Proteomic studies of VEGFR2 in human placentas reveal protein associations with preeclampsia, diabetes, gravidity, and labor

Proteomic studies of VEGFR2 in human placentas reveal protein associations with preeclampsia, diabetes, gravidity, and labor

Abstract VEGFR2 (Vascular endothelial growth factor receptor 2) is a central regulator of placental angiogenesis. The study of the VEGFR2 proteome of chorionic villi at term revealed its partners MDMX (Double minute 4 protein) and PICALM (Phosphatidylinositol-binding clathrin assembly protein). Subs...

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Bibliographic Details
Main Authors: Shannon J. Ho, Dale Chaput, Rachel G. Sinkey, Amanda H. Garces, Erika P. New, Maja Okuka, Peng Sang, Sefa Arlier, Nihan Semerci, Thora S. Steffensen, Thomas J. Rutherford, Angel E. Alsina, Jianfeng Cai, Matthew L. Anderson, Ronald R. Magness, Vladimir N. Uversky, Derek A. T. Cummings, John C. M. Tsibris
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Cell Communication and Signaling
Subjects:
VEGFR2
MDMX
PICALM
Oxytocin receptor
Vasopressin receptor V1aR
Hofbauer cells
Online Access:https://doi.org/10.1186/s12964-024-01567-0

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