Changing Trends and Experience with Esophageal Cancer Surgery in a Single University Hospital: Are The Results Similar or Not?
Objective: The main treatment modality for esophageal cancer remains to be surgery. Over the last decades, surgical strategies have evolved remarkably. When neoadjuvant chemoradiotherapy became standard, discussions about the role, type, and timing of surgery began. In this study, we share results w...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2017-03-01
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| Series: | Bagcilar Medical Bulletin |
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http://behmedicalbulletin.org/archives/archive-detail/article-preview/changing-trends-and-experience-with-esophageal-can/23448
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| author | Sebahattin Celik Erkan Dogan Harun Arslan Abdussamed Batur Remzi Kiziltan Osman Toktas Ozkan Yilmaz M. Cetin Kotan |
| author_facet | Sebahattin Celik Erkan Dogan Harun Arslan Abdussamed Batur Remzi Kiziltan Osman Toktas Ozkan Yilmaz M. Cetin Kotan |
| author_sort | Sebahattin Celik |
| collection | DOAJ |
| description | Objective: The main treatment modality for esophageal cancer remains to be surgery. Over the last decades, surgical strategies have evolved remarkably. When neoadjuvant chemoradiotherapy became standard, discussions about the role, type, and timing of surgery began. In this study, we share results we obtained after operating our patients using various surgical techniques.Material and Methods:Reliable data from 51 esophageal cancer patients were evaluated retrospectively. Of the 51 cases, 31 were operable. These operable cases were further classified according to surgical method and neoadjuvant therapy status. Median survival time in months, complications, hospital mortality, length of hospital stay, and pathology results (total lymph nodes harvested and pathologic tumor node metastasis stage [p_TNM]) were documented for the different surgical approaches.Results: Open surgical methods were performed in 21 cases, while in 10 cases the Minimally Invasive Surgery (MIS) method was used. The MIS group received neoadjuvant therapy more frequently than the open surgical methods group (p=0.013). Although more complications were observed in the MIS group, the difference to the open esophagectomy methods group was not significant. Patients in the MIS group also had longer hospital stays, but again the difference was not significant. Although a pathologic complete response was seen in 8 of the 11 (72.7%) patients in our study who received chemoradiotherapy as neoadjuvant treatment, the surgical results of patients who received chemoradiotherapy were worse, although not to a statistically significant extent.Conclusion: Despite changing trends and treatment options in esophageal cancer surgery, we have yet to see the expected improved results. |
| first_indexed | 2024-04-10T12:00:15Z |
| format | Article |
| id | doaj.art-4a1a87fcb9e04ace9408564cf10439c6 |
| institution | Directory Open Access Journal |
| issn | 2547-9431 |
| language | English |
| last_indexed | 2024-04-10T12:00:15Z |
| publishDate | 2017-03-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Bagcilar Medical Bulletin |
| spelling | doaj.art-4a1a87fcb9e04ace9408564cf10439c62023-02-15T16:16:40ZengGalenos YayineviBagcilar Medical Bulletin2547-94312017-03-01211810.5350/BMB2017030309101413049054Changing Trends and Experience with Esophageal Cancer Surgery in a Single University Hospital: Are The Results Similar or Not?Sebahattin Celik0Erkan Dogan1Harun Arslan2Abdussamed Batur3Remzi Kiziltan4Osman Toktas5Ozkan Yilmaz6M. Cetin Kotan7 Yuzuncu Yil University, Faculty of Medicine, Department of General Surgery, Van-Turkey Yuzuncu Yil University, Faculty of Medicine, Department of Medical Oncology, Van-Turkey Yuzuncu Yil University, Faculty of Medicine, Department of Radiology, Van-Turkey Yuzuncu Yil University, Faculty of Medicine, Department of Radiology, Van-Turkey Yuzuncu Yil University, Faculty of Medicine, Department of General Surgery, Van-Turkey Yuzuncu Yil University, Faculty of Medicine, Department of General Surgery, Van-Turkey Yuzuncu Yil University, Faculty of Medicine, Department of General Surgery, Van-Turkey Yuzuncu Yil University, Faculty of Medicine, Department of General Surgery, Van-Turkey Objective: The main treatment modality for esophageal cancer remains to be surgery. Over the last decades, surgical strategies have evolved remarkably. When neoadjuvant chemoradiotherapy became standard, discussions about the role, type, and timing of surgery began. In this study, we share results we obtained after operating our patients using various surgical techniques.Material and Methods:Reliable data from 51 esophageal cancer patients were evaluated retrospectively. Of the 51 cases, 31 were operable. These operable cases were further classified according to surgical method and neoadjuvant therapy status. Median survival time in months, complications, hospital mortality, length of hospital stay, and pathology results (total lymph nodes harvested and pathologic tumor node metastasis stage [p_TNM]) were documented for the different surgical approaches.Results: Open surgical methods were performed in 21 cases, while in 10 cases the Minimally Invasive Surgery (MIS) method was used. The MIS group received neoadjuvant therapy more frequently than the open surgical methods group (p=0.013). Although more complications were observed in the MIS group, the difference to the open esophagectomy methods group was not significant. Patients in the MIS group also had longer hospital stays, but again the difference was not significant. Although a pathologic complete response was seen in 8 of the 11 (72.7%) patients in our study who received chemoradiotherapy as neoadjuvant treatment, the surgical results of patients who received chemoradiotherapy were worse, although not to a statistically significant extent.Conclusion: Despite changing trends and treatment options in esophageal cancer surgery, we have yet to see the expected improved results. http://behmedicalbulletin.org/archives/archive-detail/article-preview/changing-trends-and-experience-with-esophageal-can/23448 esophagus cancerminimally invasive surgeryneoadjuvant therapy |
| spellingShingle | Sebahattin Celik Erkan Dogan Harun Arslan Abdussamed Batur Remzi Kiziltan Osman Toktas Ozkan Yilmaz M. Cetin Kotan Changing Trends and Experience with Esophageal Cancer Surgery in a Single University Hospital: Are The Results Similar or Not? Bagcilar Medical Bulletin esophagus cancer minimally invasive surgery neoadjuvant therapy |
| title | Changing Trends and Experience with Esophageal Cancer Surgery in a Single University Hospital: Are The Results Similar or Not? |
| title_full | Changing Trends and Experience with Esophageal Cancer Surgery in a Single University Hospital: Are The Results Similar or Not? |
| title_fullStr | Changing Trends and Experience with Esophageal Cancer Surgery in a Single University Hospital: Are The Results Similar or Not? |
| title_full_unstemmed | Changing Trends and Experience with Esophageal Cancer Surgery in a Single University Hospital: Are The Results Similar or Not? |
| title_short | Changing Trends and Experience with Esophageal Cancer Surgery in a Single University Hospital: Are The Results Similar or Not? |
| title_sort | changing trends and experience with esophageal cancer surgery in a single university hospital are the results similar or not |
| topic | esophagus cancer minimally invasive surgery neoadjuvant therapy |
| url |
http://behmedicalbulletin.org/archives/archive-detail/article-preview/changing-trends-and-experience-with-esophageal-can/23448
|
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