Comparison of Short-Term Clinical Outcome of Non-ST Elevation versus ST Elevation Myocardial Infarction

Background: Studies on the prognosis of ST elevation myocardial infarction (STEMI) versus non-ST elevation myocardial infarction (non-STEMI) have shown different results. The present study was designed to compare the early outcome and left ventricular systolic function of patients with ST and non-ST...

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Main Authors: Elham Hakki, Mahmood Sheikhfathollahi, Mehran Mahmoodian, Mehrdad Sheikhvatan, Hakimeh Sadeghian, Afsaneh Sadeghian, Behnaz Behnam, Ali Mohammad Haji Zeinali, Vahid Semnani
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2009-06-01
Series:Journal of Tehran University Heart Center
Subjects:
Online Access:http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/13511.pdf&manuscript_id=13511
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author Elham Hakki
Mahmood Sheikhfathollahi
Mehran Mahmoodian
Mehrdad Sheikhvatan
Hakimeh Sadeghian
Afsaneh Sadeghian
Behnaz Behnam
Ali Mohammad Haji Zeinali
Vahid Semnani
author_facet Elham Hakki
Mahmood Sheikhfathollahi
Mehran Mahmoodian
Mehrdad Sheikhvatan
Hakimeh Sadeghian
Afsaneh Sadeghian
Behnaz Behnam
Ali Mohammad Haji Zeinali
Vahid Semnani
author_sort Elham Hakki
collection DOAJ
description Background: Studies on the prognosis of ST elevation myocardial infarction (STEMI) versus non-ST elevation myocardial infarction (non-STEMI) have shown different results. The present study was designed to compare the early outcome and left ventricular systolic function of patients with ST and non-ST elevation myocardial infarction. Methods: The patients' information was derived from 10,065 consecutive patients hospitalized in Tehran Heart Center with acute MI (2007 patients with STEMI and 8058 with non-STEMI). The baseline clinical characteristics, post-MI complications, left ventricular systolic functions, and 30-day mortality rates were compared. Results: A history of current cigarette smoking, opium addiction, and brain stroke was more frequent in the STEMI patients, whereas hyperlipidemia, hypertension, and obesity were found more in the non-STEMI group. Ejection fraction was higher in the non-STEMI patients than that in the STEMI group, and anterior wall infarction was detected more frequently in the STEMI cases. A history of coronary artery bypass grafting and also percutaneous coronary intervention was observed more in the non-STEMI group. Amongst the in-hospital complications, ventricular arrhythmias (1.4 vs. 0.5, P<0.001) and pulmonary edema (0.4 vs. 0.1, P=0.002) were more prevalent in the STEMI cases. The 30-day mortality rate in the STEMI group was higher than that in the non-STEMI group (5.5 vs. 2.4, P<0.001). Early mortality in both groups was dependant on advanced age, diabetes mellitus, post-MI bradycardia, and atrioventricular block. Also, female gender and pulmonary edema in the STEMI group and family history of MI in the non-STEMI patients could predict 30-day mortality. Conclusion: There were several differences in the baseline characteristics and early outcome between the two types of STEMI and non-STEMI. The 30-day mortality rate was higher in the STEMI group than that in the non-STEMI group.
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spelling doaj.art-4a2b49a7369f4c5681dd161c32ee3a772022-12-22T00:49:13ZengTehran University of Medical SciencesJournal of Tehran University Heart Center1735-86202009-06-014297102Comparison of Short-Term Clinical Outcome of Non-ST Elevation versus ST Elevation Myocardial InfarctionElham HakkiMahmood SheikhfathollahiMehran MahmoodianMehrdad SheikhvatanHakimeh SadeghianAfsaneh SadeghianBehnaz BehnamAli Mohammad Haji ZeinaliVahid SemnaniBackground: Studies on the prognosis of ST elevation myocardial infarction (STEMI) versus non-ST elevation myocardial infarction (non-STEMI) have shown different results. The present study was designed to compare the early outcome and left ventricular systolic function of patients with ST and non-ST elevation myocardial infarction. Methods: The patients' information was derived from 10,065 consecutive patients hospitalized in Tehran Heart Center with acute MI (2007 patients with STEMI and 8058 with non-STEMI). The baseline clinical characteristics, post-MI complications, left ventricular systolic functions, and 30-day mortality rates were compared. Results: A history of current cigarette smoking, opium addiction, and brain stroke was more frequent in the STEMI patients, whereas hyperlipidemia, hypertension, and obesity were found more in the non-STEMI group. Ejection fraction was higher in the non-STEMI patients than that in the STEMI group, and anterior wall infarction was detected more frequently in the STEMI cases. A history of coronary artery bypass grafting and also percutaneous coronary intervention was observed more in the non-STEMI group. Amongst the in-hospital complications, ventricular arrhythmias (1.4 vs. 0.5, P<0.001) and pulmonary edema (0.4 vs. 0.1, P=0.002) were more prevalent in the STEMI cases. The 30-day mortality rate in the STEMI group was higher than that in the non-STEMI group (5.5 vs. 2.4, P<0.001). Early mortality in both groups was dependant on advanced age, diabetes mellitus, post-MI bradycardia, and atrioventricular block. Also, female gender and pulmonary edema in the STEMI group and family history of MI in the non-STEMI patients could predict 30-day mortality. Conclusion: There were several differences in the baseline characteristics and early outcome between the two types of STEMI and non-STEMI. The 30-day mortality rate was higher in the STEMI group than that in the non-STEMI group.http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/13511.pdf&manuscript_id=13511Myocardial infarctionOutcome assessmentMortality
spellingShingle Elham Hakki
Mahmood Sheikhfathollahi
Mehran Mahmoodian
Mehrdad Sheikhvatan
Hakimeh Sadeghian
Afsaneh Sadeghian
Behnaz Behnam
Ali Mohammad Haji Zeinali
Vahid Semnani
Comparison of Short-Term Clinical Outcome of Non-ST Elevation versus ST Elevation Myocardial Infarction
Journal of Tehran University Heart Center
Myocardial infarction
Outcome assessment
Mortality
title Comparison of Short-Term Clinical Outcome of Non-ST Elevation versus ST Elevation Myocardial Infarction
title_full Comparison of Short-Term Clinical Outcome of Non-ST Elevation versus ST Elevation Myocardial Infarction
title_fullStr Comparison of Short-Term Clinical Outcome of Non-ST Elevation versus ST Elevation Myocardial Infarction
title_full_unstemmed Comparison of Short-Term Clinical Outcome of Non-ST Elevation versus ST Elevation Myocardial Infarction
title_short Comparison of Short-Term Clinical Outcome of Non-ST Elevation versus ST Elevation Myocardial Infarction
title_sort comparison of short term clinical outcome of non st elevation versus st elevation myocardial infarction
topic Myocardial infarction
Outcome assessment
Mortality
url http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/13511.pdf&manuscript_id=13511
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