Effects of the Storage Conditions on the Stability of Natural and Synthetic Cannabis in Biological Matrices for Forensic Toxicology Analysis: An Update from the Literature

The use and abuse of cannabis, be it for medicinal or recreational purposes, is widely spread among the population. Consequently, a market for more potent and consequently more toxic synthetic cannabinoids has flourished, and with it, the need for accurate testing of these substances in intoxicated...

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Main Authors: Elias Djilali, Lucia Pappalardo, Anna Maria Posadino, Roberta Giordo, Gianfranco Pintus
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/12/9/801
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author Elias Djilali
Lucia Pappalardo
Anna Maria Posadino
Roberta Giordo
Gianfranco Pintus
author_facet Elias Djilali
Lucia Pappalardo
Anna Maria Posadino
Roberta Giordo
Gianfranco Pintus
author_sort Elias Djilali
collection DOAJ
description The use and abuse of cannabis, be it for medicinal or recreational purposes, is widely spread among the population. Consequently, a market for more potent and consequently more toxic synthetic cannabinoids has flourished, and with it, the need for accurate testing of these substances in intoxicated people. In this regard, one of the critical factors in forensic toxicology is the stability of these drugs in different biological matrices due to different storage conditions. This review aims to present the most updated and relevant literature of studies performed on the effects of different storage conditions on the stability of cannabis compounds present in various biological matrices, such as blood and plasma, urine, and oral fluids, as well as in alternative matrices, such as breath, bile fluid, hair, sweat, cerumen, and dried blood spots.
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spelling doaj.art-4a2b78843e404323b0b01551aafcd41f2023-11-23T17:43:54ZengMDPI AGMetabolites2218-19892022-08-0112980110.3390/metabo12090801Effects of the Storage Conditions on the Stability of Natural and Synthetic Cannabis in Biological Matrices for Forensic Toxicology Analysis: An Update from the LiteratureElias Djilali0Lucia Pappalardo1Anna Maria Posadino2Roberta Giordo3Gianfranco Pintus4Department of Biology, Chemistry and Environmental Sciences, American University of Sharjah, Sharjah P.O. Box 26666, United Arab EmiratesDepartment of Biology, Chemistry and Environmental Sciences, American University of Sharjah, Sharjah P.O. Box 26666, United Arab EmiratesDepartment of Biomedical Sciences, University of Sassari, 07100 Sassari, ItalyCollege of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai P.O. Box 505055, United Arab EmiratesDepartment of Biomedical Sciences, University of Sassari, 07100 Sassari, ItalyThe use and abuse of cannabis, be it for medicinal or recreational purposes, is widely spread among the population. Consequently, a market for more potent and consequently more toxic synthetic cannabinoids has flourished, and with it, the need for accurate testing of these substances in intoxicated people. In this regard, one of the critical factors in forensic toxicology is the stability of these drugs in different biological matrices due to different storage conditions. This review aims to present the most updated and relevant literature of studies performed on the effects of different storage conditions on the stability of cannabis compounds present in various biological matrices, such as blood and plasma, urine, and oral fluids, as well as in alternative matrices, such as breath, bile fluid, hair, sweat, cerumen, and dried blood spots.https://www.mdpi.com/2218-1989/12/9/801cannabinoidsstabilityurineplasmaoral fluidshair
spellingShingle Elias Djilali
Lucia Pappalardo
Anna Maria Posadino
Roberta Giordo
Gianfranco Pintus
Effects of the Storage Conditions on the Stability of Natural and Synthetic Cannabis in Biological Matrices for Forensic Toxicology Analysis: An Update from the Literature
Metabolites
cannabinoids
stability
urine
plasma
oral fluids
hair
title Effects of the Storage Conditions on the Stability of Natural and Synthetic Cannabis in Biological Matrices for Forensic Toxicology Analysis: An Update from the Literature
title_full Effects of the Storage Conditions on the Stability of Natural and Synthetic Cannabis in Biological Matrices for Forensic Toxicology Analysis: An Update from the Literature
title_fullStr Effects of the Storage Conditions on the Stability of Natural and Synthetic Cannabis in Biological Matrices for Forensic Toxicology Analysis: An Update from the Literature
title_full_unstemmed Effects of the Storage Conditions on the Stability of Natural and Synthetic Cannabis in Biological Matrices for Forensic Toxicology Analysis: An Update from the Literature
title_short Effects of the Storage Conditions on the Stability of Natural and Synthetic Cannabis in Biological Matrices for Forensic Toxicology Analysis: An Update from the Literature
title_sort effects of the storage conditions on the stability of natural and synthetic cannabis in biological matrices for forensic toxicology analysis an update from the literature
topic cannabinoids
stability
urine
plasma
oral fluids
hair
url https://www.mdpi.com/2218-1989/12/9/801
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