On the Determination of Mechanical Properties of Aqueous Microgels—Towards High-Throughput Characterization
Aqueous microgels are distinct entities of soft matter with mechanical signatures that can be different from their macroscopic counterparts due to confinement effects in the preparation, inherently made to consist of more than one domain (Janus particles) or further processing by coating and change...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-05-01
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| Series: | Gels |
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| Online Access: | https://www.mdpi.com/2310-2861/7/2/64 |
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| author | Ingrid Haga Oevreeide Renata Szydlak Marcin Luty Husnain Ahmed Victorien Prot Bjørn Helge Skallerud Joanna Zemła Małgorzata Lekka Bjørn Torger Stokke |
| author_facet | Ingrid Haga Oevreeide Renata Szydlak Marcin Luty Husnain Ahmed Victorien Prot Bjørn Helge Skallerud Joanna Zemła Małgorzata Lekka Bjørn Torger Stokke |
| author_sort | Ingrid Haga Oevreeide |
| collection | DOAJ |
| description | Aqueous microgels are distinct entities of soft matter with mechanical signatures that can be different from their macroscopic counterparts due to confinement effects in the preparation, inherently made to consist of more than one domain (Janus particles) or further processing by coating and change in the extent of crosslinking of the core. Motivated by the importance of the mechanical properties of such microgels from a fundamental point, but also related to numerous applications, we provide a perspective on the experimental strategies currently available and emerging tools being explored. Albeit all techniques in principle exploit enforcing stress and observing strain, the realization differs from directly, as, e.g., by atomic force microscope, to less evident in a fluid field combined with imaging by a high-speed camera in high-throughput strategies. Moreover, the accompanying analysis strategies also reflect such differences, and the level of detail that would be preferred for a comprehensive understanding of the microgel mechanical properties are not always implemented. Overall, the perspective is that current technologies have the capacity to provide detailed, nanoscopic mechanical characterization of microgels over an extended size range, to the high-throughput approaches providing distributions over the mechanical signatures, a feature not readily accessible by atomic force microscopy and micropipette aspiration. |
| first_indexed | 2024-03-10T10:50:41Z |
| format | Article |
| id | doaj.art-4a1923f193ca4fc7afc1ec0f2b93f47f |
| institution | Directory Open Access Journal |
| issn | 2310-2861 |
| language | English |
| last_indexed | 2024-03-10T10:50:41Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Gels |
| spelling | doaj.art-4a1923f193ca4fc7afc1ec0f2b93f47f2023-11-21T22:13:06ZengMDPI AGGels2310-28612021-05-01726410.3390/gels7020064On the Determination of Mechanical Properties of Aqueous Microgels—Towards High-Throughput CharacterizationIngrid Haga Oevreeide0Renata Szydlak1Marcin Luty2Husnain Ahmed3Victorien Prot4Bjørn Helge Skallerud5Joanna Zemła6Małgorzata Lekka7Bjørn Torger Stokke8Biophysics and Medical Technology, Department of Physics, NTNU The Norwegian University of Science and Technology, NO-7491 Trondheim, NorwayInstitute of Nuclear Physics, Polish Academy of Sciences, PL-31342 Krakow, PolandInstitute of Nuclear Physics, Polish Academy of Sciences, PL-31342 Krakow, PolandBiophysics and Medical Technology, Department of Physics, NTNU The Norwegian University of Science and Technology, NO-7491 Trondheim, NorwayBiomechanics, Department of Structural Engineering, NTNU The Norwegian University of Science and Technology, NO-7491 Trondheim, NorwayBiomechanics, Department of Structural Engineering, NTNU The Norwegian University of Science and Technology, NO-7491 Trondheim, NorwayInstitute of Nuclear Physics, Polish Academy of Sciences, PL-31342 Krakow, PolandInstitute of Nuclear Physics, Polish Academy of Sciences, PL-31342 Krakow, PolandBiophysics and Medical Technology, Department of Physics, NTNU The Norwegian University of Science and Technology, NO-7491 Trondheim, NorwayAqueous microgels are distinct entities of soft matter with mechanical signatures that can be different from their macroscopic counterparts due to confinement effects in the preparation, inherently made to consist of more than one domain (Janus particles) or further processing by coating and change in the extent of crosslinking of the core. Motivated by the importance of the mechanical properties of such microgels from a fundamental point, but also related to numerous applications, we provide a perspective on the experimental strategies currently available and emerging tools being explored. Albeit all techniques in principle exploit enforcing stress and observing strain, the realization differs from directly, as, e.g., by atomic force microscope, to less evident in a fluid field combined with imaging by a high-speed camera in high-throughput strategies. Moreover, the accompanying analysis strategies also reflect such differences, and the level of detail that would be preferred for a comprehensive understanding of the microgel mechanical properties are not always implemented. Overall, the perspective is that current technologies have the capacity to provide detailed, nanoscopic mechanical characterization of microgels over an extended size range, to the high-throughput approaches providing distributions over the mechanical signatures, a feature not readily accessible by atomic force microscopy and micropipette aspiration.https://www.mdpi.com/2310-2861/7/2/64microgelAFMmicropipette aspirationhigh-throughputmechanics |
| spellingShingle | Ingrid Haga Oevreeide Renata Szydlak Marcin Luty Husnain Ahmed Victorien Prot Bjørn Helge Skallerud Joanna Zemła Małgorzata Lekka Bjørn Torger Stokke On the Determination of Mechanical Properties of Aqueous Microgels—Towards High-Throughput Characterization Gels microgel AFM micropipette aspiration high-throughput mechanics |
| title | On the Determination of Mechanical Properties of Aqueous Microgels—Towards High-Throughput Characterization |
| title_full | On the Determination of Mechanical Properties of Aqueous Microgels—Towards High-Throughput Characterization |
| title_fullStr | On the Determination of Mechanical Properties of Aqueous Microgels—Towards High-Throughput Characterization |
| title_full_unstemmed | On the Determination of Mechanical Properties of Aqueous Microgels—Towards High-Throughput Characterization |
| title_short | On the Determination of Mechanical Properties of Aqueous Microgels—Towards High-Throughput Characterization |
| title_sort | on the determination of mechanical properties of aqueous microgels towards high throughput characterization |
| topic | microgel AFM micropipette aspiration high-throughput mechanics |
| url | https://www.mdpi.com/2310-2861/7/2/64 |
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