HLA-Class II Artificial Antigen Presenting Cells in CD4+ T Cell-Based Immunotherapy

HLA-Class II Artificial Antigen Presenting Cells in CD4+ T Cell-Based Immunotherapy

CD4+ T cells differentiate into various T helper subsets characterized by distinct cytokine secreting profiles that confer them effector functions adapted to a variety of infectious or endogenous threats. Regulatory CD4+ T cells are another specialized subset that plays a fundamental role in the mai...

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Bibliographic Details
Main Authors: Alexandre Couture, Anthony Garnier, Fabian Docagne, Olivier Boyer, Denis Vivien, Brigitte Le-Mauff, Jean-Baptiste Latouche, Olivier Toutirais
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Immunology
Subjects:
CD4+ T lymphocytes
adoptive cell therapy
cancer
autoimmunity
artificial antigen presenting cells
HLA class II molecules
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01081/full

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