Voltage gated potassium channel antibodies positive autoimmune encephalopathy in a child: A case report and literature review of an under-recognized condition

Autoimmune limbic encephalitis (LE) associated with voltage gated potassium channel antibodies (VGKC-Abs) in children is more common than previously thought and is not always paraneoplastic. Non-neoplastic, autoimmune LE associated with VGKC-Abs has been described recently. However, only few case re...

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Main Authors: Subramanian Ganesan, Sushil Beri, Beri Khan, Nahin Hussain
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-01-01
Series:Annals of Indian Academy of Neurology
Subjects:
Online Access:http://www.annalsofian.org/article.asp?issn=0972-2327;year=2013;volume=16;issue=4;spage=593;epage=596;aulast=Ganesan
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author Subramanian Ganesan
Sushil Beri
Beri Khan
Nahin Hussain
author_facet Subramanian Ganesan
Sushil Beri
Beri Khan
Nahin Hussain
author_sort Subramanian Ganesan
collection DOAJ
description Autoimmune limbic encephalitis (LE) associated with voltage gated potassium channel antibodies (VGKC-Abs) in children is more common than previously thought and is not always paraneoplastic. Non-neoplastic, autoimmune LE associated with VGKC-Abs has been described recently. However, only few case reports in children as the disease is predominantly described in the adult population. It is likely that this type of autoimmune encephalitis is currently under-diagnosed and hence, under-treated, especially in children. We present a 13-year-old previously fit and healthy African girl diagnosed with LE and we reviewed the literature for its current management.
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spelling doaj.art-4a258532fbe24bbc853a9231d3d7ff5b2022-12-22T02:15:44ZengWolters Kluwer Medknow PublicationsAnnals of Indian Academy of Neurology0972-23271998-35492013-01-0116459359610.4103/0972-2327.120483Voltage gated potassium channel antibodies positive autoimmune encephalopathy in a child: A case report and literature review of an under-recognized conditionSubramanian GanesanSushil BeriBeri KhanNahin HussainAutoimmune limbic encephalitis (LE) associated with voltage gated potassium channel antibodies (VGKC-Abs) in children is more common than previously thought and is not always paraneoplastic. Non-neoplastic, autoimmune LE associated with VGKC-Abs has been described recently. However, only few case reports in children as the disease is predominantly described in the adult population. It is likely that this type of autoimmune encephalitis is currently under-diagnosed and hence, under-treated, especially in children. We present a 13-year-old previously fit and healthy African girl diagnosed with LE and we reviewed the literature for its current management.http://www.annalsofian.org/article.asp?issn=0972-2327;year=2013;volume=16;issue=4;spage=593;epage=596;aulast=GanesanLimbic encephalitisparaneoplasticvoltage gated potassium channel antibodies
spellingShingle Subramanian Ganesan
Sushil Beri
Beri Khan
Nahin Hussain
Voltage gated potassium channel antibodies positive autoimmune encephalopathy in a child: A case report and literature review of an under-recognized condition
Annals of Indian Academy of Neurology
Limbic encephalitis
paraneoplastic
voltage gated potassium channel antibodies
title Voltage gated potassium channel antibodies positive autoimmune encephalopathy in a child: A case report and literature review of an under-recognized condition
title_full Voltage gated potassium channel antibodies positive autoimmune encephalopathy in a child: A case report and literature review of an under-recognized condition
title_fullStr Voltage gated potassium channel antibodies positive autoimmune encephalopathy in a child: A case report and literature review of an under-recognized condition
title_full_unstemmed Voltage gated potassium channel antibodies positive autoimmune encephalopathy in a child: A case report and literature review of an under-recognized condition
title_short Voltage gated potassium channel antibodies positive autoimmune encephalopathy in a child: A case report and literature review of an under-recognized condition
title_sort voltage gated potassium channel antibodies positive autoimmune encephalopathy in a child a case report and literature review of an under recognized condition
topic Limbic encephalitis
paraneoplastic
voltage gated potassium channel antibodies
url http://www.annalsofian.org/article.asp?issn=0972-2327;year=2013;volume=16;issue=4;spage=593;epage=596;aulast=Ganesan
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AT sushilberi voltagegatedpotassiumchannelantibodiespositiveautoimmuneencephalopathyinachildacasereportandliteraturereviewofanunderrecognizedcondition
AT berikhan voltagegatedpotassiumchannelantibodiespositiveautoimmuneencephalopathyinachildacasereportandliteraturereviewofanunderrecognizedcondition
AT nahinhussain voltagegatedpotassiumchannelantibodiespositiveautoimmuneencephalopathyinachildacasereportandliteraturereviewofanunderrecognizedcondition