Pregnancy in women with history of ischemic stroke and thrombophilia

Currently due to reduction of direct causes of maternal mortality increasing interest of scientists cause arterial thrombotic complications. Pregnancy-related stroke is a rare event, however, when it occurs, may be life threatening and there may be implications for management of the patient and deli...

Full description

Bibliographic Details
Main Authors: A. D. Makatsariya, S. V. Akinshina, V. O. Bitsadze, E. V. Zhuravleva, L. E. Idrisova, G. R. Abramyan
Format: Article
Language:Russian
Published: IRBIS LLC 2016-06-01
Series:Акушерство, гинекология и репродукция
Subjects:
Online Access:https://www.gynecology.su/jour/article/view/161
_version_ 1826567207912472576
author A. D. Makatsariya
S. V. Akinshina
V. O. Bitsadze
E. V. Zhuravleva
L. E. Idrisova
G. R. Abramyan
author_facet A. D. Makatsariya
S. V. Akinshina
V. O. Bitsadze
E. V. Zhuravleva
L. E. Idrisova
G. R. Abramyan
author_sort A. D. Makatsariya
collection DOAJ
description Currently due to reduction of direct causes of maternal mortality increasing interest of scientists cause arterial thrombotic complications. Pregnancy-related stroke is a rare event, however, when it occurs, may be life threatening and there may be implications for management of the patient and delivery. The mechanisms and risk factors for ischemic stroke related to pregnancy and in women of childbearing age remain unclear. Pathogenesis of so severe complication in young women is not fully understood, however, there is a concept thrombosis or cerebral embolism, which can develop on the background of well-known population-based risk factors such as hypertension, metabolic syndrome, smoking, heart rhythm disorders, valvular heart disease or in relation to typical obstetric pathologies, such as preeclampsia, massive obstetrical bleeding, septic complications, amniotic fluid embolism. In recent years, there is increasing interest in the role of thrombophilia in the pathogenesis of ischemic stroke, however, data on this issue is even more limited and contradictory than for venous thrombosis. Methods of prevention of recurrent stroke and strategies of pregnancy and delivery management in women with history of ischemic stroke are also contradictory.
first_indexed 2024-04-10T04:02:30Z
format Article
id doaj.art-4a115ec7c26f402ab75473a1f1946c95
institution Directory Open Access Journal
issn 2313-7347
2500-3194
language Russian
last_indexed 2025-03-14T11:03:53Z
publishDate 2016-06-01
publisher IRBIS LLC
record_format Article
series Акушерство, гинекология и репродукция
spelling doaj.art-4a115ec7c26f402ab75473a1f1946c952025-03-02T10:43:00ZrusIRBIS LLCАкушерство, гинекология и репродукция2313-73472500-31942016-06-0192899810.17749/2070-4968.2015.9.2.089-098159Pregnancy in women with history of ischemic stroke and thrombophiliaA. D. Makatsariya0S. V. Akinshina1V. O. Bitsadze2E. V. Zhuravleva3L. E. Idrisova4G. R. Abramyan5First Moscow State Medical Sechenov University of the Ministry of Health Russian FederationFirst Moscow State Medical Sechenov University of the Ministry of Health Russian FederationFirst Moscow State Medical Sechenov University of the Ministry of Health Russian FederationFirst Moscow State Medical Sechenov University of the Ministry of Health Russian FederationFirst Moscow State Medical Sechenov University of the Ministry of Health Russian FederationFirst Moscow State Medical Sechenov University of the Ministry of Health Russian FederationCurrently due to reduction of direct causes of maternal mortality increasing interest of scientists cause arterial thrombotic complications. Pregnancy-related stroke is a rare event, however, when it occurs, may be life threatening and there may be implications for management of the patient and delivery. The mechanisms and risk factors for ischemic stroke related to pregnancy and in women of childbearing age remain unclear. Pathogenesis of so severe complication in young women is not fully understood, however, there is a concept thrombosis or cerebral embolism, which can develop on the background of well-known population-based risk factors such as hypertension, metabolic syndrome, smoking, heart rhythm disorders, valvular heart disease or in relation to typical obstetric pathologies, such as preeclampsia, massive obstetrical bleeding, septic complications, amniotic fluid embolism. In recent years, there is increasing interest in the role of thrombophilia in the pathogenesis of ischemic stroke, however, data on this issue is even more limited and contradictory than for venous thrombosis. Methods of prevention of recurrent stroke and strategies of pregnancy and delivery management in women with history of ischemic stroke are also contradictory.https://www.gynecology.su/jour/article/view/161ischemic strokepregnancythrombophiliaantiphospholipid syndromelow molecular weight heparin
spellingShingle A. D. Makatsariya
S. V. Akinshina
V. O. Bitsadze
E. V. Zhuravleva
L. E. Idrisova
G. R. Abramyan
Pregnancy in women with history of ischemic stroke and thrombophilia
Акушерство, гинекология и репродукция
ischemic stroke
pregnancy
thrombophilia
antiphospholipid syndrome
low molecular weight heparin
title Pregnancy in women with history of ischemic stroke and thrombophilia
title_full Pregnancy in women with history of ischemic stroke and thrombophilia
title_fullStr Pregnancy in women with history of ischemic stroke and thrombophilia
title_full_unstemmed Pregnancy in women with history of ischemic stroke and thrombophilia
title_short Pregnancy in women with history of ischemic stroke and thrombophilia
title_sort pregnancy in women with history of ischemic stroke and thrombophilia
topic ischemic stroke
pregnancy
thrombophilia
antiphospholipid syndrome
low molecular weight heparin
url https://www.gynecology.su/jour/article/view/161
work_keys_str_mv AT admakatsariya pregnancyinwomenwithhistoryofischemicstrokeandthrombophilia
AT svakinshina pregnancyinwomenwithhistoryofischemicstrokeandthrombophilia
AT vobitsadze pregnancyinwomenwithhistoryofischemicstrokeandthrombophilia
AT evzhuravleva pregnancyinwomenwithhistoryofischemicstrokeandthrombophilia
AT leidrisova pregnancyinwomenwithhistoryofischemicstrokeandthrombophilia
AT grabramyan pregnancyinwomenwithhistoryofischemicstrokeandthrombophilia