Multiple uses of dexmedetomidine in small animals: a mini review
Dexmedetomidine is an alpha-2 adrenergic agonist, which use had an exponential increase in human and veterinary medicine in the last 10 years. The aim of this mini review is to summarize the various uses of dexmedetomidine underlining its new applications and capabilities in the small animals’ clini...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-06-01
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| Series: | Frontiers in Veterinary Science |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fvets.2023.1135124/full |
| _version_ | 1797810772722581504 |
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| author | Chiara Di Franco Flavia Evangelista Flavia Evangelista Angela Briganti |
| author_facet | Chiara Di Franco Flavia Evangelista Flavia Evangelista Angela Briganti |
| author_sort | Chiara Di Franco |
| collection | DOAJ |
| description | Dexmedetomidine is an alpha-2 adrenergic agonist, which use had an exponential increase in human and veterinary medicine in the last 10 years. The aim of this mini review is to summarize the various uses of dexmedetomidine underlining its new applications and capabilities in the small animals’ clinical activity. While this drug was born as sedative in veterinary medicine, some studies demonstrated to be effective as an analgesic both in single administration and in continuous infusion. Recent studies have also shown the role of dexmedetomidine as an adjuvant during locoregional anesthesia, increasing the duration of the sensitive block and consequently decreasing the demand for systemic analgesics. The various analgesic properties make dexmedetomidine an interesting drug for opioid-free analgesia. Some studies highlighted a potential neuroprotective, cardioprotective and vasculoprotective role of dexmedetomidine, thus conferring it a place in critical care medicine, such as trauma and septic patients. Dexmedetomidine has demonstrated to be a multitasking molecule and it is ready to face new challenges. |
| first_indexed | 2024-03-13T07:12:48Z |
| format | Article |
| id | doaj.art-4a0ca5c22ad741b5ab94ee9c3244256f |
| institution | Directory Open Access Journal |
| issn | 2297-1769 |
| language | English |
| last_indexed | 2024-03-13T07:12:48Z |
| publishDate | 2023-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Veterinary Science |
| spelling | doaj.art-4a0ca5c22ad741b5ab94ee9c3244256f2023-06-05T15:30:58ZengFrontiers Media S.A.Frontiers in Veterinary Science2297-17692023-06-011010.3389/fvets.2023.11351241135124Multiple uses of dexmedetomidine in small animals: a mini reviewChiara Di Franco0Flavia Evangelista1Flavia Evangelista2Angela Briganti3Department of Veterinary Sciences, University of Pisa, Pisa, ItalyDepartment of Veterinary Sciences, University of Pisa, Pisa, ItalyVet Hospital H24, Firenze, ItalyDepartment of Veterinary Sciences, University of Pisa, Pisa, ItalyDexmedetomidine is an alpha-2 adrenergic agonist, which use had an exponential increase in human and veterinary medicine in the last 10 years. The aim of this mini review is to summarize the various uses of dexmedetomidine underlining its new applications and capabilities in the small animals’ clinical activity. While this drug was born as sedative in veterinary medicine, some studies demonstrated to be effective as an analgesic both in single administration and in continuous infusion. Recent studies have also shown the role of dexmedetomidine as an adjuvant during locoregional anesthesia, increasing the duration of the sensitive block and consequently decreasing the demand for systemic analgesics. The various analgesic properties make dexmedetomidine an interesting drug for opioid-free analgesia. Some studies highlighted a potential neuroprotective, cardioprotective and vasculoprotective role of dexmedetomidine, thus conferring it a place in critical care medicine, such as trauma and septic patients. Dexmedetomidine has demonstrated to be a multitasking molecule and it is ready to face new challenges.https://www.frontiersin.org/articles/10.3389/fvets.2023.1135124/fulldexmedetomidineveterinarysedationanalgesiahemodynamics |
| spellingShingle | Chiara Di Franco Flavia Evangelista Flavia Evangelista Angela Briganti Multiple uses of dexmedetomidine in small animals: a mini review Frontiers in Veterinary Science dexmedetomidine veterinary sedation analgesia hemodynamics |
| title | Multiple uses of dexmedetomidine in small animals: a mini review |
| title_full | Multiple uses of dexmedetomidine in small animals: a mini review |
| title_fullStr | Multiple uses of dexmedetomidine in small animals: a mini review |
| title_full_unstemmed | Multiple uses of dexmedetomidine in small animals: a mini review |
| title_short | Multiple uses of dexmedetomidine in small animals: a mini review |
| title_sort | multiple uses of dexmedetomidine in small animals a mini review |
| topic | dexmedetomidine veterinary sedation analgesia hemodynamics |
| url | https://www.frontiersin.org/articles/10.3389/fvets.2023.1135124/full |
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