Intravenous infusion of small umbilical cord mesenchymal stem cells could enhance safety and delay retinal degeneration in RCS rats

Intravenous infusion of small umbilical cord mesenchymal stem cells could enhance safety and delay retinal degeneration in RCS rats

Abstract Background Human umbilical cord mesenchymal stem cells (UCMSCs) transplantation is a promising therapy for the treatment of retinitis pigmentosa (RP). However, intravenously infused cells may be blocked in the lung, increasing the risk of vascular obstruction, which needs to be optimized to...

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Bibliographic Details
Main Authors: Qingling Liang, Qiyou Li, Bangqi Ren, Zheng Qin Yin
Format: Article
Language:English
Published: BMC 2022-02-01
Series:BMC Ophthalmology
Subjects:
Umbilical cord mesenchymal stem cells
Intravenous infusion
Safety
Efficacy
Retinitis pigmentosa
Online Access:https://doi.org/10.1186/s12886-021-02171-3

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