MicroRNAs and Metastasis
Metastasis, the development of secondary malignant growths at a distance from the primary site of a cancer, is associated with almost 90% of all cancer deaths, and half of all cancer patients present with some form of metastasis at the time of diagnosis. Consequently, there is a clear clinical need...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-12-01
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| Series: | Cancers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6694/12/1/96 |
| _version_ | 1797712456246624256 |
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| author | Carla Solé Charles H. Lawrie |
| author_facet | Carla Solé Charles H. Lawrie |
| author_sort | Carla Solé |
| collection | DOAJ |
| description | Metastasis, the development of secondary malignant growths at a distance from the primary site of a cancer, is associated with almost 90% of all cancer deaths, and half of all cancer patients present with some form of metastasis at the time of diagnosis. Consequently, there is a clear clinical need for a better understanding of metastasis. The role of miRNAs in the metastatic process is beginning to be explored. However, much is still to be understood. In this review, we present the accumulating evidence for the importance of miRNAs in metastasis as key regulators of this hallmark of cancer. |
| first_indexed | 2024-03-12T07:22:08Z |
| format | Article |
| id | doaj.art-4a2115664bcd466498407e16809690b7 |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-12T07:22:08Z |
| publishDate | 2019-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-4a2115664bcd466498407e16809690b72023-09-02T22:21:43ZengMDPI AGCancers2072-66942019-12-011219610.3390/cancers12010096cancers12010096MicroRNAs and MetastasisCarla Solé0Charles H. Lawrie1Molecular Oncology Group, Biodonostia Research Institute, 20014 San Sebastián, SpainMolecular Oncology Group, Biodonostia Research Institute, 20014 San Sebastián, SpainMetastasis, the development of secondary malignant growths at a distance from the primary site of a cancer, is associated with almost 90% of all cancer deaths, and half of all cancer patients present with some form of metastasis at the time of diagnosis. Consequently, there is a clear clinical need for a better understanding of metastasis. The role of miRNAs in the metastatic process is beginning to be explored. However, much is still to be understood. In this review, we present the accumulating evidence for the importance of miRNAs in metastasis as key regulators of this hallmark of cancer.https://www.mdpi.com/2072-6694/12/1/96mirnametastasiscancerliquid biopsies |
| spellingShingle | Carla Solé Charles H. Lawrie MicroRNAs and Metastasis Cancers mirna metastasis cancer liquid biopsies |
| title | MicroRNAs and Metastasis |
| title_full | MicroRNAs and Metastasis |
| title_fullStr | MicroRNAs and Metastasis |
| title_full_unstemmed | MicroRNAs and Metastasis |
| title_short | MicroRNAs and Metastasis |
| title_sort | micrornas and metastasis |
| topic | mirna metastasis cancer liquid biopsies |
| url | https://www.mdpi.com/2072-6694/12/1/96 |
| work_keys_str_mv | AT carlasole micrornasandmetastasis AT charleshlawrie micrornasandmetastasis |