Correlation between global longitudinal strain and SYNTAX score in coronary artery disease evaluation
Abstract Background Speckle tracking echocardiography may allow the evaluation of myocardial systolic and diastolic dynamics across different physiologic and pathologic conditions beyond traditional echocardiographic techniques. The use of STE longitudinal strain in identification and risk stratific...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2020-05-01
|
| Series: | The Egyptian Heart Journal |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s43044-020-00064-2 |
| _version_ | 1819056973541277696 |
|---|---|
| author | Gomaa Abdelrazek Alaa Yassin Khaled Elkhashab |
| author_facet | Gomaa Abdelrazek Alaa Yassin Khaled Elkhashab |
| author_sort | Gomaa Abdelrazek |
| collection | DOAJ |
| description | Abstract Background Speckle tracking echocardiography may allow the evaluation of myocardial systolic and diastolic dynamics across different physiologic and pathologic conditions beyond traditional echocardiographic techniques. The use of STE longitudinal strain in identification and risk stratification of CAD has good reproducibility and accuracy. The study aims to detect the relationship between SYNTAX score and global longitudinal peak systolic strain (GLPSS) in patients undergoing coronary angiography, with no history of myocardial infarction. Results The study included 70 symptomatic patients suspected to have chronic coronary syndrome aging 20–80 years (excluding those with significant structural heart disease). All patients underwent clinical evaluation, surface ECG, laboratory assessment, transthoracic echocardiographic (TTE), color TDI tracings, two-dimensional speckle tracking, and conventional coronary angiography with SYNTAX score calculation. Patients were divided into 3 groups based on the results of the coronary angiogram: normal CAD on angiogram (n = 10, control group), low SS (n = 25, SS < 22), and high SS (n = 35, SS ≥ 22). The mean age was 55 ± 9.6 years; 54% were males; two third of patients were hypertensive; 52% were diabetic; high percentage of high syntax score were noticed among males, diabetic patients, and smokers; and also low mean of GLS was noticed among diabetic patients and smokers. There was a statistically significant positive correlation between syntax score and each of LVEDD and LVESD and, on the other hand, statistically significant negative correlation between syntax score and each of E/A, GLS, AP2LS, AP3LS, and AP4LS was noticed. Peak GLS cutoff value of 17.8 and 16.5 showed 84% and 93% sensitivity and 70% and 91% specificity to detect high and low syntax score, respectively. Conclusion 2D longitudinal strain analysis has incremental diagnostic value over visual assessment during echocardiography in predicting significant coronary artery disease; GLS may offer a potential sensitive tool to detect significant CAD. |
| first_indexed | 2024-12-21T13:31:55Z |
| format | Article |
| id | doaj.art-4a145f0970b343c8b4ca6a301940374f |
| institution | Directory Open Access Journal |
| issn | 2090-911X |
| language | English |
| last_indexed | 2024-12-21T13:31:55Z |
| publishDate | 2020-05-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Heart Journal |
| spelling | doaj.art-4a145f0970b343c8b4ca6a301940374f2022-12-21T19:02:17ZengSpringerOpenThe Egyptian Heart Journal2090-911X2020-05-017211710.1186/s43044-020-00064-2Correlation between global longitudinal strain and SYNTAX score in coronary artery disease evaluationGomaa Abdelrazek0Alaa Yassin1Khaled Elkhashab2Fayoum UniversityFayoum UniversityFayoum UniversityAbstract Background Speckle tracking echocardiography may allow the evaluation of myocardial systolic and diastolic dynamics across different physiologic and pathologic conditions beyond traditional echocardiographic techniques. The use of STE longitudinal strain in identification and risk stratification of CAD has good reproducibility and accuracy. The study aims to detect the relationship between SYNTAX score and global longitudinal peak systolic strain (GLPSS) in patients undergoing coronary angiography, with no history of myocardial infarction. Results The study included 70 symptomatic patients suspected to have chronic coronary syndrome aging 20–80 years (excluding those with significant structural heart disease). All patients underwent clinical evaluation, surface ECG, laboratory assessment, transthoracic echocardiographic (TTE), color TDI tracings, two-dimensional speckle tracking, and conventional coronary angiography with SYNTAX score calculation. Patients were divided into 3 groups based on the results of the coronary angiogram: normal CAD on angiogram (n = 10, control group), low SS (n = 25, SS < 22), and high SS (n = 35, SS ≥ 22). The mean age was 55 ± 9.6 years; 54% were males; two third of patients were hypertensive; 52% were diabetic; high percentage of high syntax score were noticed among males, diabetic patients, and smokers; and also low mean of GLS was noticed among diabetic patients and smokers. There was a statistically significant positive correlation between syntax score and each of LVEDD and LVESD and, on the other hand, statistically significant negative correlation between syntax score and each of E/A, GLS, AP2LS, AP3LS, and AP4LS was noticed. Peak GLS cutoff value of 17.8 and 16.5 showed 84% and 93% sensitivity and 70% and 91% specificity to detect high and low syntax score, respectively. Conclusion 2D longitudinal strain analysis has incremental diagnostic value over visual assessment during echocardiography in predicting significant coronary artery disease; GLS may offer a potential sensitive tool to detect significant CAD.http://link.springer.com/article/10.1186/s43044-020-00064-2Chronic coronary syndromeTwo-dimensional speckle trackingGlobal longitudinal strainSYNTAX score |
| spellingShingle | Gomaa Abdelrazek Alaa Yassin Khaled Elkhashab Correlation between global longitudinal strain and SYNTAX score in coronary artery disease evaluation The Egyptian Heart Journal Chronic coronary syndrome Two-dimensional speckle tracking Global longitudinal strain SYNTAX score |
| title | Correlation between global longitudinal strain and SYNTAX score in coronary artery disease evaluation |
| title_full | Correlation between global longitudinal strain and SYNTAX score in coronary artery disease evaluation |
| title_fullStr | Correlation between global longitudinal strain and SYNTAX score in coronary artery disease evaluation |
| title_full_unstemmed | Correlation between global longitudinal strain and SYNTAX score in coronary artery disease evaluation |
| title_short | Correlation between global longitudinal strain and SYNTAX score in coronary artery disease evaluation |
| title_sort | correlation between global longitudinal strain and syntax score in coronary artery disease evaluation |
| topic | Chronic coronary syndrome Two-dimensional speckle tracking Global longitudinal strain SYNTAX score |
| url | http://link.springer.com/article/10.1186/s43044-020-00064-2 |
| work_keys_str_mv | AT gomaaabdelrazek correlationbetweengloballongitudinalstrainandsyntaxscoreincoronaryarterydiseaseevaluation AT alaayassin correlationbetweengloballongitudinalstrainandsyntaxscoreincoronaryarterydiseaseevaluation AT khaledelkhashab correlationbetweengloballongitudinalstrainandsyntaxscoreincoronaryarterydiseaseevaluation |