroxylase, which form of the active form of vitaminD, and the presence of receptors of vitamin D (VDR) in the brain tissue , mostly in the hypothalamus and substantia nigra. The aim of this review: is to evaluate the roleof vitamin D in childhood epilepsy and to study the vitamin D –antiepleptic drugs interactions among epileptic children.
Conclusion: vitamin D insufficiency and deficiency are highly prevalent among children with epilepsy.A lot of antiepileptic drugs lower vitamin D level and lead to more seizures specially enzyme inducers' drugs. |
first_indexed | 2024-04-13T05:20:06Z |
format | Article |
id | doaj.art-4a06df072f514c54bfe966b1ab543710 |
institution | Directory Open Access Journal |
issn | 2735-427X 2636-3402 |
language | English |
last_indexed | 2024-04-13T05:20:06Z |
publishDate | 2022-07-01 |
publisher | South Valley University, Faculty of Medicine |
record_format | Article |
series | SVU - International Journal of Medical Sciences |
spelling | doaj.art-4a06df072f514c54bfe966b1ab5437102022-12-22T03:00:46ZengSouth Valley University, Faculty of MedicineSVU - International Journal of Medical Sciences2735-427X2636-34022022-07-0152 410419https://dx.doi.org/10.21608/svuijm.2021.65108.1103 Role of Vitamin D in Childhood EpilepsyAhmed El-Abd Ahmed0Mohammed H. Hassan1https://orcid.org/0000-0003-2698-9438Asmaa G. Mostafa *2 Ali Helmi Bakry3Department of Pediatrics, Faculty of Medicine, South Valley University, Qena, Egypt.Department of Medical Biochemistry and Molecular Biology,Faculty of Medicine, South Valley University, Qena, EgyptDepartment of Pediatrics, Faculty of Medicine, South Valley University, Qena, Egypt.Department of Pediatrics, Faculty of Medicine, South Valley University, Qena, Egypt.Background:Vitamin D is a fat-soluble vitamin and also considered a steroid hormone, that plays an important role in the proper functioning of many organs of the body.Adequate vitamin D status plays a very important role in terms of appropriate brain development and function .Regarding vitamin D,it's participation in the central nervous system's function is corroborated by the presence of the enzyme 25(OH)D3-1alpha-hydroxylase, which form of the active form of vitaminD, and the presence of receptors of vitamin D (VDR) in the brain tissue , mostly in the hypothalamus and substantia nigra. The aim of this review: is to evaluate the roleof vitamin D in childhood epilepsy and to study the vitamin D –antiepleptic drugs interactions among epileptic children. Conclusion: vitamin D insufficiency and deficiency are highly prevalent among children with epilepsy.A lot of antiepileptic drugs lower vitamin D level and lead to more seizures specially enzyme inducers' drugs.https://svuijm.journals.ekb.eg/article_154646.htmlvitamin d; epilepsy; antiepileptic drugs |
spellingShingle | Ahmed El-Abd Ahmed Mohammed H. Hassan Asmaa G. Mostafa * Ali Helmi Bakry Role of Vitamin D in Childhood Epilepsy SVU - International Journal of Medical Sciences vitamin d; epilepsy; antiepileptic drugs |
title | Role of Vitamin D in Childhood Epilepsy |
title_full | Role of Vitamin D in Childhood Epilepsy |
title_fullStr | Role of Vitamin D in Childhood Epilepsy |
title_full_unstemmed | Role of Vitamin D in Childhood Epilepsy |
title_short | Role of Vitamin D in Childhood Epilepsy |
title_sort | role of vitamin d in childhood epilepsy |
topic | vitamin d; epilepsy; antiepileptic drugs |
url | https://svuijm.journals.ekb.eg/article_154646.html |
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