Hyperferritinemia, Low Circulating Iron and Elevated Hepcidin May Negatively Impact Outcome in COVID-19 Patients: A Pilot Study

Hyperferritinemia, Low Circulating Iron and Elevated Hepcidin May Negatively Impact Outcome in COVID-19 Patients: A Pilot Study

Inflammation in COVID-19 produces intracellular iron overload with low circulating iron available for metabolic processes. The accumulated intracellular iron generates reactive species of oxygen and results in ferroptosis, a non-programmed cell death. Since no organ is spared, iron dysmetabolism inc...

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Bibliographic Details
Main Authors: Robert Szabo, Cristina Petrisor, Constantin Bodolea, Robert Simon, Ioana Maries, Sebastian Tranca, Teodora Mocan
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Antioxidants
Subjects:
COVID-19
iron overload
inflammation
hepcidin
interleukin 6
ferritin
Online Access:https://www.mdpi.com/2076-3921/11/7/1364

Internet

https://www.mdpi.com/2076-3921/11/7/1364

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